Determinants o f Disruptive Innovation That Influences F inancial S ervice Performance

Khalifa Khalfan Muftah Al Mansoori(Khalifa Khalfan Muftah Al Mansoori ),Mohammed Hariri Bakri(Mohammed Hariri Bakri ) People&Global Business Association 2023 Global Business and Finance Review Vol.28 No.2

Effect of sedative drug zolpidem tartrate on the development rate of Sarcophaga (Boettcherisca) peregrina (Diptera: Sarcophagidae)

Al‐Mekhlafi Fahd A.,Al‐Khalifa Mohammed S.,Wadaan Muhammad A. 한국곤충학회 2022 Entomological Research Vol.52 No.10

Applied entomotoxicology is the study of toxicants found in carrion insects and other matter, such as frass especially when body fluids or tissues cannot be used. The use of necropsy insects in medical and criminal investigations to detect toxicants has been done successfully. This study investigated the effect of the sedative drug zolpedim tartrate on the developmental rate and morphological parameters of the feeding and non-feeding stages of the carrion insect Sarcophaga peregrina Robineau-Desvoidy. Five cultures were prepared-one control and four cultures containing different concentrations of zolpidem tartrate (1, 2, 3, and 4 ppm). A total of 80 larvae were kept in each culture and provided with finely chopped liver containing the respective concentrations daily. The results obtained showed significant variations in the morphological parameters of the feeding and non-feeding stages, and negatively correlated with the concentrations compared with the control. The developmental time of the feeding and non-feeding stages positively correlated with the concentration of zolpidem tartrate. The results obtained indicate that zolpidem tartrate retards larval development and alters the estimation of the total developmental duration. When analyzing the entomological evidence of whether zolpidem tartrate may be responsible for death, it is important to consider its effects on PMI estimation.

Analysis of insects colonised on human corpses during autopsy in Riyadh, Saudi Arabia

Mashaly Ashraf,Al‐Khalifa Mohammed,Al‐Qahtni Abdulmani,Alshehri Adel 한국곤충학회 2020 Entomological Research Vol.50 No.7

In medicolegal cases, an analysis of the presence of insects on human bodies may have potential legal significance. This study investigates the presence of insects on human bodies during autopsies in legal medicine. It was implemented in Riyadh, Saudi Arabia. Nine cadavers were examined, respectively, from four cases of homicide, two cases of burning, one suicide, one accident and one case of neglect. Insects associated with the human corpses were carefully collected and identified using valid taxonomic keys. Three of the cadavers were of children with ages ranging from seven months to nine years. In seven cases decomposition had occurred outdoors while in two cases it was indoors. Overall, eleven different species of insects were identified. Six of the cases exhibited species from five families within Diptera (Calliphoridae, Muscidae, Ulidiidae, Tachinidae and Sarcophagidae), specifically Chrysomya albiceps (Wiedemann), Musca domestica (Linnaeus), Tachinidae sp. (Bigot), Physiphora alceae (Preyssler) and Sarcophaga dux (Thompson). Six of the cadavers hosted beetles, which were identified as Dermestes maculatus(DeGeer), D. frischii (Kugelann), Necrobia rufipes (Fabricius), Nitidula bipunctata (Linnaeus), Pimelia interjecta (Solier) and Latridiidae sp. (Erichson). Moreover, the suicide corpse was colonised by more fly species than the other corpses, while the beetles colonised the homicide and accident corpses more than the other corpses. Analysis of the diversity of insects on human corpses may lead to advances in the understanding of forensic entomology and more sophisticated estimates of the minimum post-mortem interval.

Chrysomya albiceps Wiedemann (Diptera: Calliphoridae) colonising poisoned rabbit carcasses

Mashaly Ashraf,Al‐Khalifa Mohammed,Al‐Qahtni Abdullah 한국곤충학회 2020 Entomological Research Vol.50 No.11

Chrysomia albiceps Wiedemann (Diptera: Calliphoridae) is one of the first insects to colonise human and animal carrion and thus one of the most important insects in forensic entomology. Since the presence of these blow flies have been reported in most of the provinces in Saudi Arabia, we analyse the succession patterns of C. albiceps on decomposing rabbit carcasses injected with heroin or administered orally with alcoholic beverages. Samples of flies from the carcasses of heroin or alcohol‐treated and untreated rabbits were obtained for 15 days post mortem. A total of 1,297 and 1,426 flies were attracted to rabbit carcasses during the heroin and alcohol tests, respectively. The blow flies appeared in different developmental instars (larvae, pupae and adults), and at all stages of decomposition. Administration of higher concentrations of heroin or higher amounts of alcohol were generally associated with an increase in the number of blow flies drawn to rabbit carcasses (P < 0.05). The highest number of blow flies were attracted during the decay stage of decomposition, and the lowest during the fresh stage. In the case of medicolegal investigation, when C. albiceps used as a forensic indicator, it is recommended that the impact of heroin or alcoholic beverages on the succession patterns be considered.

The effect of long-term supplementation with different dietary ω-6/ω-3 ratios on mineral content and ex vivo prostaglandin E2 release in bone of growing rabbits

Doha Mustafa Alnouri,Mohamed Fekry Serag El-Din,Abdulrhman Salih Al-Khalifa 한국영양학회 2014 Nutrition Research and Practice Vol.8 No.4

BACKGROUND/OBJECTIVES: The aim of this research was to study the different long term effects of consumption of dietary oil sources with varying omega-6/omega-3 (ω-6/ω-3) polyunsaturated fatty acids (PUFAs) ratios on bone marrow fatty acid level, ex vivo prostaglandin E₂ (PGE₂) release, and mineral content of bone in rabbits. MATERIALS/METHODS: For this purpose, weaning and female New Zealand white rabbits were purchased and randomly divided into five groups and offered ad libitum diets containing 70 g/kg of added oil for 100 days. The dietary lipid treatments were formulated to provide the following ratios of ω-6/ω-3 fatty acids: 8.68 soy bean oil (SBO control), 21.75 sesame oil (SO), 0.39 fish oil (FO), 0.63 algae oil (DHA), and 0.68 algae oils (DHA/ARA). DHA and ARA are two types of marine microalgae of the genus Crypthecodinium cohnii. RESULTS: The dietary treatments had significant effects on the bone marrow fatty acids of rabbits. Rabbits fed the FO diet, containing the highest ω-3 PUFA concentration, and those fed the SBO diet showed the highest ω-6 PUFA. On the other hand, a positive correlation was observed between Ex vivo PGE₂ level and the ω-6/ω-3 dietary ratio. Significant effects of dietary treatment on femur Ca, P, Mg, and Zn contents were observed in both genders. CONCLUSIONS: Findings of the current study clearly demonstrated that dietary PUFA, particularly ω-6/ω-3 and ARA/EPA ratios are important factors in determining bone marrow fatty acid profile, and this in turn determines the capacity of bone for synthesis of PGE₂, thereby reducing bone resorption and improving bone mass during growth.

Abdominoplasty Panniculus as a Source for Human Acellular Dermis: A Preliminary Report

Louri Nayef Abdulrahman,Dey Nigamananda,AlHasan Rashed N.,Abdulla Safa Hassan,Elsakka Mohamed,Gulreez Rasheeqa,Darwish Abdulla Hassan,Kadalmani Balamuthu,Al Khalifa Khalid Bin Ali 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.4

BACKGROUND: In extensive deep dermal burn injuries, split-thickness skin graft (STSG) has been the most preferred treatment option for resurfacing burn wounds. A thick split-thickness skin graft is ideal for preventing graft contracture but is associated with delayed donor healing and the lack of adequate donor skin. When applied with STSG, the dermal substitutes offer better-reconstructed skin than STSG alone. Human-derived acellular dermal matrix (HADM) obtained from cadaver skin is a dermal equivalent with good clinical outcomes. However, high cost and limited cadaver donor skin availability limit its clinical utility. Developing a low-cost preparation method and finding an alternate source of human donated skin can help reduce the cost. The objective of this study was to explore the feasibility of making HADM from abdominoplasty panniculus skin. METHODS: Skin samples were collected from the abdominoplasty panniculus of ten eligible donors with their informed consent. A combination of low-cost reagents-sodium chloride and hypotonic solution (water for injection) was used for decellularizing the skin. Characterization of the prepared Acellular Dermis Matrix prototype was done. RESULTS: The skin was deepidermized with one molar NaCl treatment at 37 ℃ for 24 h. The deepidermized dermis became acellular with hypotonic solution treatment at 4 ℃ for two weeks. The hematoxylin and eosin staining and cytotoxicity test confirmed the acellularity and non-cytotoxicity of the prepared HADM prototype. The HADM prototype also facilitated the formation of neo-epithelium in the 3D cell co-culture model. CONCLUSION: This study confirms that abdominoplasty panniculus can be a viable alternative for HADM preparation. Further characterization studies are required to prove the concept.