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- 검색키워드
- 저자 : Costa Patrícia M. (검색결과 4 건)
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Isabel F. Almeida,Eduarda Fernandes,José L.F.C. Lima,Patrícia Valentão,Paula B. Andrade,Rosa M. Seabra,P.C. Costa,M.F. Bahia 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.1
Eucalyptus globulus Labill. (Family Myrtaceae) is a plant of Australian origin, with a reported therapeutic use in airway inflammatory diseases. Considering that reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in the pathogenesis of airway inflammatory diseases such as asthma and chronic obstructive pulmonary disease, an effective scavenging activity against these reactive species may contribute for the therapeutic effect of this plant. In the present study, a water extract of E. globulus leaves was evaluated for its putative in vitro scavenging effects on ROS (HO·, O2·−, ROO·, and H2O2) and RNS (·NO and ONOO−) and on 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). Qualitative and quantitative analyses of the extract's phenolic composition were also performed. The Eucalyptus leaf water extract presented a remarkable capacity to scavenge all the reactive species tested, with all the 50% inhibitory concentrations being found at the μg/mL level. Phytochemical analysis showed the presence of polyphenols such as flavonoids (rutin and quercitrin) and phenolic acids (chlorogenic acid and ellagic acid), which may be partially responsible for the observed antioxidant activity. These observations provide further support, beyond the well-known antibacterial and antiviral activities of the Eucalyptus plant, for its reported use in traditional medicine such as in the treatment of airway inflammatory diseases, considering the important role of ROS and RNS in the inflammatory process, although further studies are needed to prove the bioavailability of the antioxidants/antibacterial compounds of the extract as well as the ability of the active compounds to reach specific tissues and to act in them.
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Mata Ribeiro Luís,Meireles Rita P.,Brito Irís M.,Costa Patrícia M.,Rebelo Marco A.,Barbosa Rui F.,Choupina Miguel P.,Pinho Carlos J.,Ribeiro Matilde P. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.1
Background Implant-based breast reconstruction has evolved tremendously in the last decades, mainly due to the development of new products and techniques that make the procedure safer and more reliable. The purpose of this study was to compare the outcomes in immediate one-stage breast reconstruction between acellular dermal matrix (ADM) and inferior dermal flap (IDF).Methods We conducted a retrospective comparative study of patients submitted to immediate breast reconstructions with an anatomical implant and ADM or IDF in a single center between 2016 and 2018. Outcomes evaluated included major complications, early complications, reinterventions, readmissions, and reconstruction failure. Simple descriptive statistics and univariate analysis were performed.Results A total of 118 breast reconstructions (85 patients) were included in the analysis. Patients in the IDF group had a higher body mass index (median = 27.0) than patients in the ADM group (median = 24). There were no statistically significant differences among both groups regarding immediate major complication, early complications, readmissions, and reinterventions.Conclusion There are no significant differences in complications between the ADM and IDF approach to immediate implant breast reconstruction. In patients with higher body mass index and large, ptotic breasts, we recommend an immediate implant reconstruction with IDF.
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Mata Ribeiro Luís,Meireles Rita P.,Brito Irís M.,Costa Patrícia M.,Rebelo Marco A.,Barbosa Rui F.,Choupina Miguel P.,Pinho Carlos J.,Ribeiro Matilde P. 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.2
Background Implant-based breast reconstruction has evolved tremendously in the last decades, mainly due to the development of new products and techniques that make the procedure safer and more reliable. The purpose of this study was to compare the outcomes in immediate one-stage breast reconstruction between acellular dermal matrix (ADM) and inferior dermal flap (IDF).Methods We conducted a retrospective comparative study of patients submitted to immediate breast reconstructions with an anatomical implant and ADM or IDF in a single center between 2016 and 2018. Outcomes evaluated included major complications, early complications, reinterventions, readmissions, and reconstruction failure. Simple descriptive statistics and univariate analysis were performed.Results A total of 118 breast reconstructions (85 patients) were included in the analysis. Patients in the IDF group had a higher body mass index (median = 27.0) than patients in the ADM group (median = 24). There were no statistically significant differences among both groups regarding immediate major complication, early complications, readmissions, and reinterventions.Conclusion There are no significant differences in complications between the ADM and IDF approach to immediate implant breast reconstruction. In patients with higher body mass index and large, ptotic breasts, we recommend an immediate implant reconstruction with IDF.
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Virginia D. Kappel,Geison M. Costa,Gustavo Scola,Francilene A. Silva,Melissa F. Landell,Patr?cia Valente,Daiana G. Souza,Danielli C. Vanz,Fl?vio H. Reginatto,Jos? C.F. Moreira 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.2
The phenolic content, antioxidant potential, and antimicrobial activity of extracts of different parts of the fruitfrom Capsicum baccatumL. var. pendulumwere investigated. The analysis of phenolic content was performed by the Folin-Ciocalteu method and reversed-phase high-performance liquid chromatography. The in vitroantioxidant activity was assessedby the total reactive antioxidant potential and total antioxidant reactivity index. The antioxidant activity was positively cor-related with the amount of phenolics found in each sample. The ex vivoantioxidant potential was assessed using the rat liverslice model. The antimicrobial activity was screened using Gram-positive and Gram-negative bacteria and fungi. All the ex-tracts revealed antioxidant activity and a weak antimicrobial activity.
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