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BINARY STARS AND CLUSTERS AS TESTS OF STELLAR EVOLUTION MODELS
ANDERSEN J.,NORDSTROM B. The Korean Astronomical Society 1996 Journal of The Korean Astronomical Society Vol.29 No.suppl1
Precise masses, radii, and luminosities from eclipsing binaries and colour-magnitude diagrams for open clusters are classic tools in empirical tests of stellar evolution models. We review the accuracy and completeness required for such data to discriminate between current models and describe some recent. results with implications for convection theory.
EVOLUTION OF THE GALACTIC DISK: FOCUS ON THE SOLAR NEIGHBOURHOOD
ANDERSEN J.,NORDSTROM B.,OLSEN E. H.,MAYOR M.,PONT F. The Korean Astronomical Society 1996 Journal of The Korean Astronomical Society Vol.29 No.suppl1
The solar neighbourhood is the starting point for studies of the structure and evolution of the Galactic disk. Yet, our knowledge of the relative frequencies, distances, ages, chemical abundances, velocities, and birthplaces of the nearby stars is severely incomplete. We have determined complete, homogeneous, and precise such data for a kinematically unbiased sample of $\~$12,000 local F and G dwarf stars and describe a first, significant result from it.
Ethan J. Andersen,Madhav P. Nepal,Shaukat Ali 한국식물병리학회 2021 Plant Pathology Journal Vol.37 No.2
Tan spot of wheat, caused by Pyrenophora tritici-re- pentis (Ptr), results in a yield loss through chlorosis and necrosis of healthy leaf tissue. The major objective of this study was to compare gene expression in resistant and susceptible wheat cultivars after infection with Ptr ToxA-producing race 2 and direct infiltration with Ptr ToxA proteins. Greenhouse experiments included ex- posure of the wheat cultivars to pathogen inoculum or direct infiltration of leaf tissue with Ptr-ToxA protein isolate. Samples from the experiments were subjected to RNA sequencing. Results showed that ToxA RNA sequences were first detected in samples collected eight hours after treatments indicating that upon Ptr con- tact with wheat tissue, Ptr started expressing ToxA. The resistant wheat cultivar, in response to Ptr inocu- lum, expressed genes associated with plant resistance responses that were not expressed in the susceptible cultivar; genes of interest included five chitinases, eight transporters, five pathogen-detecting receptors, and multiple classes of signaling factors. Resistant and susceptible wheat cultivars therefore differed in their response in the expression of genes that encode chitin- ases, transporters, wall-associated kinases, permeases, and wound-induced proteins, among others. Plants exposed to Ptr inoculum expressed transcription fac- tors, kinases, receptors, and peroxidases, which are not expressed as highly in the control samples or samples infiltrated with ToxA. Several of the differentially ex- pressed genes between cultivars were found in the Ptr resistance QTLs on chromosomes 1A, 2D, 3B, and 5A. Future studies should elucidate the specific roles these genes play in the wheat response to Ptr.
Marquardt, J.U.,Seo, D.,Andersen, J.B.,Gillen, M.C.,Kim, M.S.,Conner, E.A.,Galle, P.R.,Factor, V.M.,Park, Y.N.,Thorgeirsson, S.S. Elsevier Science Publishers 2014 Journal of hepatology Vol.60 No.2
Background & Aims: Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC). However, the sequential molecular alterations driving malignant transformation of the pre-neoplastic lesions are not clearly defined. This lack of information represents a major challenge in the clinical management of patients at risk. Methods: We applied next-generation transcriptome sequencing to tumor-free surrounding liver (n=7), low- (n=4) and high-grade (n=9) dysplastic lesions, eHCC (n=5) and pHCC (n=3) from 8 HCC patients with hepatitis B infection. Integrative analyses of genetic and transcriptomic changes were performed to characterize the genomic alterations during hepatocarcinogenesis. Results: We report that changes in transcriptomes of early lesions including eHCC were modest and surprisingly homogenous. Extensive genetic alterations and subsequent activation of prognostic adverse signaling pathways occurred only late during hepatocarcinogenesis and were centered on TGFβ, WNT, NOTCH, and EMT-related genes highlighting the molecular diversity of pHCC. We further identify IGFALS as a key genetic determinant preferentially down-regulated in pHCC. Conclusions: Our results define new hallmarks in molecular stratification and therapy options for patients at risk for HCC, and merit larger prospective investigations to develop a modified clinical-decision making algorithm based on the individualized next-generation sequencing analyses.
STATCOM Helps to Guarantee a Stable System
Andersen, B.R,Gemmell, B.D.,Horwill, C.,Hanson, D.J. The Korean Institute of Power Electronics 2001 JOURNAL OF POWER ELECTRONICS Vol.1 No.2
Transmission System Operators are governed by operational security standards that are applied in real time. During system disturbances, the System Operators must rely on the installed protection and control equipment, prior to human intervention. New power electronic solutions bring rapid and repeatable responses to disturbances, which will help System Operators to guarantee a stable system. Last year, Alstom completed the world's first competitively bid STATCOM to support the voltage on National Grid's 400kV network that supplies London and the Southeast from the north of the UK. It is rated ${\pm}75MVAr$ and forms part of a Static Var System (SVS) with a total rating of 0 to 225MVAr. This paper will describe the reasons for its size, location, its chain-link configuration and give examples of its operating performance. The paper will also describe the features that allow this STATCOM to deliver much more than reactive compensation in support of a wider transmission service objective, as system conditions require.
Dan Andersen,sarah E. Pitts,Michael J. Silverman 한국음악치료학회 2012 한국음악치료학회지 Vol.14 No.1
The purpose of this pilot study was to evaluate the immediate effects of music therapy on fatigue in patients on a bone marrow transplant unit during a single-session randomized wait-list controlled trial utilizing an established psychometric instrument. Participants (N = 20) were randomly assigned to experimental or control groups. Participants in the experimental group received music therapy prior to completing the Lee Fatigue Scale (Lee, Hicks, & Nino-Murcia, 1991) while patients in the wait-list control condition received music therapy services after they completed the instrument. There was a significant between-group difference in the fatigue subscale, with experimental participants having less fatigue than control participants. Experimental participants tended to have slightly higher mean energy subscale scores than control participants. From the results of this study, it seems that music therapy can have an immediate impact on fatigue in patients undergoing bone marrow transplants. Limitations and suggestions for future research are provided.
Dan Andersen,Sarah E. Pitts,Michael J. Silverman 한국음악치료학회 2012 한국음악치료학회지 Vol.14 No.2
The purpose of this pilot study was to evaluate the immediate effects of music therapy on fatigue in patients on a bone marrow transplant unit during a single-session randomized wait-list controlled trial utilizing an established psychometric instrument. Participants (N = 20) were randomly assigned to experimental or control groups. Participants in the experimental group received music therapy prior to completing the Lee Fatigue Scale (Lee, Hicks, & Nino-Murcia, 1991) while patients in the wait-list control condition received music therapy services after they completed the instrument. There was a significant between-group difference in the fatigue subscale, with experimental participants having less fatigue than control participants. Experimental participants tended to have slightly higher mean energy subscale scores than control participants. From the results of this study, it seems that music therapy can have an immediate impact on fatigue in patients undergoing bone marrow transplants. Limitations and suggestions for future research are provided.
STATCOM Helps to Guarantee a Stable System
B.R.Andersen,B.D.Gemmell,C.Horwill,D.J.Hanson 전력전자학회 2001 ICPE(ISPE)논문집 Vol.2001 No.10
Transmission System Operators are governed by operational security standards that are applied in real time. During system disturbances, the System Operators must rely on the installed protection and control equipment, prior to human intervention. New power electronic solutions bring rapid and repeatable responses to disturbances, which will help System Operators to guarantee a stable system. Last year, ALSTOM completed the world's first competitively bid STATCOM to Support the voltage on National Grid's 400kV network that supplies London and the Southeast from the north of the UK. ft is rated ±75MVAr and forms part of a Static Var System (SVS) with a total rating of 0 to 225MVAr. This paper will describe the reasons for its size, location, its chain-link configuration and give examples of its operating performance. The paper will also describe the features that allow this STATCOM to deliver much more than reactive compensation in support of a wider transmission service objective, as system conditions require.<br/> Index Terms-AC System, Chain Circuit Convertor, FACTS, GTO, STATCOM, SVC, Voltage-Sourced Convenors.