Comment on “Prognostic Role of Claudin-1 Immunohistochemistry in Malignant Solid Tumors: A Meta-Analysis”

Bolin Wang,Yan Huang 대한병리학회 2019 Journal of Pathology and Translational Medicine Vol.53 No.6

Identification and prevention of heterotopias in mouse neocortical neural cell migration incurred by surgical damages during utero electroporation procedures

Bolin Wang,Liting Ji,카우식 비샤이,Changyu Li,허성오 한국통합생물학회 2020 Animal cells and systems Vol.24 No.2

In utero electroporation (IUE) is a useful technique for gene delivery in embryonic mouse brain. IUE technique is used to investigate the mammalian brain development in vivo. However, according to recent studies, IUE methodology has some limitations like the formation of artificial ectopias and heterotopias at the micro-injection site. Thus far, the artificial heterotopias generated by physical trauma during IUE are rarely reported. Here, we reported the artificial heterotopias and ectopias generated from surgical damages of micropipette in detail, and moreover, we described the protocol to avoid these phenotypes. For the experimental purpose, we transferred empty plasmids (pCAGIG-GFP) with green fluorescent-labelled protein into the cortical cortex by IUE and then compared the structure of the cortex region between the injected and un-injected cerebral hemispheres. The coronary section showed that ectopias and heterotopias were appeared on imperfect-injected brains, and layer maker staining, which including Ctip2 and TBR1 and laminin, can differentiate the physical damage, revealing the neurons in artificial ectopic and heterotopic area were not properly arranged. Moreover, premature differentiation of neurons in ectopias and heterotopias were observed. To avoid heterotopias and ectopias, we carefully manipulated the method of IUE application. Thus, this study might be helpful for the in utero electroporator to distinguish the artificial ectopias and heterotopias that caused by the physical injury by microneedle and the ways to avoid those undesirable circumstances.

A Compare of Fuzzy Logic and Entropy Models : A Case Study of Assessment Analysis of Geohazard Susceptibility in Jianshi County of Qingjiang River Basin

Ningtao Wang,Tingting Shi,Ke Peng,Zhipeng Lian,Yiyong Li,Qing Wang,Wen Chen,Bolin Huang 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.4

Fuzzy logic model and entropy model are useful for the geohazard susceptibility zonation in Jianshi County of Qingjiang River Basin. In this paper, the same impact factors were chosen and the geohazard samples were considered in two cases with quantitative analysis method. The first case 162 geohazards chosen as samples and the other one all of 182 geohazards chose as samples. The authors completed the susceptibility zonation in the two different cases using the two models in order to analysis the effects of the two models. The results of the two models in different cases were almost the same in space, except small differences in some areas. The entropy model was more accurate for the analysis of relationship between impact factors and geohazards, but not stable for different geohazard samples. The fuzzy logic model was better for less geohazard samples. According to the analysis process, it was found that the fuzzy γ operation was the best which was defined in terms of the fuzzy algebraic product and the fuzzy algebraic sum. The results of fuzzy logic model were most useful when γ was 0.20. The fuzzy logic model and entropy model were useful for the geohazard susceptibility which was scientific and useful for the government to manage the geohazards and make the preliminary development plans.

Soil Layer Disturbance Caused by Pipe Jacking: Measurement and Simulation of a Case Study

Wenjie Ma,Binglong Wang,Xu Wang,Shunhua Zhou,Bolin Wang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.4

In this paper, areas of soil disturbed by pipe jack construction are categorized and analyzed in detail. Mechanisms of soil disturbance are discussed and patterns of soil deformation are studied using random medium theory. Lateral deformations in deep soil, pore water pressures, stratified settlement, and earth pressures are investigated using measurements from an electrical transmission pipeline project in China. The measurements show that soil layer movement can be predicted by monitoring changes in pore water pressure, and the amplitude of soil disturbance transverse to the pipeline is larger than that above the pipeline in this project. The distributions of stress components in the direction of, and vertical to, the pipeline axis are studied by numerical simulation. It shows that the closer to the pipeline axis, the greater the additional stress, the faster the attenuation speed, and the smaller the range of influence. Relationships of positive propulsion, friction, and stratum loss with longitudinal and transverse surface deformations are also discussed. The ground displacement is a coupling of the three factors to the action of the soil. The surface transverse subsidence with a main influence range of about ±4 D (D is outer diameter of pipe jacking). The findings from this study can be used as technical foundation and reference for the construction of similar projects.

Progress on fabrication and application of activated carbon sphere in recent decade

Jingming Lan,Baoying Wang,Chunmiao Bo,Bolin Gong,Junjie Ou 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.120 No.-

Activated carbon (AC) has a long history as an adsorbent material in many applications, including heavymetal and toxic gas removal as well as air and water filter applications. Activated carbon sphere (ACS) is aspecial type of activated carbon that has a high compressive strength and low ash content. Coal, asphalt,resins, polymers, lignin, carbohydrates, etc. can be utilized as precursors to prepare ACS using simple carbonizationand activation processes. Various parameters such as carbonization temperature, rising rate oftemperature, activation time, activation temperature, activator, different activation methods, etc. havesignificant effects on the performance and quality of the final product. As the size of ACS decreases, differentpreparation methods were adopted to prepare nano-sized or micron-sized spherical activated carbon. However, regardless of the size and shape of spherical activated carbon, it has a wide range of rolesfor the removal of heavy metals, organic dyes, carbon dioxide, volatile organic chemicals, catalyst carriers,gas and energy storage, chemical protection materials, and blood purification. This article mainlyreviews preparation methods of ACS over the last decade, and its applications and the challenges facedby ACS are discussed.

Construction of NH2-MIL-101(Fe) /TiO2 Heterojunction to Enhance the Charge Transfer in Photocatalytic Degradation of Antibiotics

Jiang Yuting,Key Laboratory of Science & Technology of Eco-Textile, Ministry of Edu,Zhang Hongyu,Wu Wei,Ji Bolin,Zhong Yi,Xu Hong,Feng Xueling,Wang Bijia,Ma Yimeng,Mao Zhiping,Zhang Linping 한국화학공학회 2024 Korean Journal of Chemical Engineering Vol.41 No.7

As an indispensable medicine, antibiotics are widely used in daily life, but following the substantial discharge of various wastewater, which result in antibiotic resistance of microbial pathogens and jeopardizes the health of ecosystems. There is an urgent need to tackle drug residues. After decades of intensive research, photocatalysis technology has been developed into an effi cient technology for wastewater treatment due to its economic and environmental-friendly properties. Here, the photocatalyst NH 2 -MIL-101(Fe)/TiO 2 composite was fabricated to degrade the antibiotics: tetracycline hydrochloride (TC), doxycycline hydrochloride (DC), and levofl oxacin hydrochloride (LEV). The NH 2 -MIL-101(Fe)/TiO 2 photocatalysts exhibited excellent visible light harvesting performance with a narrow band gap (2.19 eV), low recombination ratio of photoinduced carriers, good photoelectric response, low resistance and long charging life. NH 2 -MIL-101(Fe)/TiO 2 (MT0.50 molar ratio Fe:Ti = 1:1) showed the highest degradation eff ect, with the degradation rates of 91.52%, 80.11%, and 88.13% for TC, DC, and LEV in 6 h, with kinetic constants of 0.00510 min −1 , 0.00344 min −1 and 0.00503 min −1 , respectively. The catalysts exhibited signifi cantly increased photocatalytic activity and excellent stability compared to NH 2 -MIL-101 (Fe) and TiO 2 . In addition, MT0.50 still showed good photodegradation eff ect under simulated diff erent pH and ionic strength, indicating that MT0.50 has good adaptability and practical application. The study of photocatalytic mechanism showed that ·OH was the main active substance in the degradation process, which played an important role in degrading antibiotics. In addition, three possible degradation pathways for antibiotics were proposed based on the intermediates detected by LC–MS, and the photocatalysts also showed great stability and excellent antimicrobial eff ects. Therefore, the present study provides a new strategy and enriches the mechanisms involved in the wastewater treatment of NH 2 -MIL-101(Fe)/TiO 2 photodegradation of various antibiotics.