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HVDC 케이블 접속재용 실리콘고무/나노 실리콘카바이드 콤포지트의 전기적 특성
허인회(Heo In HoI),홍영기(Young Gi-Hong),박재준(Jae-Jun Park) 대한전기학회 2021 전기학회논문지 Vol.70 No.4
In order to develop HVDC cable accessory, space charge exists at the interface between XLPE and EPDM composite or at the interface between XLPE and SiR. The larger the difference in ratio between the dielectric constant and the electrical conductivity of the two insulators, the greater the amount of space charge appears at the interface. The more and more space charges are stored at the interface, the higher the electric field distortion occurs. Therefore, in developing HVDC cable connection materials, Silicone rubber/nano silicon carbide (SiC) contents composites related to insulation and electrical conduction were manufactured. Nano SiC, a semiconducting inorganic material, has been modified to reinforce the interface of the composite mixed with silicon rubber.In addition, in order to study electrical ±HVDC dielectric breakdown characteristics and dielectric characteristics, modified ano SiC was filled with 0, 1, 3, 5, 7, 9wt%, dispersed, and nanocomposite was developed.
Heo In-Hoi(허인회),Im Chae-Woong(임채웅),Im Pil-Nam(임필남),Park Jae-Jun(박재준) 대한전기학회 2021 대한전기학회 학술대회 논문집 Vol.2021 No.10
High voltage-based heavy electric equipment (CT/PT, molded transformer, outdoor insulator, general bushing, recloser, etc.) Based on epoxy resin, two types of micro silica (W12EST, M10) are the most widely used fillers in the industrial field. A sample was prepared by filling contents 65wt% of W12est and M10 inorganic materials. There are three types of samples, and it was prepared through a drying process after moisture absorption and moisture absorption of three types of samples: epoxy resin, epoxy/surface-modified silica composite (W12est), and epoxy/surface-modified silica (M10). As the evaluation of the properties, the dielectric properties, mechanical tensile strength properties, and (±)HVDC dielectric breakdown properties, and the environmental resistance to outdoor insulation materials were evaluated for tracking and erosion properties.
생쥐 골수세포에서 아드리아마이신의 소핵생성에 미치는 N-마세틸시스테인의 억제효과
손수정(Su Jung Sohn),허인회(In Hoe Huh),최성규(Sung Gyu Choi),허문영(Moon Young Heo) 대한약학회 1993 약학회지 Vol.37 No.3
The anticlastogenic effect of N-acetylcysteine was tested in vivo in mouse bone-marrow micronucleus assay. The frequencies of micronuclei induced by adriamycin (5mg/kg i.p.) in bone marrow cells were decreased by the oral administration of N-acetylcysteine at 12 h before adriamycin injection. The observed suppressing effect was not a reflection of a delay in the formation of micronuclei by the cytotoxic effect of N-acetylcysteine. The anticlastogenic effects of SH compound including N-acetylcysteine, cysteine, cystine, S-carboxy methylcysteine and glutathione were also investigated by the multiple pretreatment. Each SH compound was administered orally every day for 5 days and adriamycin (5mg/kg i.p.) was injected at 24 h after the last dose of test compound. N-acetylcysteine and glutathione showed significantly the suppressive effect at dose of 10 and 25mg/kg for N-acetylcysteine and at the dose of 25mg/kg for glutathione. Our study suggests that N-acetylcysteine is capable of protecting the chromosomal damages in the normal cells during cancer chemotherapy by adriamycin, and may act as an anticlastogen against induction of micronuclei by superoxide generating agent such as adriamycin.
N-Methyl-N-Nitrosourea 유도 자매염색분체교환생성과 DNA메칠화에 대한 Galangin의 억제효과
손수정(Soo Jung Sohn),김정한(Jung Han Kim),김영진(Young Jin Kim),허인회(In Hoe Huh),허문영(Moon Young Heo) 대한약학회 1995 약학회지 Vol.39 No.1
In order to evaluate the suppressive effects of galangin on the DNA damage induced by N-methyl-N-nitrosourea(MNU), in vitro sister chromatid exchange(SCE) test using Chinese Hamster ovary(CHO) cells was performed. Also the determinations of [3H] MNU-induced total DNA binding and methylated DNA were performed to find out the mechanism of action by galangin. MNU-induced SCEs were significantly decreased by simultaneous and pretreatment of galangin when S-9 mix was added only. In post-treatment, however, the MNU-induced SCEs were not decreased whether S-9 mix was added or not. [3H] MNU-induced total DNA binding was significantly inhibited by the treatment of galangin in calf thymus DNA and CHO cells. HPLC analysis of DNA hydrolysates shows that galangin caused a dose-dependant decrease in calf thymus DNA, but not significant decrease in CHO cells. These results suggest that the inhibition of galangin on the MNU-induced SCEs is due to the decrease of DNA binding and methylation with MNU. Therefore, galangin may be useful as a chemopreventive agent of alkylating agents.