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증례(症例) : 소장 폐쇄를 일으킨 장병 연관성 T-세포 림프종 1예
최인기 ( In Key Choi ),이일수 ( Il Soo Lee ),이중철 ( Jung Cheol Lee ),성백진 ( Back Jin Seong ),이정민 ( Jung Min Lee ),백지훈 ( Ji Hoon Back ),조용근 ( Yong Keun Cho ) 전북대학교 의과학연구소 2007 全北醫大論文集 Vol.31 No.1
Enteropathy-associated T-cell lymphoma (EATL) is an unusual malignancy presenting in patients with malabsorptive state. In Western countries, most patients with EATL have a short history of adult celiac sprue, later complicated by the onset of abdominal pain and weight loss, whereas a smaller proportion have a history of celiac sprue dating back to childhood. Presentation as an acute emergency with perforation, obstruction, or hemorrhage is common. The prognosis is poor. Both celiac sprue and EATL are very rare disease in Asia, except India and Middle East. Cases of EATL in Korea have been reported in only few cases. We report a 68-year-old male diagnosed as having EATL after segmental small bowel resection, who presented with intestinal obstruction.
증예(症例) : 류마티스 관절염 환자에서 Leflunomide와 Methotrexate의 병용 투여시 나타난 범혈구 감소증 1예
이일수 ( Il Soo Lee ),성백진 ( Back Jin Seong ),이중철 ( Jung Cheol Lee ),최인기 ( In Key Choi ),강혜미 ( Hye Mi Kang ),민병도 ( Byeng Do Min ),황민호 ( Min Ho Hwang ) 전북대학교 의과학연구소 2006 全北醫大論文集 Vol.30 No.2
DMARDs 단독투여에 반응하지 않는 류마티스 관절염 환자에서 Leflunomide와 MTX의 병용투여를 시도하게 되는 경우에 반드시 정기적인 혈액검사를 하고, 범형구 감소증 발생시 에는 약물 투여를 중단한 후 광범위 항생제, G-CSF를 사용하며, 병용투여 약물과 관련하여 folic acid 의 보충과 약물 배설을 유도하기 위해 charco1과 cholestyramine의 사용을 고려해야 할 것으로 사료된다. The combination therapy of leflunomide and methotrexate(MTX) for whom have inadequate response to long-term therapy of other disease modifying antirheumatic drug is increased recently in rheumatoid arthritis (RA). There are few reports that pancytopenia is more frequently occurred when treated with combination of leflunomide and MTX compared to single therapy. Even if some case be reporedt that the incidence and mortality of pancytopenia is increased after combination therapy, there are not sufficient case report of that. We report a case of pancytopenia due to combination therapy of leflunomide and MTX for 8months, which is improved by using folic acid, cholestyramine and granulocyte colony stimulating factor(G-CSF).
박정호 ( Jung Ho Park ),이태희 ( Tae Hee Lee ),천상렬 ( Sang Lyeol Cheon ),선제형 ( Jae Hyung Sun ),최인기 ( In Key Choi ),김용석 ( Yong Seok Kim ),최용우 ( Young Woo Choi ),강영우 ( Young Woo Kang ) 대한소화기학회 2009 대한소화기학회지 Vol.54 No.4
Anorexia nervosa, a syndrome most commonly affecting young women, is characterized by weight less than 85% of weight that is considered normal for that person`s age and height, distorted body image, and fear of becoming obese, and its mortality is up to 9%. We present a case of a 33-year-old woman with a 9-year history of anorexia nervosa. She admitted to our institution with decreased mentality, and her body mass index was 11.5 kg/m2 of the time admission. Initial aminotransferase level was severely elevated, but it was normalized solely with improved nutrition and weight gain. Five and sixteen days after the admission urinary tract infection and elevation of pancreatic enzymes occurred. They were successfully treated with antibiotics and nutritional support. Fifty seven days after the admission, she discharged. We report a case of acute hepatitis and pancreatitis treated with nutritional rehabilitation in a patient with severe anorexia nervosa for the first time in Korea. (Korean J Gastroenterol 2009;54:257-260)