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지기환,이정,윤창호,하충건,Ji, Ki-Hwan,Lee, Jeong,Yun, Chang-Ho,Ha, Choong-Kun 대한임상독성학회 2006 대한임상독성학회지 Vol.4 No.2
Metronidazole is an antimicrobial drug widely used against various types of infectious agents, including protozoa, amoeba, Helicobacter pylori, and anaerobes. Metronidazole may produce some adverse effects on hematologic, immunologic, neurologic and other systems. We report a case of reversible metronidazole-induced encephalopathy. The toxic dose of metronidazole and the onset of encephalopathy were variable. Two patients showed abnormally high signal intensity in the bilateral dentate nucleus of cerebellum, and characteristic abnormalities were detected by brain magnetic resonance imaging (MRI) and T2-weighted images, fluid-attenuated inversion recovery images and/or diffusion weighted imaging (DWI). Discontinuation of metronidazole resulted in the improvement of the neurologic symptoms over a period of two to three weeks. We followed up the brain MRI with DWI in one case following obvious clinical improvement, and the previously detected lesion had disappeared.
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상시 계측결과를 이용한 고속철도 교량의 유지관리 기준치 설정
서형렬(Seo Hyeong Lyel),한상철(Han Sang Chul),지기환(Ji Ki Hwan) 한국철도학회 2006 한국철도학회 학술발표대회논문집 Vol.- No.-
Banwol bridge with steel plate girder and Pyongtaek bridge with PSC bos girder have been operated maintenance measuring system by the Seoul-Chonan of Kyongbu express railway. By analyzing the theoretical and experimental values of design load for these two bridge, the establishment of reference maintenance for measuring items was deduced from research. Two materials, steel and concrete plates, were considered as the upper structure. Actual measurement data for the behavior under speed, structural analysis results, and the presented references were analyzed and used to set up the reference establishment. The measuring items are stress(strain), displacement, dynamic acceleration, expansion movement, and dynamic frequency. The maintenance reference was established by comparing analytical and measuring values of the five items with respect to structural state class.
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