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      • KCI등재

        Disturbed homocysteine metabolism is associated with cancer

        Tauheed Hasan,Reetika Arora,Aniket Kumar Bansal,Reshmee Bhattacharya,Gurumayum Suraj Sharma,Laishram Rajendrakumar Singh 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

        Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in healthy individuals, while in hyperhomocysteinemic patients, it can be as high as 500 μmol/L. While increased homocysteine levels can cause symptoms such as osteoporosis and eye lens dislocation, high homocysteine levels are most closely associated with cardiovascular complications. Recent advances have shown that increased plasma Hcy is also a fundamental cause of neurodegenerative diseases (including Alzheimer’s disease, Parkinson’s disease, and dementia), diabetes, Down syndrome, and megaloblastic anemia, among others. In recent years, increased plasma homocysteine has also been shown to be closely related to cancer. In this review, we discuss the relation between elevated plasma Hcy levels and cancer, and we conclude that disturbed homocysteine metabolism is associated with cancer. Future clinical perspectives are also discussed.

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        Strength and permeation properties of alccofine activated low calcium fly ash geopolymer concrete

        Bharat Bhushan Jindal,Dhirendra Singhal,Sanjay Sharma,Aniket Yadav,Shubham Shekhar,Abhishek Anand 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.20 No.6

        This paper presents the experimental investigations on the compressive strength and permeation properties of geopolymer concrete prepared with low calcium fly ash as the primary binder activated with different percentage of Alccofine. The durability aspect was investigated by performing permeable voids and water absorption tests since permeability directly influences the durability properties. The test results show that Alccofine significantly improves the compressive strength and reduces the water permeability thus enhances the durability of geopolymer concrete at ambient curing regime which encourages the use of geopolymer concrete at ambient curing condition thus promising its use in general construction also.

      • FSIT : Fire Safety in Trains

        Amitoj Singh,Bakshish Singh,Bhupesh Grover,Gautam Bhutani,Aniket Sharma 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.6

        General incidents happening ongoing in trains nowadays happen due instant fire in railways because of multiple reasons resulting in health hazards and even deaths. This paper provides a remedy to reduce the losses of life occurring due to fire accidents in trains. In the past few years Indian railways has witnessed various forms of train accidents in which catching of fire is of serious concern. Fire on running bogie is severely dangerous than the stationary ones. The damage is severe because of lack of alertness and lack of communication which leads to the time delay in action. This project provides automation to the trains by applying automatic brakes and along with the ventilation in case of fire and smoke detection. The railway staff and passengers need to take all possible precautions in order to avoid any of the above mistakes so as to minimize the possibility of fire break out. The project consists of thermistor gas sensor, buzzer, fans, pneumatic actuators, solenoid pneumatic valve. Whenever the fire is detected with the help of fire sensors, thermistor and a safety circuit sends signal to solenoid valve and triggers the brakes and allows exhaust fans for proper air flow in and out of a chamber to avoid suffocation and it also starts the alarm to alert the authorities.

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