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Eunae Choi,Jun-Im Song 한국동물분류학회 2015 Animal Systematics, Evolution and Diversity Vol.31 No.2
The two zooxanthellate scleractinian corals are newly recorded in Korea: Psammocora albopicta Benzoni, 2006 of the family Psammocoridae and Oulastrea crispata (Lamarck, 1816) of the family Faviidae. These families are also newly recorded in Korea. Specimens were collected from the subtidal zones of Jeju-do Island, Korea by SCUBA diving from 1999 to 2014. Two scleractinians are described based on the morphological characters of skeletal structures. Psammocora albopicta is distinguished by its encrusting cerioid growth form, high density of corallites, small calicular diameter, single styliform columella, and fewer rows of enclosed septa. Oulastrea crispata is characterized by its encrusting plocoid growth form, polygonal calicular shape, irregular paliform lobes, and papillose columella.
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Congenital fetal syphilis presenting with progression of ultrasound findings: A case report
( Eunae Jo ),( Hyung Eun Choi ),( Su Kyung Jung ),( Sina Jang ),( Jeong Ok Kim ),( Jeonghoon Lee ),( Ho Yeon Kim ),( Eun Seop Song ),( Byoung Ick Lee ),( Sung Ook Hwang ),( Soo Ran Choi ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
Congenital fetal syphilis can cause by spirochetes cross the placenta from about 14 weeks of gestation. The clinical manifestations of congenital fetal syphilis are the results of active infection and inflammation and they are influenced by gestational age, stage of maternal syphilis, maternal treatment, and immunological response of the fetus. Untreated syphilis in pregnancy leads to adverse outcomes, including still birth, prematurity, low birth weight, congenital disease among newborn babies. We have a case of active fetal syphilis infection and rapid course of disease in untreated maternal primary infection. A 16-year-old woman at 28+2 weeks of gestation was referred with maternal reactive of FTA-ABS Ig M and Ig G, and fetal hepatosplenomegaly, severe ascites, and thickened placenta on ultrasound scan. The woman had a history of painless small vulvar sore about one month ago, and a report of ultrasound scan showed fetal abdomen with scanty ascites at 27+3 weeks of gestation. Thus the woman had started treatment with benzathine penicillin 2.4 million units. However, the fetus resulted in intrauterine fetal death at 28+6 weeks gestation with severe fetal hydropse, ascites, and pleural effusion. Polymerase chain reaction of amniotic fluid for Treponema pallidum was positive and FTA-ABS Ig M in cord blood was reactive. It is important in all pregnant women during the first trimester of pregnancy should be screened serologically for syphilis.
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Choi, Eunae,Song, Jun-Im The Korean Society of Systematic Zoology 2017 Animal Systematics, Evolution and Diversity Vol.33 No.2
This study reports three species in the genus Tubastraea from Korea: Tubastraea coccinea Lesson, 1829; Tubastraea faulkneri Wells, 1982; and Tubastraea micranthus (Ehrenberg, 1834). Tubastraea faulkneri and T. micranthus are newly recorded in Korea. The specimens of three species were collected in the subtidal zones off Jeju-do between 1991 and 2010. The two newly recorded species were described in detail based upon the morphological characters of skeletal structures. The previous records of T. coccinea in Korea were supplemented with additional data in the remarks. These three species have a straight septal arrangement or irregular septal fusion in common as a main character for the genus Tubastraea, but they differ with respect to the growth form, intercorallite distance, exsertness from common coenosteum, and the detailed characters of septal arrangement. Tubastraea faulkneri is similar to T. coccinea in its plocoid growth form, well developed common coenosteum, and corallite size. However, unlike the latter species, the former species is characterized by rare or absent budding adjacent to the corallite edges, wider intercorallite distance, and irregularly developed septal fusion near the columella. In particular, T. micranthus is distinguished by an axial dendroid growth form, and the smallest corallites in this genus.
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Eunae Choi,Jun-Im Song 한국동물분류학회 2017 Animal Systematics, Evolution and Diversity Vol.33 No.2
This study reports three species in the genus Tubastraea from Korea: Tubastraea coccinea Lesson, 1829; Tubastraea faulkneri Wells, 1982; and Tubastraea micranthus (Ehrenberg, 1834). Tubastraea faulkneri and T. micranthus are newly recorded in Korea. The specimens of three species were collected in the subtidal zones off Jeju-do between 1991 and 2010. The two newly recorded species were described in detail based upon the morphological characters of skeletal structures. The previous records of T. coccinea in Korea were supplemented with additional data in the remarks. These three species have a straight septal arrangement or irregular septal fusion in common as a main character for the genus Tubastraea, but they differ with respect to the growth form, intercorallite distance, exsertness from common coenosteum, and the detailed characters of septal arrangement. Tubastraea faulkneri is similar to T. coccinea in its plocoid growth form, well developed common coenosteum, and corallite size. However, unlike the latter species, the former species is characterized by rare or absent budding adjacent to the corallite edges, wider intercorallite distance, and irregularly developed septal fusion near the columella. In particular, T. micranthus is distinguished by an axial dendroid growth form, and the smallest corallites in this genus.
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Choi, Eunae,Song, Jun-Im The Korean Society of Systematic Zoology 2016 Animal Systematics, Evolution and Diversity Vol.32 No.1
Dendrophyllia compressa Ogawa and Takahashi, 1995 is newly reported from Korea. The specimen was collected off Seogwipo, Jeju-do, Korea in 1969. It is described herein based on the morphological characters of the skeletal structures. Dendrophyllia compressa is characterized by its small and bushy growth form with branches, vertical growth direction, small calicular diameter, compressed calice, Pourtalès Plan with vertical septal inner edges, flat and spongy columella, exserted septal upper margins, and epitheca. Dendrophyllia compressa has been synonymized with Cladopsammia eguchii . However, the former species differs from the latter species in its growth form, growth direction, colony size, corallite size, and corallite shape.
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Choi, Jae Min,Lee, Benel,Jeong, Daham,Park, Kyeong Hui,Choi, Eun-Ji,Jeon, Yong-Joon,Dindulkar, Someshwar D.,Cho, Eunae,Do, Sun Hee,Lee, Kyungho,Lee, Im-Soon,Park, Seyeon,Jun, Bong-Hyun,Yu, Jae-Hyuk,Ju THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING 2017 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY -S Vol.48 No.-
<P><B>Abstract</B></P> <P>Hydroxypropyl cyclosophoraose-pullulan (HPCys-Pul) microspheres were designed as a novel hybrid system of biocompatible pullulan matrice and pendant hydroxypropyl cyclosophoraoses with drug complexing ability. The HPCys-Pul microspheres were prepared by emulsion crosslinking method, and characterized using thermogravimetric analysis, Fourier transform infrared spectroscopy, scanning electron microscopy, and solid state NMR spectroscopy. By virtue of hydroxypropyl cyclosophoraoses, the developed microspheres can encapsulate 4.2-fold more naproxen than pullulan microspheres. Korsmeyer–Peppas model was introduced for describing release kinetics. <I>In vivo</I> naproxen release analysis was carried out in Sprague-Dawley (SD) rats. From those results HPCys-Pul microsphere will be a promising platform for controlled drug delivery.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Hybrid microspheres of biocompatible polysaccharide pullulan (Pul) and hydroxypropyl cyclosophoraoses (HPCys) were prepared. </LI> <LI> The HPCys-Pul microspheres showed both effective encapsulation and controlled release of naproxen (NPX). </LI> <LI> Those microspheres were completely characterized by TGA, XRD, FE-SEM, FT-IR, and solid-state NMR spectroscopy. </LI> <LI> Hybrid HPCys-Pul microspheres resulted in a pH-regulated release system as well as enhanced entrapment efficiency for NPX. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Choi, Jae Min,Park, Kyeonghui,Lee, Benel,Jeong, Daham,Dindulkar, Someshwar D,Choi, Youngjin,Cho, Eunae,Park, Seyeon,Yu, Jae-hyuk,Jung, Seunho Elsevier 2017 Carbohydrate polymers Vol.163 No.-
<P><B>Abstract</B></P> <P>Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat bacterial infections; however, its limited aqueous solubility inhibits its broader clinical uses. This study investigated the complexation effect of mono-6-deoxy-6-aminoethylamino-β-cyclodextrin on the aqueous solubility and bioavailability of ciprofloxacin. During complexation, the oval-shaped cavity induced by mono-aminoethylamine substitution on the primary rim of β-cyclodextrin, was considered to be a key factor according to NMR spectroscopy and molecular modeling studies. The ciprofloxacin with mono-6-deoxy-6-aminoethylamino-β-cyclodextrin complex was characterized using FE-SEM, DSC, FT-IR, T1 relaxation, 2D NOESY, and DOSY NMR spectroscopy and molecular modeling studies. The solubility property of ciprofloxacin complexed with mono-6-deoxy-6-aminoethylamino-β-cyclodextrin was enhanced by seven-fold compared to that of pure ciprofloxacin. Furthermore antibacterial activity of that complex against methicillin-resistant <I>Staphylococcus aureus</I> was enhanced and it clearly showed the growth inhibition. The mono-6-deoxy-6-aminoethylamino-β-cyclodextrin has the potential to be utilized for other oblong guest molecules besides ciprofloxacin based on the novel induced elliptical cavity.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mono-6-deoxy-6-aminoethylamino-β-cyclodextrin (Et-β-CD) was synthesized. </LI> <LI> Oval-shaped cavity within Et-β-CD was induced by mono aminoethylamine substitution. </LI> <LI> Ciprofloxacin (CIP)/Et-β-CD complex was thoroughly characterized. </LI> <LI> CIP/Et-β-CD complex effectively enhanced the bioavailability and solubility of CIP. </LI> </UL> </P>
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Change of Surviving Fractions based on the Recovery of Potentially Lethal Damage in HFL-I Cell Line
Eunae Choi 한국방사선학회 2017 한국방사선학회 논문지 Vol.11 No.3
Potentially lethal damage repair (PLDR) in HFL-I was investigated by delayed plating experiments. The surviving fraction data were fitted to the linear Quadratic equation (LogSn=-nγ(αd+βd2) where γ=1 for immediate plating). And a repair factor γ was developed to compare survival for immediate and delayed plating . When we only took into account the repair factor of PLDR γ which was derived from the delay assay, the cell survival response th fractionated carbon ion irradiation was not fully matched. This gap suggested that consideration of another repair process is necessary. So this suggests that the various repair process plays an important role in the fractionated irradiations.
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Choi, Jae Min,Cho, Eunae,Lee, Benel,Jeong, Daham,Choi, Youngjin,Yu, Jae-Hyuk,Jung, Seunho Elsevier 2016 Carbohydrate polymers Vol.151 No.-
<P><B>Abstract</B></P> <P>The aryl hydrocarbon receptor (AhR) is a ligand activated transcriptional regulator, which governs key biological processes including detoxification of carcinogens. β-Naphthoflavone (β-NF) is a non-toxic flavonoid, and a potent AhR agonist. Thus, β-NF can induce the representative detoxifying enzyme cytochrome P4501A1, thereby enhancing the detoxification potential. However, its low water solubility hampers the use. We found that supramolecular complexation of β-NF with the synthetic 6,6′-thiobis(methylene)-β-cyclodextrin (β-CD-S) dimer significantly enhanced β-NF’s role as an AhR agonist. The water solubility of β-NF was increased to 469 fold by effective supramolecular complexation with the β-CD-S dimer, and caused significant induction of cytochrome P4501A1. Stable formation of the supramolecular complex of β-NF with β-CD-S-dimer was verified by various analyses. In summary, supramolecular complexation of β-NF with β-CD-S dimer greatly enhanced bio-availability of β-NF as an AhR agonist. Our findings provide an easy, non-destructive, and alternative approach to enhance the bio-availability of therapeutics.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 6, 6′-Thiobis(methylene)-β-cyclodextrin dimer (β-CD-S-dimer) was synthesized. </LI> <LI> The β-CD-S-dimer was used to enhance β-naphthoflavone’s water solubility. </LI> <LI> The solubilized β-NF by complexation significantly induced the cytochrome P4501A1 activity. </LI> <LI> β-NF supramolecular complex with β-CD-S-dimer enhanced the bio-functionality of β-NF. </LI> <LI> Various instrumental analyses were performed to verify the formation of a supramolecular complex. </LI> </UL> </P>
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Eunae Choi,Jun-Im Song 한국동물분류학회 2015 Animal Systematics, Evolution and Diversity Vol.31 No.3
Two scleractinian species are newly recorded in Korea: Leptoseris mycetoseroides Wells, 1954 and Phyllangia hayamaensis (Eguchi, 1968). The two genera Leptoseris Milne Edwards and Haime, 1849 and Phyllangia Milne Edwards and Haime, 1848 are also newly recorded in Korea. The specimens were collected from the subtidal zones of Jeju-do Island, Korea by SCUBA diving from 1991 to 2007. Leptoseris mycetoseroides is characterized by its platelike growth form, intratentacular budding, irregularly developed collines, single styliform columella, and even septa and septocostae. Phyllangia hayamaensis is distinguished by its encrusting and plocoid growth form of corallites basally united with common coenosteum, trabecular columella, and irregular septal arrangements and paliform lobes.
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