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      • 갑상선 항진증에 관한 외과적 치료의 임상적 연구

        장일성,최길돈,하기정 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

        A clinical study of hyperthyroidism was performed for 20 patient who received operation at the department of surgery of C. N. U. H. from March, 1973 to July, 1987. The results were as follows: 1) In clinical classification, 14 cases (80%) were diffuse toxic goiter and 6 cases (20%) were nodular toxic goiter. 2) Male to female ratio was 1 : 19 and the highest incidence in the 3rd decade. 3) Main symptoms and signs were, in the order of decreasing frequency, neck mass (95%), palpitation (85%), fatigability (80%), heat intolerance (75%), weight loss (65%), tremor (60%) headache (50%). 4) Pulse rate changed from 130 per minute preoperatively to 60 postoperatively. 5) Thyroid function test revealed high level above the normal in 16 (80%) and the mean value of T_3RI_4 4.06mg/ml, T_3RI_4 10.48mg/ml, free T_4 4.65/ug/dl, postoperatively all cases showed teuthyroid function. 6) Electro-cardiographic findings were sinus tachycardia 9 cases (45%), normal 6 cases (30%). sinus bradycardia 5 cases (25%). 7) In preoperative preparation, Lugol solution was more frequently used 8 cases (40%) and others prophylthiouracil plus lugol solution 4 cases (20%), Inderal plus lugol solution 4 cases (20%) Methimazole plus lugol solution 2 cases (10%), prophylthiouracil plus Inderal plus comthyroid plus lugol solution 2 cases (10%). Average mean duration of preoperative preparation was 12.8 days. 8) The types of operation were in the order of decreasing frequency near total thyroidectomy 9 cases (45%), subtotal thyroidectomy 6 cases (30%), Lobectomy 4 cases (20%) and total thyroide ctomy 1 case (5%), 9) Early postoperative complication were transient tremor 3 cases (15%) transient hoarseness 1 case (5%), hypothyroidism 1 case (5%), recurrent hyperthyrodism 1 case (53%), hypoparathyroidism l. case (53%) but there was no case of operative motality.

      • 갑상선암의 임상적 고찰

        장일성,노승무,최길돈 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

        The thyroid cancer are more frequntly detected in anually due to improvement of diagnostic method and interesting knowledge of the cancer among the general population. This paper represent a clinical study of 80 cases of carcinoma of the thyroid gland which were histol ogically diagnosed and treated surgically at Chungnam National University Hospital from January 1981 to September 1988 with special emphasis on the surgical management of the thyroid cancer. The results were summerized as follows: 1) The incidence of the thyroid cancer was 22.22% among the 360 cases of the surgical thyroid disease and incidence of the thyroid cancer was increased anually. 2) The thyroid cancer was prevalent in third fourth decades of life (51.25% of all) and in female (5.67 to 1). 3) The average duration of the thyroid cancer was 2.9 years. 4) In histopathological classification of the thyroid cancer, papillary adenocarcinoma was 78.75% of all casses of thyroid cancer. 5) In the location of the thyroid cancer nodule,' 40/% of the thyroid cancer nodules were located in right lobe, 25% at the left lobe and the most prevalent location was right upper lobe(18.9O% of all). 6) In thyroid scanning of the thyroid cancer, the prevalent nodules were cold nodules, The most prevalent nodules were single cold nodules(62.50% of all). 7) In thyroid function test of the thyroid cancer, all most revealed normal function(88.75% of all). 8) Cervical lymphnode metastasis were present 29 casses (36.25%) and most common in papillary adenocarcinoma 26 cases(25%). Distant metastasis was present one case (1.25%), anaplastic cell carcinoma and the site was left breast. 9) The surgical procedure performed in thyroid cancer were followed unilateral lobectomy (28 cases), near total thyroidectomy (26 cases) and total thyroidectomy with neck dissection (1lcases) 10) The most common postoperative complication was transient hoarser ness in 14 casee (17.5O%). 11) After operation, the thyroid cancer recurrence rate was 8 cases (10% of all).

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