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        Detection of duck hepatitis virus serotype1 by biosensor based on imaging ellipsometry

        Chenghong Huang,Jixiang Li,Yu Tang,Yanyan Chen,Gang Jin 한국물리학회 2011 Current Applied Physics Vol.11 No.3

        A novel method for the detection of duck hepatitis virus serotype1 (DHV1) using a biosensor based on imaging ellipsometry (IE) is developed. Polyclonal antibodies against DHV1 were immobilized on silicon wafers through protein A and used to capture virus particles in sample. Signals on silicon surface were acquired directly in grayscale format on an imaging ellipsometry image. This study demonstrated that the assay is rapid and accurate for detection of duck hepatitis virus. Compared with traditional methods,this technique not only has high sensitivity as low as 8 × 10^-9.5 LD_50/ml, but can also simultaneously perform multiple serotype identification of DHV1, DHV1-g and DHV1-s. These results suggest that this biosensor might be a practicable diagnostic tool for duck hepatitis virus detection.

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        The Steady‑state Analysis of DC Distribution Network Embedded Droop Control and Power Flow Controller

        Da Xie,Luqing Zhang,Chenghong Gu,Yan Li 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.6

        Aiming at the DC distribution network based on the droop control, this paper proposes that the intersection of the internal characteristics of the node converter droop control and the external characteristics derived from the parameters of the DC distribution network is the actual node operation point. The quantitative relationship between the droop control characteristic parameters and the converter functions is discussed, and the comprehensive droop control characteristics of the multiconverter node is analyzed. The automatic adjustment method of droop control, containing the secondary adjustment and the third adjustment, is presented, and the power fow algorithm of DC distribution network, which considers the impact of power fow controller, droop control and automatic adjustment method, is derived. Finally, three cases about power fow controller, the secondary adjustment and the third adjustment are used to verify that droop control and its related regulation methods can optimize the operation conditions of DC distribution network.

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        FACILE SOLVOTHERMAL SYNTHESIS OF MESOSTRUCTURED CHITOSAN-COATED Fe 3 O 4 NANOPARTICLES AND ITS FURTHER MODIFICATION WITH FOLIC ACID FOR IMPROVING TARGETED DRUG DELIVERY

        MAO SHEN,CHENGLIN WU,WENPING JIA,CHENGHONG LI,ZHILI ZHANG,YANGMIN JIN,GUODONG FAN,CAIPING LIN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.7

        Mesostructured chitosan-coated Fe 3 O 4 nanoparticles (CS-coated Fe 3 O 4 NPs) were synthesizedby a facile one-step solvothermal method via using chitosan as a surface-modi¯cation agent. Subsequently, the surfaces of CS-coated Fe 3 O 4 NPs were successfully conjugated with folic acid(FA) molecules to obtain FA – CS-coated Fe 3 O 4 NPs for improving targeted drug delivery. Themorphology, chemical component and magnetic property of as-prepared composite nanoparticleswere characterized by Fourier transform infrared spectroscopy (FTIR), X-ray di®raction (XRD),dynamic light scattering (DLS), scanning transmission electron microscopy (SEM), transmissionelectron microscopy (TEM), thermal gravimetric analysis (TGA) and vibrating sample magne-tometer (VSM). Furthermore, doxorubicin hydrochloride (DOX) as a model drug was encap-sulated for investigating drug release pattern in vitro. The results show that the magnetizationsaturation value of FA – CS-coated Fe 3 O 4 NPs was about 28.5 emu/g, exhibiting super-paramagnetic properties and mesostructure. DOX could be loaded to FA – CS-coated Fe 3 O 4 NPswith high capacity about 27.9%, and the release rate of DOX could be adjusted by the pH value. This work demonstrates that the prepared magnetic nanoparticles have potential applications inthe treatment of cancer as targeting drug delivery carriers.

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