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Lai, Chi-Chun,Wang, Nan-Kai,Wu, Wei-Chi,Yeung, Ling,Hwang, Yih-Shiou,Chen, Kuan-Jen,Chen, Tun-Lu,Chuang, Lan-Hsin Informa Healthcare 2011 Cutaneous and ocular toxicology Vol.30 No.4
<P><I>Purpose</I>: To compare the long-term anatomical and visual outcomes of patients with idiopathic epiretinal membrane (ERM) removed by vitrectomy and membrane peeling with or without the use of intravitreal injection of triamcinolone acetonide (IVTA).</P><P><I>Methods</I>: A retrospective chart review was performed. Subjects who underwent vitrectomy and who were followed over 12 months were included. The study included two groups of patients. In group 1 (71 eyes), the patients underwent vitrectomy and membrane peeling without the use of IVTA. In group 2 (27 eyes), 2 mg of IVTA was given at the end of the surgery. The main outcome measures were best-corrected visual acuity (BCVA), central foveal thickness (CFT) determined by optical coherence tomography (OCT), the number of cataract surgeries, and the use of anti-glaucomatous drugs during the follow-up period.</P><P><I>Results</I>: This study included 98 eyes with ERM from 98 patients. There was no significant difference between the two groups with respect to age, gender, pre- and postoperative lens status, BCVA, CFT, or length of the follow-up period. The mean age for all of the patients was 62.45 ± 10.01 (mean ± SD) years, and the mean follow-up length was 20.58 ± 9.64 (mean ± SD) months. In all cases, the mean best-corrected logarithm of minimum angle of resolution (logMAR) acuity improved from a preoperative value of 0.91 ± 0.32 [Snellen equivalent (SE), 0.16 ± 0.14] to a postoperative value of 0.46 ± 0.36 (SE, 0.46 ± 0.29) (<I>P</I> < 0.0001). The CFT was reduced from a preoperative value of 473.46 ± 96.91 μm to a postoperative value of 302.44 ± 69.80 μm (<I>P</I> < 0.0001). Six patients (22.2%) in group 2 required anti-glaucomatous drugs to control intraocular pressure (IOP) during the follow-up period, and three patients (4.2%) in group 1 required drugs to control IOP (<I>P</I> == 0.012).</P><P><I>Conclusions</I>: The postoperative visual outcomes for patients with idiopathic ERM were favorable, but CFT did not return to a normal level, even in eyes in which 2 mg IVTA was used. The IVTA use after ERM removal produced no significant benefits during long-term follow-up, but IVTA did increase the risk of increased IOP.</P>
Tsung-Hua Lu(Tsung-Hua Lu),Shih-Hsien Lin(Shih-Hsien Lin),Mei Hung Chi(Mei Hung Chi),Ching-Lin Chu(Ching-Lin Chu),Dong-Yu Yang(Dong-Yu Yang),Wei Hung Chang(Wei Hung Chang),Po See Chen(Po See Chen),Yen 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.1
Objective: Hypoactivity in the reward system among patients with attention deficit hyperactivity disorder (ADHD) is a well-known phenomenon. Whether the activity in the reward pathway is related to harm avoidance, such as in sensitivity to punishment, is unclear. Evidence regarding the potential difference between ADHD patients and controls in terms of this association is scarce. Methods: Event-related functional magnetic resonance imaging was conducted on subjects performing the Iowa gambling test. Fourteen adults with ADHD and 14 controls were enrolled in the study. Results: Harm avoidance was found to be positively correlated with the activities of the bilateral orbitofrontal cortex and right insula in individuals with ADHD. A group difference was also confirmed. Conclusion: Understanding the roles of harm avoidance and brain activation during risk tasks is important.
Chi Zhang,Xiaolu Huang,Miao Yang,Si-Lu Chen,Jinhua Chen,Guilin Yang 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.3
A long-stroke nano-positioning stage driven by voice coil actuator (VCA) and supported by flexure guide is designed in this paper. The Halbach permanent magnet array is implemented in the VCA to improve the air-gap flux density with the magnetic concentration effect. The air-gap magnetic fi eld is modeled with an equivalent magnetic structure and verified by finite element analysis. The proposed equivalent magnetic structure reduces the number of boundary condition equations and hence simplifies the analysis procedure. Besides, a novel spring-damping tuning method is proposed based on the equivalent dynamic model of the closed-loop system. This tuning method regards P control and D control as a virtual spring and a virtual damper. The controller parameters are tuned in an intuitive way. Experimental results show that the positioning stage is capable of achieving a resolution of 40 nm within a stroke of 0.8 mm with high repeatability. The spring-damping tuning method ensures better control performance compared to Ziegler Nichols (Z–N) tuning method where overshoot and settling time are decreased.
Bidirectional Hybrid DWDM-PON for HDTV/Gigabit Ethernet/CATV Applications
Hai-Han Lu,Wen-Shing Tsai,Tzu-Shen Chien,Shih-Hung Chen,Yu-Chieh Chi,Che-Wei Liao 한국전자통신연구원 2007 ETRI Journal Vol.29 No.2
A new scheme for bi-directional HDTV/Gigabit Ethernet/CATV transmission over a hybrid densewavelength- division-multiplexing passive optical network (DWDM-PON) is proposed and demonstrated. It is based on injection-locked vertical-cavity surface-emitting lasers and distributed-feedback laser diodes as transmitters. Services with 129 HDTV channels, a 1.25 Gbps Gigabit Ethernet connection, and 77 CATV channels are successfully demonstrated over 40 km single-mode fiber links. Good performance of bit error rate, carrier-to-noise ratio, composite second order, and composite triple beat is achieved in our proposed bidirectional DWDM-PON.
Chiang, Chun-Chi,Lin, Jane-Ming,Chen, Wen-Lu,Tsai, Yi-Yu Masson Pub. USA 2007 Cornea Vol.26 No.7
PURPOSE:: To describe the use of allogeneic serum eye drops to treat 2 patients with chronic graft-versus-host disease (GVHD)-induced severe ocular surface disease. METHODS:: Small case series. RESULTS:: Conventional therapy failed to control the ocular symptoms of 2 patients with GVHD who presented with severe dry eye syndrome. Because autologous serum was unavailable in these cases, we used allogeneic serum eye drops as an alternate option for treating their ocular surface disease. Both donors had serologic tests performed before donation. Use of the allogeneic serum eye drops had a beneficial clinical effect, with marked attenuation of the patients’ symptoms. This therapy proved to be safe during 10 months of treatment. CONCLUSIONS:: Allogeneic serum eye drops may be a good alternative treatment for patients with severe dry eyes caused by GVHD.
Detecting small lung tumors in mouse models by refractive-index microradiology
Chien, Chia-Chi,Zhang, Guilin,Hwu, Y.,Liu, Ping,Yue, Weisheng,Sun, Jianqi,Li, Yan,Xue, Hongjie,Xu, Lisa X.,Wang, Chang Hai,Chen, Nanyow,Lu, Chien Hung,Lee, Ting-Kuo,Yang, Yuh-Cheng,Lu, Yen-Ta,Ching, Y Springer-Verlag 2011 ANALYTICAL AND BIOANALYTICAL CHEMISTRY Vol.401 No.3
Design of Current Sensorless Control for Totem-Pole Boost PFC Converter
Che-Yu Lu,Yi-Wen Hsu,Hung-Chi Chen 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
A simple current sensorless control for totem-pole boost converter is aimed to achieve superior power factor correction (PFC). In recent years, conduction loss and reverserecovery issues have been improved by the advanced power devices, and thus the converter’s efficiency and reliability are enhanced. Moreover, this converter topology has good potentiality for high-power applications. There are only two voltage sensors in both ac-side and dc-side for providing voltage information, which is an effective control strategy without current transducer. In addition, an equivalent singleswitch model of totem-pole boost PFC converter is offered that is an efficient approach to analyze the converter’s behaviors. Finally, some analytical results are given to evaluate the feasibility of the proposed current sensorless control method.