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RISS 인기검색어
- 검색키워드
- 저자 : Emad M. Kassem (검색결과 2 건)
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Emad M. Kassem,Howaida I. Abd-Alla,Eslam R. El-Sawy,Adel H. Mandour,Dina Abdel-Mogeed,Mounir M. El-Safty 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.6
A series of fused pyranopyrazole and pyranoimidazole, namely 5-(3,6-diamino-4-aryl-5-carbonitrile-pyrano(2,3-c)pyrazol-2-yl)sulphonyl-8-hydroxyquinolines (5a-e), 5-(6-amino-4-aryl-5-carbonitrile-pyrano(2,3-c)pyrazol-3-yl)sulphonamido-8-hydroxyquinolines (6a-e), 5-(2-thioxo-4-aryl-5-carbonitrile-6-amino-pyrano(2,3-d)imidazol-2-yl)sulphonyl-8-hydroxyquinolines (10a-e), and 5-(2-oxo-4-aryl-5-carbonitrile-6-amino-pyrano(2,3-d)imidazol-2-yl) sulphonyl-8-hydroxyquinolines (11a-e), have been prepared via condensation of some arylidine malononitriles with 5-sulphonamido-8-hydroxyquinoline derivatives 3, 4, 8 and 9. All the synthesized compounds were screened for their antimicrobial activities, and most of the tested compounds showed potent inhibition growth activity towards Escherichia coli, Pseudomonas aeruginosa (Gramnegative bacteria). Furthermore, six selected compounds were tested for their antiviral activity against avian paramyxovirus type1 (APMV-1) and laryngotracheitis virus (LTV), and the results showed that a concentration range of 3-4 μg per mL of compounds 2, 3, and 4 showed marked viral inhibitory activity for APMV-1 of 5000 tissue culture infected dose fifty (TCID50) and LTV of 500 TCID50 in Vero cell cultures based on their cytopathic effect. Chicken embryo experiments show that compounds 2, 3, and 4 possess high antiviral activity in vitro with an inhibitory concentration fifty (IC50) range of 3-4 μg per egg against avian APMV-1 and LTV and their toxic concentration fifty (CC50) of 200-300 μg per egg.
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An integral square error-based model predictive controller for two area load frequency control
Kassem, Ahmed M.,Sayed, Khairy,El-Zohri, Emad H.,Ali, Hossam H. Techno-Press 2017 Advances in energy research Vol.5 No.1
The main objective of load frequency control (LFC) is to keep the frequency value at nominal value and force deviation of the frequency to zero in case of load change. This paper suggests LFC by using a model predictive control (MPC), based on Integral Square Error (ISE) method designed to optimize the damping of oscillations in a two-area power system. The MPC is designed and simulated with a model system in state space, for robust performance in the system response. The proposed MPC is tuned by ISE to achieve superior efficiency. Moreover, its performance has been assessed and compared with the PI and PID conventional controllers. The settling time and overshoot with MPC are extremely minimized as compared with conventional controllers.
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