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RISS 인기검색어
- 검색키워드
- 저자 : Ding Jiyong (검색결과 4 건)
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Biomechanical Mechanism of Fabric Softness Discrimination
Hu, Jiyong,Ding, Xin,Wang, Rubin The Korean Fiber Society 2007 Fibers and polymers Vol.8 No.4
"Softness" is one of the primitive terms describing the physical and sensory attributes of fabric, however, the information for its physiological mechanism compared to statistical physical factors of fabric softness is scarce. To explain the biomechanical and the potential neurophysiological phenomenon for exploring fabric softness, a finger-fabric finite element model is used to conduct an active contact simulation analysis. The effects of surface friction index and compression modulus of fabric on softness discrimination are investigated. The interests of the study are in the contributions of these fabric variables to the changing contact area, interfacial fiction shear stress and contact pressure distributions, which are significant cognitive variables or stimulus parameters in peripheral neural levels documented by prior observations. The mechanistic data for fingerpad-fabric interaction indicate that the basis for the perception of softness of flexible and bulk fabric is likely on the spatial variation of the pressure and shear stress on the skin resulting from the surface friction index and compression property of fabric. These conclusions suggest that devices for the haptic rendering of fabric softness, based on vibration result from surface roughness, is not sufficient to perceive the soft-touch feel of fabric as a result of the cues with lack information for the changing contact area by touch.
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An Xiaowei,Li Huimin,Omoleye Ojuri,Wang Zhuofu,Ding Jiyong 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.7
Design optimization is an effective strategy to reduce construction project costs. This study focuses on the benefit of designoptimization, which should be allocated to the designer. Furthermore, the distribution ratio can be determined through negotiation. Inline with this view, this paper initially analyzed the benefits of engineering design optimization and the basic mechanism of itsdistribution. Second, we established the negotiation model of design optimization profit distribution by considering the fairnessconcern behavior of subjects. Finally, we set up the following three experimental scenarios: the designer solely has fairness concernbehavior, the owner exclusively has fairness concern behavior, and both negotiators have fairness concern behavior. From theengineering projects perspectives, we further analyzed the effects of the fairness concerns of both negotiators in terms of engineeringdesign optimization and negotiation performance using negotiation simulation experiments. Our experimental scenarios results showthat the appropriate behavior of fairness concerns by the two negotiators is valuable in improving their own advantages. However,excessive attention to the behaviors of fairness concerns by the two negotiators may lead to an increase in the negotiation cycle,which is not beneficial in attaining optimization. This study aims to provide references for the construction project management.
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Surface Modification with Pluronic P123 Enhances Transfection Efficiency of PAMAM Dendrimer
Xiang Wang,Shen Gao,Xin Wu,Wei Fan,Baoyue Ding,Xiaoyu Wang,Wei Zhang,Xueying Ding,Jing Gao,Quangang Zhu,Jiyong Liu,Zhen Cai 한국고분자학회 2012 Macromolecular Research Vol.20 No.2
To improve gene delivery efficiency and decrease cytotoxicity of polyamidoamine (PAMAM) polymers,P123-g-PAMAM was synthesized by modifying PAMAM with pluronic P123. The structure of the synthesized polymers was analyzed using proton nuclear magnetic resonance. The polymers were able to self-assemble with DNA,forming nanometer-scale complexes. Particle size measurement confirmed that the mean diameter of the polyplexes was 100-250 nm. The cytotoxicity and transfer efficiency were measured and compared with those of PEI and PAMAM. All of the polyplexes showed significantly low cytotoxicity in the MCF-7, HepG2, and 293T cell lines. In addition, the low level of P123 grafting to PAMAM showed significantly higher transfection efficiency than unmodified PAMAM at the optimal N/P ratio. These results suggest that P123-ylated PAMAM may prove as a useful carrier for gene delivery.
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A Small-Molecule Antagonist of the Hedgehog Signaling Pathway
Lee, Jongkook,Wu, Xu,Pasca di Magliano, Marina,Peters, Eric C.,Wang, Yan,Hong, Jiyong,Hebrok, Metthias,Ding, Sheng,Cho, Charles Y.,Schultz, Peter G. Wiley-VCH Verlag 2007 Chembiochem Vol. No.
<B>Graphic Abstract</B> <P>Shadow the Hedgehog. JK184 (illustrated in the scheme) was identified as an antagonist of Hedgehog signaling through a cell-based screen of chemical libraries. Results from biochemical and cellular experiments suggest that JK184 functions by inhibiting class IV alcohol dehydrogenase. This molecule should serve as a useful tool for studying Hedgehog signaling. <img src='wiley_img/14394227-2007-8-16-CBIC200700403-content.gif' alt='wiley_img/14394227-2007-8-16-CBIC200700403-content'> </P>
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