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        Thienobenzothiopyranones 111-New 4H-thieno[2,3-b][1]benzothiopyran-4-ones Carrying Different Heterocyclic Moieties of Expected Pharmacological Interest

        El-Subbagh, H.I.,El-Emam, A.A.,El-Ashmawy, M.B.,Shehata, I.A. The Pharmaceutical Society of Korea 1990 Archives of Pharmacal Research Vol.13 No.1

        Reaction of 2-formyl-4H-thieno [2, 3-b] benzothiopyran-4-one (1) with different heterocyclic amines afforded the corresponding Schiff's bases (2-4). Diethyl malonate, ethyl cyanoacetate and malononitrile were reached with 1 to afford compounds 5, 7 and 8, respectively. Compound 5 was cyclized to the pyrazolidin-3, 4-dione (6) by the action of hydrazine hydrate, whereas compound 7 was utilized for the synthesis of the thiazolin-4 one derivatives (9-13).

      • A Cost-Effective Land Surveying System for Engineering Applications

        El-Ashmawy, Khalid L.A. International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.11

        The field of land surveying is changing dramatically due to the way data is processed, analyzed and presented. Also, there is a growing demand for digital spatial information, coming primarily from the GIS (Geographical Information System) user community. Such a demand has created a strong development potential for a new land surveying software. An overview of the development and capabilities of a land surveying software platform based on the Windows system, SurveyingMap, is presented. Among its many features, SurveyingMap provides a lot of adaptability for networks adjustment, geodetic and plane coordinates transformation, contouring, sectioning, DTM (Digital Terrain Model) generation, and large scale mapping applications. The system output is compatible with well known computer aided drafting (CAD) /GIS packages to expand its scope of applications. SurveyingMap is also suitable for non-technical users due to the user-friendly graphic user interface. The system could be used in engineering, architecture, GIS, and academic teaching and research, among other fields. Two applications of SurveyingMap, extension of field control and large scale mapping, for the case study area are established. The results demonstrate that the system is adaptable and reasonably priced for use by college and university students.

      • An efficient C<sup>1</sup> beam element via multi-scale material adaptable shape function

        El-Ashmawy, A.M.,Xu, Yuanming Techno-Press 2022 Advances in nano research Vol.13 No.4

        Recently, promising structural technologies like multi-function, ultra-load bearing capacity and tailored structures have been put up for discussions. Finite Element (FE) modelling is probably the best-known option capable of treating these superior properties and multi-domain behavior structures. However, advanced materials such as Functionally Graded Material (FGM) and nanocomposites suffer from problems resulting from variable material properties, reinforcement aggregation and mesh generation. Motivated by these factors, this research proposes a unified shape function for FGM, nanocomposites, graded nanocomposites, in addition to traditional isotropic and orthotropic structural materials. It depends not only on element length but also on the beam's material properties and geometric characteristics. The systematic mathematical theory and FE formulations are based on the Timoshenko beam theory for beam structure. Furthermore, the introduced element achieves C1 degree of continuity. The model is proved to be convergent and free-off shear locking. Moreover, numerical results for static and free vibration analysis support the model accuracy and capabilities by validation with different references. The proposed technique overcomes the issue of continuous properties modelling of these promising materials without discarding older ones. Therefore, introduced benchmark improvements on the FE old concept could be extended to help the development of new software features to confront the rapid progress of structural materials.

      • Numerical investigations of reinforcement concrete beams with different types of FRP bars

        Azza M. Al-Ashmawy,Osman Shallan,Tharwat A. Sakr,Hanaa E. Abd-EL-Mottaleb 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.88 No.6

        The present study is focused on instigation of the nonlinear mechanical behavior of reinforced concrete beams considering different types of FRP bars through nonlinear finite element simulations. To explore the impact of the FRP reinforcement type and geometry on the nonlinear mechanical behavior of reinforced beam, intensive parametric studies are carried out and discussed. Twenty models were carried out based on the finite element software (ABAQUS). The concrete damage plasticity model was considered. Four types of fiber polymer bars, CFRP, GFRP, AFRP and BFRP as longitudinal reinforcement for concrete beam were used. The validation of numerical results was confirmed by experimental as well as numerical results, then the parametric study was conducted to evaluate the effect of change in different parameters, such as bar diameter size, type of FRP bars and shear span length. All results were analyzed and discussed through, load-deflection diagram. The results showed that the use of FRP bars in rebar concrete beam improves the beam stiffness and enhance the ultimate load capacity. The load capacity enhanced in the range of (20.44-244.47%) when using different types of FRP bars. The load-carrying capacity of beams reinforced with CFRP is the highest one, beams reinforced with AFRP is higher than that reinforced with BFRP but beams reinforced with GFRP recorded the lowest load of capacity compered with other beams reinforced with FRP Bars.

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        EFFECTS OF XYLAZINE (ALPHA 2-ADRENERGIC AGONIST) ON THE STRESS RESPONSE TO IMMOBILIZATION AND HEAT IN RATS

        Fayed, A.H.,Zakaria, A.D.,Hedaya, S.A.,El-Ashmawy, I.M. Asian Australasian Association of Animal Productio 1994 Animal Bioscience Vol.7 No.3

        The effect of xylazine administration on plasma cortisol, prolactin, glucose and packed cell volume (PCV) responses to immobilization and heat stress was investigated. Immobilization of rats for 2 hours by ligation of the fore and hind legs strongly caused approximately two-fold increase in plasma cortisol and prolactin levels. Plasma glucose and PCV were not significantly changed. Pretreatment of immobilized rats with xylazine (20 mg/kg body weight i.m.) resulted in approximately 20% reduction in both plasma cortisol and prolactin concentrations. A marked hyperglycemia and increase in the PCV value was observed. On the other hand, rats exposed to acute heat stress ($40^{\circ}C$, and 60% relative humidity) for 2 hours, also developed two fold increase in both plasma cortisol and prolactin concentrations and the pretreatment with xylazine caused a 20% reduction in the levels of both hormones. Plasma glucose level was not significantly changed in heat stressed rats but it was markedly increased after pretreatment with xylazine. PCV was significantly incrcased under heat stress and pretreatment with xylazine induced a pronounced elevation in this value. It was suggested that stimulation of cortisol and prolactin secretion in response to immobilization or heat stress can be partially reduced by an alpha 2-adrenergic agonist.

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