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Eicosanoids가 뇌허혈증 흰쥐의 에너지대사 및 Ca++ 이동에 미치는 영향
한현정(Hyun J. Han),이용규(Youg K. Lee),신정희(Jeung H. Shin),윤재순(Jae S. Yun) 대한약학회 1994 약학회지 Vol.38 No.1
We studied the effect of eicosanoids on the content of energy metabolites and the intrasynaptosomal Ca++([Ca++]i) concentration in cerebral ischemic rats. An ischemic model was made by bilateral carotid artery ligation (BCAL) and by incubation of synaptosomes under aglycemic and N2 gas bubbling condition. The content of ATP, creatine phosphate and glucose decreased at 15minutes after BCAL while that of lactate increased in male Wistar rats. Oral administration of EPA(100mg/ml/Kg/day) or DHA(16mg/ml/Kg/day) for 6 weeks improved both the decreases and the increase of the cerebral energy metabolites. In addition, the increase of [Ca++]i under BACL was suppressed by EPA or DHA treatment. When the both Wistar rats and SHR were administered orally with EPA or DHA for 6 weeks, the effect on the increase of [Ca++]i under ischemia by N2 gas bubbling were protected. From these results, it may be that EPA or DHA treatment were greatly contributed to preservation of ischemic cerebral energy metabolism and Ca++ concentration.
다중노즐 3D프린터의 모니터링 시스템을 활용한 사용자 맞춤형 근골격계 재활기기 소재에 관한 연구
이선우(S. W. Lee),한현정(H. J. Han),최민석(M. S. Choi),이선곤(S. K. Lee),김주형(J. H. Kim),김용래(Y. R. Kim),권장우(J. W. Kwon) 한국재활복지공학회 2018 한국재활복지공학회 학술대회논문집 Vol.2018 No.4
In this paper we implement a remote monitoring system to create customized musculoskeletal rehabilitation devices, introduce the structures and properties of 3D printer filament materials which have the flexible tactile sensor entered into the rehabilitation equipment material with multiple nozzle 3D printers In addition, the material with the properties of the filament flexible tactile sensor proposed in this paper is a brittle and elastic material, and its length is adjusted by using a micro-stage within the elastic range limits, and the resistance value is measured and analyzed. As a result, the resistance increased up to 190%. As the experiment repeated, the conductive filament did not win the tension and was cut off, resulting in infinite divergence and disconnection of the electrode.
Eicosanoids가 뇌허혈증 흰쥐의 에너지대사 및 Ca^++이동에 미치는 영향
한현정,이용규,신정희,윤재순 梨花女子大學校 藥學硏究所 1994 藥學硏究論文集 Vol.- No.4
We studied the effect of eicosanoids on the content of energy metabolites and the intrasynaptosomal Ca^++ (〔Ca^++〕_1) concentration in cerebral ischemic rats. An ischemic model was made by bilateral carotid artery ligation (BCAL) and by incubation of synaptosomes under aglycemic and N_2 gas bubbling condition. The content of ATP, creatine phosphate and glucose decreased at 15 minutes after BCAL while that of lactate increased in male Wistar rats. Oral administration of EPA(100 ㎎/㎖/㎏/day) or DHA(16 ㎎/㎖/㎏/day) for 6 weeks improved both the decreases and the increase of the cerebral energy metabolites. In addition, the increase of 〔Ca^++〕_1 under BACL was suppressed by EPA or DHA treatment. When the both Wistar rats and SHR were administered orally with EPA or DHA for 6 weeks, the effect on the increase of 〔Ca^++〕_1 under ischemia by N_2 gas bubbling were protected. From these results, it may be that EPA or DHA treatment were greatly contributed to preservation of ischemic cerebral energy metabolism and Ca^++ concentration.