소양정의 시문과 춘천문화

오춘택(Oh Chun-Taek) 한림대학교 아시아문화연구소 2002 아시아문화 Vol.- No.18

초소형 구조물의 부착 방지를 위한 새로운 자기 집합 물질에 대한 연구

김봉환,오창훈,전국진,정택동,변장웅,이윤식 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

In order to achieve stiction-free polysilicon surfaces, we have suggested a new chemical grafting precursor and confirmed their excellent characteristics. When dichlorodimethylsilane(DDS, C_(2)H_(6)SiCl_(2)), a dialkyldichlorosilane widely used in silicon machining, have been used as a precursor, experimental results were clearly comparable to those of monoalkyltrichlorosilanes octadecyltrichlorosilane (OTS, C_(18)H_(37)SiCl_(3)) or 1H,1H,2H,2H-perfluorodecyltrichloro-silane (FDTS, C_(10)H_(4)F_(17)SiCl_(3)) in terms of stiction reduction. The polysilicon cantilevers were fabricated in the carefully controlled conditions and laser interferometer indicated that their residual stress gradient was 2 MPa/μm upward from the substrate. The SEM images of polysilicon cantilever beams with DDS coating are upward and no stiction is observed up to 2 mm in length.

Novel drug combination for <i>Mycobacterium abscessus</i> disease therapy identified in a <i>Drosophila</i> infection model

Oh, Chun-Taek,Moon, Cheol,Park, Ok Kyu,Kwon, Seung-Hae,Jang, Jichan Oxford University Press 2014 The Journal of antimicrobial chemotherapy Vol.69 No.6

<P><B>Objectives</B></P><P><I>Mycobacterium abscessus</I> is known to be the most drug-resistant <I>Mycobacterium</I> and accounts for ∼80% of pulmonary infections caused by rapidly growing mycobacteria. This study reports a new <I>Drosophila melanogaster</I>–<I>M. abscessus</I> infection model that can be used as an <I>in vivo</I> efficacy model for anti-<I>M. abscessus</I> drug potency assessment.</P><P><B>Methods</B></P><P><I>D. melanogaster</I> were challenged with <I>M. abscessus</I>, and infected flies were fed with a fly medium containing tigecycline, clarithromycin, linezolid, clofazimine, moxifloxacin, amikacin, cefoxitin, dinitrobenzamide or metronidazole at different concentrations (0, 100 and 500 mg/L). The survival rates of infected flies were plotted and bacterial colonization/dissemination in fly bodies was monitored by cfu determination and green fluorescent protein epifluorescence.</P><P><B>Results</B></P><P>The <I>D. melanogaster</I>–<I>M. abscessus</I> model enabled an assessment of the effectiveness of antibiotic treatment. Tigecycline was the best drug for extending the lifespan of <I>M. abscessus</I>-infected <I>Drosophila</I>, followed by clarithromycin and linezolid. Several different combinations of tigecycline, linezolid and clarithromycin were tested to determine the best combination. Tigecycline (25 mg/L) plus linezolid (500 mg/L) was the best drug combination and its efficacy was superior to conventional regimens, not only in prolonging infected fly survival but also against <I>M. abscessus</I> colonization and dissemination.</P><P><B>Conclusions</B></P><P>This <I>D. melanogaster</I>–<I>M. abscessus</I> infection/curing methodology may be useful for the rapid evaluation of potential drug candidates. In addition, new combinations using tigecycline and linezolid should be considered as possible next-generation combination therapies to be assessed in higher organisms.</P>

18세기의 소설비평 -<창선감의록> <사씨남정기> <구운몽> <춘향전>을 중심으로-

오춘택 ( Chun Taek Oh ) 민족어문학회 2011 어문논집 Vol.- No.64

17세기 말에 조성기는 유가의 이념을 구현하기 위하여 <창선감의록>이라는 소설 양식을 택하였다. 김만중은 군신의 관계를 <사씨남정기>로 이야기하였으며, 파쟁에서 비롯된 갈등을 <구운몽>을 통하여 자기성찰로 승화시켰다. <춘향전>은 어려운 시대의 독서대중에게 꿈과 감동을 심어주었다. 18세기 <창선감의록>의 논평은 이 작품의 밑바탕에 맹자의 성선설이 깔려 있다고 보았다. <사씨남정기>의 경우는 굴원의 <이소>에 근거를 두고 군왕을 축으로 하는 신하들의 파쟁에서 충신은 끊임없이 참고 용서해야만 갈등을 해결할 수 있다는 윤리관으로 해석하였다. 영조는 <구운몽>을 극찬하였는데, 그 이유로 김만중이 육관대사의 가르침을 통하여 당쟁과 유배로 점철된 자신의 처신을 반성하고 스스로 성찰하였다고 보았다. 유진한은 한시 <춘향가>를 통하여 <춘향전>의 후반부를 극대화함으로써 독자들의 억눌린 감정을 풀어주는 역할을 강조하였다.

潘碩枰 論

吳春澤(Oh Chun-taek) 한림대학교 아시아문화연구소 1989 아시아문화 Vol.- No.5

ON THE COMPARISON OF MISSING-CELL ESTIMATES IN THE DESIGNED EXPERIMENTS

Oh, Jong Chul,Lee, Jang Taek,Kim, Byung Chun 단국대학교 통계문제연구소 1988 數學 및 統計硏究 Vol.16 No.-

The extension of Murray's (1988) results for the randomized block design is proposed for the three-way factorial design with one missing observation. The results of this paper show that the classical missing-cell estimate used in the three-way factorial design is unbiased but does not have minimum variance when one or more of factors are considered random. In addition, the alternative unbiased missing-cell estimate of having smaller variance than classical estimate are given.

Ginsenoside Rk1 Induces Apoptosis in Neuroblastoma Cells Through Loss of Mitochondrial Membrane Potential and Activation of Caspases

Oh, Jung-Mi,Lee, Jeongwoo,Im, Wan-Taek,Chun, Sungkun MDPI 2019 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.20 No.5

<P>Neuroblastoma (NB) is the most common childhood cancer, with a very poor prognosis. More than 60% of children with NB die within five years; therefore, a more effective therapy for NB is required. Although ginsenoside has been shown to significantly inhibit the growth of various cancers, the effect of ginsenoside Rk1 on neuroblastoma has not been known yet. Hence, we examined the anticancer effects of highly pure Rk1 on neuroblastoma cell lines. The apoptotic effects of Rk1 on neuroblastoma cells were examined using cell viability assay, flow cytometry and cell staining assay, and the change in gene expression levels were analysed using RT-PCR, western blots, and immunohistochemistry. The metastatic effect of Rk1 was monitored by wound healing assay, invasion and migration with Matrigels. Rk1 inhibited neuroblastoma cell viability dose-dependently. Rk1-induced apoptosis was investigated through nuclear condensation and mitochondrial membrane potential loss, and it showed that Rk1 can induce cell cycle arrest at the G0/G1 phase but also inhibit the metastatic ability of neuroblastoma cells. Moreover, Rk1 (30 mg/kg) injections markedly inhibited xenograft tumor growth. These findings demonstrate that Rk1 might be valuable in the development of anti-cancer agents for neuroblastoma treatment. </P>

반사파 흡수필터를 이용한 불규칙 파랑 재현 방법

전인식,오영민,정신택 한국해안해양공학회 1989 학술강연회 발표논문초록집 Vol.1 No.1

한국인 태권도 수련자와 중국인 무술 수련자의 사회성발달에 관한 연구

최춘산 ( Chun Shan Cui ),곽택용 ( Taek Yong Kwak ),오인호 ( In Hoo Oh ) 대한무도학회 2010 대한무도학회지 Vol.12 No.1

본 연구는 한국 태권도 수련자와 중국 무술 수련자를 대상으로 사회성발달을 규명함으로써 사회성발달의 하위요인인 활동성, 사교성, 안정성, 지배성, 자율성이 유의한 차이를 나타내고 있는 지를 규명하고자 하는데 연구의 목적을 두고 있다. 구체적으로 한국 태권도 수련자와 중국 무술 수련자의 사회성발달의 차이를 규명하기 위하여 태권도 수련자와 무술 수련자를 모 집단으로 선정한 후 한국 Y대학교(100명), H대학교(100명), K대학교(100명)에서 태권도를 수련하고, 중국 B대학(300명)에서 무술을 수련하는 수련자를 대상으로 각 학교 300명씩 총 600명을 편의표집법으로 표집 하였으며 응답이 불성실하다고 판단되거나, 기입누락 등과 같이 연구 자료로 부적합한 설문지를 제외하였으며, 최종분석에 사용된 표본은 589명이었다. 유효 표본은 SPSS WIN 15.0을 사용하여 빈도분석, 탐색적 요인분석, 신뢰도 분석, 독립표본 t-test를 실시하여 다음과 같은 결론을 도출하였다. 한국 태권도 수련자와 중국 무술자의 사회성발달은 차이가 있었다. 구체적으로 사교성, 지배성에서 유의한 차이가 있는 것으로 나타났으며, 태권도 수련자의 사회성이 무술수련자의 사회성보다 높은 것으로 나타났다. The aim of this study was to verify meaningful differences in the development of sociability between Korean (taekwondo) and Chinese (wushu) marital art practitioners. To do so, it looked at sub-categories of the development of sociability such as playfulness, amicability, stability, dominance, and autonomy. This study initially sampled 300 taekwondo practitioners from Y University(100), H University(100), K University(100) in Korea and 300 wushu practitioners from B University(300) in China. A total of 589 questionnaires were used for the analysis as the 11 samples deem inappropriate. Statistical methods which include frequency analysis, exploratory factor analysis, reliability analysis, and independent samples t-test were conducted using SPSS WIN 15.0 version. The results indicated that there existed significant differences between Korean and Chinese martial art practitioners. More specifically, meaningful differences were found in amicability, playfulness and dominance factors. Overall, the results implied that taekwondo practitioners were more sociable than wushu practitioners.

US-Originated Strain of Porcine Deltacoronavirus Outbreaks in South Korea, 2014~2016

Woo-Taek Oh,Hee-chun Chung,Hye-jung Yang,Jung-ah Kim,Bong-kyun Park 대한수의학회 2016 대한수의학회 학술대회발표집 Vol.2016 No.-