Security Analysis of the Khudra Lightweight Cryptosystem in the Vehicular Ad-hoc Networks

( Wei Li ),( Chenyu Ge ),( Dawu Gu ),( Linfeng Liao ),( Zhiyong Gao ),( Xiujin Shi ),( Ting Lu ),( Ya Liu ),( Zhiqiang Liu ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.7

With the enlargement of wireless technology, vehicular ad-hoc networks (VANETs) are rising as a hopeful way to realize smart cities and address a lot of vital transportation problems such as road security, convenience, and efficiency. To achieve data confidentiality, integrity and authentication applying lightweight cryptosystems is widely recognized as a rather efficient approach for the VANETs. The Khudra cipher is such a lightweight cryptosystem with a typical Generalized Feistel Network, and supports 80-bit secret key. Up to now, little research of fault analysis has been devoted to attacking Khudra. On the basis of the single nibble-oriented fault model, we propose a differential fault analysis on Khudra. The attack can recover its 80-bit secret key by introducing only 2 faults. The results in this study will provides vital references for the security evaluations of other lightweight ciphers in the VANETs.

Security Analysis of the Whirlpool Hash Function in the Cloud of Things

( Wei Li ),( Zhiyong Gao ),( Dawu Gu ),( Chenyu Ge ),( Linfeng Liao ),( Zhihong Zhou ),( Ya Liu ),( Zhiqiang Liu ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.1

With the advancement and deployment of leading-edge telecommunication technologies for sensing and collecting, computing related information, Cloud of Things (CoTs) has emerged as a typical application platform that is envisioned to revolutionize the daily activities of human society, such as intelligent transportation, modern logistics, food safety, environmental monitoring, etc. To avoid any possible malicious attack and resource abuse, employing hash functions is widely recognized as one of the most effective approaches for CoTs to achieve message integrity and data authentication. The Whirlpool hash function has served as part of the joint ISO/IEC 10118-3 International Standard by the International Organization for Standardization (ISO) and the International Electrotechnical Commission (IEC). In this paper, we propose an effective differential fault analysis on Whirlpool in the byte-oriented random fault model. The mathematical analysis and experimental results show that 8 random faults on average are required to obtain the current 512-bit message input of whirlpool and the secret key of HMAC-Whirlpool. Our work demonstrates that Whirlpool and HMAC-Whirlpool are both vulnerable to the single byte differential fault analysis. It provides a new reference for the security analysis of the same structure of the hash functions in the CoTs.

Security Analysis of the PHOTON Lightweight Cryptosystem in the Wireless Body Area Network

( Wei Li ),( Linfeng Liao ),( Dawu Gu ),( Chenyu Ge ),( Zhiyong Gao ),( Zhihong Zhou ),( Zheng Guo ),( Ya Liu ),( Zhiqiang Liu ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.1

With the advancement and deployment of wireless communication techniques, wireless body area network (WBAN) has emerged as a promising approach for e-healthcare that collects the data of vital body parameters and movements for sensing and communicating wearable or implantable healthful related information. In order to avoid any possible rancorous attacks and resource abuse, employing lightweight ciphers is most effective to implement encryption, decryption, message authentication and digital signature for security of WBAN. As a typical lightweight cryptosystem with an extended sponge function framework, the PHOTON family is flexible to provide security for the RFID and other highly-constrained devices. In this paper, we propose a differential fault analysis to break three flavors of the PHOTON family successfully. The mathematical analysis and simulating experimental results show that 33, 69 and 86 random faults in average are required to recover each message input for PHOTON-80 /20/16, PHOTON-160/36/36 and PHOTON-224/32/32, respectively. It is the first result of breaking PHOTON with the differential fault analysis. It provides a new reference for the security analysis of the same structure of the lightweight hash functions in the WBAN.

Injectable Hydrogels with Near-Infrared Controlled Drug Delivery for In Situ Photothermal/Endocrine Synergistic Endometriosis Therapy

Wei Tian,Chenyu Wang,Ran Chu,Haiyan Ge,Xiao Sun,Mingjiang Li 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Endometriosis is a common gynecological disease in women of childbearing age. Commonly used treatment methods, such as endocrine and surgical therapies, display poor therapeutic effects with a high relapse probability. Thus, novel treatments for endometriosis are required. Methods In our study, polydopamine (PDA), letrozole (LTZ), and agarose (AG) hydrogels were combined to construct an injectable hydrogel with near-infrared controlled drug delivery named LTZ-PDA@AG hydrogel for endometriosis treatment. The release of letrozole can be accurately controlled by the near-infrared light intensity, exposure duration, polydopamine concentration, and hydrogel composition. Meanwhile, we isolated endometrial stromal cells from endometrium in patients with endometriosis, and constructed the rats’ model of endometriosis to verify the biological effects of LTZ-PDA@AG hydrogel. Results Owing to the sufficiently deep penetration of near-infrared light, the LTZ-PDA@AG hydrogel displayed a high temperature increase for efficient photothermal therapy. In addition, high local temperatures can further enhance the diffusion and penetration of letrozole, thereby achieving excellent therapeutic effect in vivo. Importantly, the in vivo and vitro test demonstrated the capacity of the nanocomposite hydrogel for endocrine-photothermal synergistic therapy and the biocompatibility. Conclusion Our work proposes a novel concept for precision endometriosis therapy by photothermal-enhanced endocrine therapy for endometriosis, which is proposed for the first time for the treatment of endometriosis and demonstrates excellent potential for further clinical translation.

Simulation Research of Interference Magnetic Field Compensation Method on the Underwater Vehicle

Zhao Ta,Chenyu Wei,Zhouzhi Jian,Chengde Fu 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.4

It is one of the most difficult issues for underwater vehicle to accurately compensate the interference magnetic field elements in automatic navigation.The theory of geomagnetic navigation on underwater magnetic vehicle is complicated and the development of interference magnetic field compensation system is difficult, so in order to reserch the compensation method easily and effectively,it is a important way for using the finite element software on the computer to complete the modeling and simulation. In this paper, the space distribution characteristics of magnetic field around the vehicle are analyzed and the vector compensation mathematical model of interference magnetic field is established.At last, the feasibility of compensation method is testified by an united simulation system composed of Comsol Multiphysics and Matlab which is developed using the secondary development technology of software. The results show that the united simulation system can be convenient to complete the modeling and simulation of compensation method, not only accomplishing a magnetic field characteristic analysis and numerical calculation function, but also the simulation precision of compensation results is very high.

RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer

Liu Xiaoyi,Wei Qinglv,Yang Chenyue,Zhao Hongyan,Xu Jie,Mobet Youchaou,Luo Qingya,Yang Dan,Zuo Xinzhao,Chen Ningxuan,Yang Yu,Li Li,Wang Wei,Yu Jianhua,Xu Jing,Liu Tao,Yi Ping 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-

5-Methylcytosine (m5C) is a common RNA modification that modulates gene expression at the posttranscriptional level, but the crosstalk between m5C RNA modification and biomolecule condensation, as well as transcription factor-mediated transcriptional regulation, in ovarian cancer, is poorly understood. In this study, we revealed that the RNA methyltransferase NSUN2 facilitates mRNA m5C modification and forms a positive feedback regulatory loop with the transcription factor E2F1 in ovarian cancer. Specifically, NSUN2 promotes m5C modification of E2F1 mRNA and increases its stability, and E2F1 binds to the NSUN2 promoter, subsequently reciprocally activating NSUN2 transcription. The RNA binding protein YBX1 functions as the m5C reader and is involved in NSUN2-mediated E2F1 regulation. m5C modification promotes YBX1 phase separation, which upregulates E2F1 expression. In ovarian cancer, NSUN2 and YBX1 are amplified and upregulated, and higher expression of NSUN2 and YBX1 predicts a worse prognosis for ovarian cancer patients. Moreover, E2F1 transcriptionally regulates the expression of the oncogenes MYBL2 and RAD54L, driving ovarian cancer progression. Thus, our study delineates a NSUN2-E2F1-NSUN2 loop regulated by m5C modification in a manner dependent on YBX1 phase separation, and this previously unidentified pathway could be a promising target for ovarian cancer treatment.

Substrate Integrated Waveguide Power Divider Fed Dual-Dipole Array Antenna

Chen Yu,Wei Hong,Zhenqi Kuai 한국전자파학회JEES 2010 Journal of Electromagnetic Engineering and Science Vol.10 No.3

In the paper, a printed dual-dipole array antenna is presented. A 4-way planar SIW power divider is adopted for feeding the array antenna. The dual-dipole is adopted as radiation elements which greatly improves the impedance band. The measured bandwidth larger than 31 % for VSWR≤1.5 operating near 14 ㎓ is achieved and in agreement with the simulated results. The radiation E-plane and H-plane radiation pattern is presented in the paper. The radiation gain is also presented in the paper.