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- 저자 : Donos, Aristomenis (검색결과 9 건)
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Banks, Elliot,Donos, Aristomenis,Gauntlett, Jerome P.,Griffin, Tom,Melgar, Luis American Physical Society 2017 Physical Review D Vol.95 No.2
<P>We study the thermal transport properties of general conformal field theories (CFTs) on curved spacetimes in the leading order viscous hydrodynamic limit. At the level of linear response, we show that the thermal transport is governed by a system of forced linearized Navier-Stokes equations on a curved space. Our setup includes CFTs in flat spacetime that have been deformed by spatially dependent and periodic local temperature variations or strains that have been applied to the CFT, and hence is relevant to CFTs arising in condensed matter systems at zero charge density. We provide specific examples of deformations which lead to thermal backflow driven by a dc source: that is, the thermal currents locally flow in the opposite direction to the applied dc thermal source. We also consider thermal transport for relativistic quantum field theories that are not conformally invariant.</P>
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Holographic thermal DC response in the hydrodynamic limit
Banks, Elliot,Donos, Aristomenis,Gauntlett, Jerome P,Griffin, Tom,Melgar, Luis Institute of Physics 2017 Classical and quantum gravity Vol.34 No.4
<P>We consider black hole solutions of Einstein gravity that describe deformations of CFTs at finite temperature in which spatial translations have been broken explicitly. We focus on deformations that are periodic in the non-compact spatial directions, which effectively corresponds to considering the CFT on a spatial torus with a non-trivial metric. We apply a DC thermal gradient and show that in a hydrodynamic limit the linearised, local thermal currents can be determined by solving linearised, forced Navier–Stokes equations for an incompressible fluid on the torus. We also show how sub-leading corrections to the thermal current can be calculated as well as showing how the full stress tensor response that is generated by the DC source can be obtained. We also compare our results with the fluid-gravity approach.</P>
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A procedure for identifying stem cell compartments with multi-lineage differentiation potential
Amin, Harsh D.,Olsen, Irwin,Knowles, Jonathan,Donos, Nikolaos Royal Society of Chemistry 2011 The Analyst Vol.136 No.7
<P>Stem cells isolated from adult human tissue have received increasing attention because of their potential to repair and/or regenerate damaged tissue. However, identification and characterization of such cell populations have been limited due to the lack of adequate methodology for assessing their multi-lineage potential. In the present study, using adult human ligament tissue as a model, we have developed a combination of methods which together can be used to identify adult stem cell compartments based on their ability to undergo a range of differentiation pathways, including osteogenesis, adipogenesis, chondrogenesis, myogenesis, vasculogenesis, angiogenesis, neurogenesis and gliogenesis <I>in vitro</I>. This was carried out using the conventional reverse transcription polymerase chain reaction technique to assess the expression of selected key lineage-associated marker genes and by using histological, immunological and morphological criteria to assess characteristic features of lineage-specific ‘terminal’ differentiation <I>in vitro</I>.</P> <P>Graphic Abstract</P><P>A new method was developed to identify adult human stem cell compartments based on their range of osteogenenic adipogenenic, chondrogenenic, myogenenic, vasculogenenic, angiogenenic, neurogenenic and gliogenenic differentiation capabilities <I>in vitro</I>. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0an00816h'> </P>
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Gut microbiome and neurocritically ill patients
Dono Antonio,Esquenazi Yoshua,Choi Huimahn Alex 대한신경집중치료학회 2022 대한신경집중치료학회지 Vol.15 No.1
Since the times of Rokitansky and Cushing, we have been fascinated by the connections between the gut and the brain. Recent advances in next-generation sequencing techniques have shown that this relationship is even more complex and integral to our sense of self than previously imagined. As these techniques refine our understanding of the abundance and diversity of the gut bacterial microbiome, the relationship between the gut and the brain has been redefined. Now, this is understood as a complex symbiotic network with bidirectional communication, the gut-brain axis. The implication of this communication involves an intense focus of research on a variety of chronic psychiatric, neurological, neurodegenerative, and neuro-oncological diseases. Recently, the gut-brain axis has been studied in neurologically ill patients requiring intensive care. Preliminary studies have shown that acute brain injury changes the bacterial phenotype from one that is symbiotic with the host human to one that is pathologic, termed the “pathobiome.” This can contribute to nosocomial pneumonia and sepsis. The first studies in neurologically ill patients in the neurointensive care unit (NeuroICU) demonstrated changes in the gut microbiome between neuroICU patients and healthy matched subjects. Specifically, a decrease in short-chain fatty acid-producing bacteria and increase in harmful gut microbes have been associated with mortality and decreased function at discharge. Although these preliminary findings are exciting and have opened a new field of research in the complex NeuroICU population, there are several limitations and challenges. Further investigation is needed to confirm these correlations and understand their implications on patients in a complex intensive care environment.
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Sulistiadi Dono Iskandar 연세대학교 빈곤문제국제개발연구원 2021 Asian Development Perspectives (ADP) Vol.12 No.2
How the ability of children determines the allocation of investment between siblings has raised the interest of many in development economics. However, attention has not been paid to the possibility of distinct behavior between poor and non-poor parents. Using Raven’s colored progressive matrices (CPM) as a direct measurement of child cognitive abilities, we examine differences in educational investment decisions between poor and non-poor parents in Indonesia. Our results suggest that poor parents tend to reduce the gap between their children, with having a smarter sibling being associated with the increase in the likelihood of being enrolled by around 3.2-3.5% for a poor child. On the other hand, non-poor parents tend to reinforce the gap that exists between their children. We also find that non-poor parents tend to discriminate between their non-biological children, in which their schooling outcome is conditional on their ability; while for biological children, the schooling outcome seems to be independent of their ability.
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Khudanov, Bakhtinur,Jung, Hoi In,Kahharova, Dono,Lee, Jeong-Woo,Hamidov, Ilhom,Lee, Eun-Song,Kim, Baek-Il Elsevier 2018 Photodiagnosis and photodynamic therapy Vol.21 No.-
<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>The aim of this study was to determine whether an oral health education program using a Qscan device based on quantitative light-induced fluorescence (QLF) technology could improve the oral hygiene status and oral health literacy of adolescents.</P> <P><B>Materials and methods</B></P> <P>One hundred adolescents aged 14–16 years attending a school in Tashkent city were included in this study. The participants were assigned to the following two groups using permuted block randomization technique: (i) control group (traditional learning) and (ii) experimental group (Qscan device-based learning). The participants included in the experimental group received additional education and training on dental plaque removal using the Qscan device. The accumulated levels of plaque were assessed in all participants, who also completed questionnaires about their oral health status, oral health knowledge, attitude, and behavior during an 8-week period.</P> <P><B>Results</B></P> <P>There were statistically significant improvements in the experimental group compared to the control group in the plaque index (0.46 vs 0.07, <I>p </I>< .05), oral health knowledge (19.4 vs 28.8, <I>p </I>< .05), attitude (16.7 vs 20.2, <I>p </I>< .05), and behavior (19.9 vs 30.5, <I>p </I>< .05).</P> <P><B>Conclusions</B></P> <P>This study has demonstrated that an oral health education program based on the use of QLF technology could be useful for improving the oral hygiene status and oral health literacy of adolescents in Uzbekistan.</P> <P><B>Highlights</B></P> <P> <UL> <LI> QLF technology could be used to motivate students to improve their oral health and enlarge the learning effects. </LI> <LI> Oral health education including the use of QLF technology is effective in improving the oral health knowledge and oral hygiene status of adolescents. </LI> <LI> QLF technology in a oral health education program was useful for improving the oral hygiene status and oral health literacy. </LI> </UL> </P>
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