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최보영 ( Choi Bo Young ),조어린 ( Cho Eo Rin ),한민경 ( Han Min Kyung ),지선하 ( Jee Sun Ha ) 경희대학교 경영연구원 2017 의료경영학연구 Vol.11 No.1
Objectives: The conditions of peak bone mass and bone loss ratio before menopause are major risk factors of osteoporosis related fracture after menopause. Thus, bone health management is needed before bone loss aggressive menopause. Methods: This study analyzed association between bone mineral density(BMD) and general characteristics, nutritional intake and dietary habit, health condition and women health-related items in premenopausal women according to the data of Korean National Health and Nutritional Examination Survey(KNHANES V). Results: Prevalence rate of osteopenia was 34.3%. In the case of lumbar vertebra and femoral neck, there are 28.5% and 19.5% of prevalence rate of osteopenia respectively. And the osteopenia OR was on the increase in accordance with older age, lower weight and lower drinking frequency of carbonated beverage, coffee and alcohol, whereas the OR was on the decrease in the case of obesity. With regard to menarche age, as one year increased, the OR was increased accordingly. Conclusion: This study shows that the prevalence rate of osteopenia was high in normal premenopausal women. Thus, this study implies that normal premenopausal women have to take care of their bone health intently.
공복혈당 궤적에 따른 심장병 발생 위험: 국민건강보험공단 표본 코호트 연구
전주은 ( Jooeun Jeon ),조어린 ( Eo Rin Cho ),정금지 ( Keum Ji Jung ),지선하 ( Sun Ha Jee ) 한국보건정보통계학회 2016 보건정보통계학회지 Vol.41 No.4
Objectives: To classify trajectories of fasting blood glucose (FBS) levels and examine each trajectory`s associations with risk of cardiovascular disease (CVD). Methods: The National Health Insurance Service-National Sample Cohort (NHIS-NSC) sampled in the 2002 NHIS database was followed until 2010, and 13,829 participants aged 20 years and above had conducted nationwide health examinations annually. We used Cox proportional hazards models to examine the association of trajectories to risk of CVD. Four distinct trajectory groups were identified for FBS: low-stable, moderate-stable, elevated-upward, and High-upward. Results: During 88947.9 person-years of follow-up (mean follow-up, 6.4 years), we documented 2,778 incident case of CVD. Age-standardized incidence rate were increased with FBS levels (5,296.2 in low-stable group, 6,292.6 in moderate-stable group, and 8047.9 in elevated-upward group), but not in High-upward group. In multivariate models adjusted for age and sex, FBS was a significant predictor of CVD in elevated-upward group (hazard ratio (HR)=1.6, 95% confidence interval (CI):1.4-1.8) and High-upward group (HR=1.6, 95% CI:1.3-2.1). However, further adjustment for clinical covariates, only elevated-upward group was significantly associated with CVD (HR=1.2, 95% CI:1.1-1.4). Conclusions: Using the trajectory approach, we found that elevated-upward and High-upward FBS trajectories were associated with greater risk of CVD. These findings indicate the importance of FBS management across the lifespan, prognostic assessments and the targeting of prevention strategies to high-risk individuals.
프레밍험 모형은 한국인의 허혈성심질환 발생률을 과대 추정한다
안경아(Kyung A Ahn),윤지은(Ji Eun Yun),조어린(Eo Rin Cho),남정모(Chung Mo Nam),장양수(Yangsu Jang),지선하(Sun Ha Jee) 한국역학회 2006 Epidemiology and Health Vol.28 No.2
Background: The prediction of the absolute risk of ischemic heart disease (IHD) is commonly based on the risk prediction equations, originated from the Framingham Heart Study. Method: Framingham equation model was applied to participants from 2001 Korean National Health and Nutrition Examination Survey (KNHNES) to estimate the 5 year risk of IHD among Koreans ranging from 30 to 74 year-olds. The estimated risks were compared to the incidence and admission rates from two statistical reports among Koreans. Five year admission rate was estimated by the annual report from National Health Insurance Corporation (NHIC). Results: The average ages (standard deviation) were 34.31(27.23) year-old for KNHNES and 48.26(12.87) year-old for Framingham population used in this study. The risk of IHD predicted by the Framingham equation model substantially exceeded the risks actually reported in Korea. Five-year predicted risks by Framingham equation model were 4.86% for men and 1.93% for women; whereas from incidence data in Korea, five-year risks for acute myocardial infarction (AMI) were for 0.47% for men and 0.18% for women. These AMI incidence was similar to the admission rate (0.34 for men and 0.15 for women) estimated by NHIC. Also, 5-year admission rate of IHD were 1.16 for men and 0.78 for women. The magnitude of risk overestimation by Framingham mode is approximately at least 150 to 320%. Conclusion: Korean guidelines for the management for high risk group of IHD need to develop and correct for overestimation to avoid inflation of costs in primary prevention.