저체온 심폐우회로를 채용한 심장수술에서 요골 동맥압 파형분석을 이용한 심박출지수는 신뢰할 만한가?

정화성 ( Hwa Sung Jung ),김창원 ( Chang Won Kim ),김태엽 ( Tae Yop Kim ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.1

Background: Discrepancy of central-peripheral arterial pressure after cardiopulmonary bypass may affect the reliability of arterial pressure waveform derived cardiac index (APCI) monitoring. Methods: In 15 elective cardiac surgeries employing moderate hypothermic cardiopulmonary bypass (CPB), APCI from radial arterial cannula and pulmonary artery catheter derived cardiac index from thermodilution method (PACI) were measured. 1) after anesthesia induction (T1), 2) before CPB (T2), 3) immediately after CPB (T3) and 4) 1 hour after CPB (T4). APCI and PACI were analyzed by using the Bland-Altman analysis. Results: Biases of APCI and PACI at T1, T2, T3 and T4 were 0.093 L/min/m2, -0.053 L/min/m2, 0.485 L/min/m2 and -0.09 L/min/m2, respectively. The limits of agreement (2 SD) at T1, T2, T3 and T4 were from -2.285 to 2.471 L/min/m2, -2.475 to 2.369 L/min/m2, -2.255 to 3.225 L/min/m2 and -2.609 to 2.423 L/min/m2, respectively. Bias of APCI and PACI during entire period (T1-T4) was 0.095 L/min/m2 and 2 SD was from -2.387 to 2.557 L/min/m2. However, mean error % (2 SD/mean) of APCI at T1, T2, T3, and T4 were greater than 30%. Conclusions: Our results were not able to show that APCI measured from radial artery is comparable to PACI for hemodynamic monitoring during cardiac surgery employing moderate hypothermic CPB. Considering the limitations of PACI as a gold standard of hemodynamic monitoring in a certain clinical circumstance, further investigation employing other monitoring method than PACI may be followed to get more definitive conclusion. (Korean J Anesthesiol 2009; 57: 44~9)

비만중년여성의 댄스스포츠 프로그램이 체력, 피하지방두께 변화에 미치는 영향

정화성(Jung Hwa Sung) 한국유산소운동과학학회 2016 한국유산소운동과학회지 Vol.14 No.1

The purpose of this study was to analyze the effect of Dance sport SAMBA Program on health-related physical fitness and Skinfold thickness and Body girth in obese middle-aged women. SPSS 12.0 was used to calculate mean and SD, and ANCOVA was conducted to examine the group difference between paired sample t-test and pre-test and post-test. The level of significance was set at α=.05. 1. The change of health-related physical fitness was examined. In the EG, muscular strength(p<.01), muscle endurance(p<.05), flexibility(p<.01), and cardivascular endurance(p<.01). In the CG, there was no statistically significant difference in all factors. The change of body composition was examined. In the EG, there was statistically significant difference in weight(p<.001) and % body fat(p<.001), but no statistically significant difference was found in the CG. 2. The change of skinfold thickness was examined. In the EG, there was statistically significant difference in triceps, subscapular, midaxillary, suprailliac, and popliteal muscles(p<.001) and abdominal (p<.01), front thigh(p<.05), but there was no statistically significant difference in medial calf. In the CG, there was no statistically significant difference in all regions. In conclusion, as results of conducting the 12-week Dance sport SAMBA Program for obese middle- aged women, it was found that the program improved health-related and effectively reduced % body fat and skinfold thickness and Body girth. It is recommended that middle-aged women should do Dance sport SAMBA Program.

비만중년여성의 댄스스포츠 프로그램이 혈중지질 및 렙틴 변화에 미치는 영향

정화성(Jung Hwa Sung) 한국유산소운동과학학회 2015 한국유산소운동과학회지 Vol.13 No.1

This study conducted a 12-week dance sport program three times a week in middle-aged obese women in order to examine its effects on the change of body composition, blood lipid, leptin and provide the women with basic materials on an exercise prescription for their healthy and happy life. The difference before and after exercise was tested using paired-t test. AVCOVA was used to test the difference in modified mean value by group for the post-test under the control of pre-test. Finally the following results were obtained. 1. The change of blood lipid was found to have a statistically significant difference in total cholesterol and triglyceride(p<.001). There was a statistically significant difference in high density lipoprotein cholesterol(p<.01) and low density lipoprotein cholesterol(p<.05). 2. The change of leptin was found to have a statistically significant difference(p<.01). In conclusion, as a result of conducting the 12-week dance sport program in middle-aged obese women, effective increase and decrease were found in body composition, blood lipid, and letpin. It is considered that middle-aged obese women should participate in active programs such as dance sport program rather than excessive or boring exercises. It is recommended for more effective obesity management program that further study conducts a dance sport program and a dietary cure at the same time.

비만중년여성의 댄스스포츠 프로그램이 혈중지질 및 렙틴 변화에 미치는 영향

정화성 ( Jung Hwa-sung ) 대한체육학회 2015 대한스포츠융합학회지 (jcses) Vol.13 No.1

This study conducted a 12-week dance sport program three times a week in middle-aged obese women in order to examine its effects on the change of body composition, blood lipid, leptin and provide the women with basic materials on an exercise prescription for their healthy and happy life. The difference before and after exercise was tested using paired-t test. AVCOVA was used to test the difference in modified mean value by group for the post-test under the control of pre-test. Finally the following results were obtained. 1. The change of blood lipid was found to have a statistically significant difference in total cholesterol and triglyceride(p<.001). There was a statistically significant difference in high density lipoprotein cholesterol(p<.01) and low density lipoprotein cholesterol(p<.05). 2. The change of leptin was found to have a statistically significant difference(p<.01). In conclusion, as a result of conducting the 12-week dance sport program in middle-aged obese women, effective increase and decrease were found in body composition, blood lipid, and letpin. It is considered that middle-aged obese women should participate in active programs such as dance sport program rather than excessive or boring exercises. It is recommended for more effective obesity management program that further study conducts a dance sport program and a dietary cure at the same time.

비만중년여성의 댄스스포츠 프로그램이 체력, 피하지방두께 변화에 미치는 영향

정화성 ( Jung Hwa-sung ) 대한체육학회 2016 대한스포츠융합학회지 (jcses) Vol.14 No.1

The purpose of this study was to analyze the effect of Dance sport SAMBA Program on health-related physical fitness and Skinfold thickness and Body girth in obese middle-aged women. SPSS 12.0 was used to calculate mean and SD, and ANCOVA was conducted to examine the group difference between paired sample t-test and pre-test and post-test. The level of significance was set at α=.05. 1. The change of health-related physical fitness was examined. In the EG, muscular strength(p<.01), muscle endurance(p<.05), flexibility(p<.01), and cardivascular endurance(p<.01). In the CG, there was no statistically significant difference in all factors. The change of body composition was examined. In the EG, there was statistically significant difference in weight(p<.001) and % body fat(p<.001), but no statistically significant difference was found in the CG. 2. The change of skinfold thickness was examined. In the EG, there was statistically significant difference in triceps, subscapular, midaxillary, suprailliac, and popliteal muscles(p<.001) and abdominal (p<.01), front thigh(p<.05), but there was no statistically significant difference in medial calf. In the CG, there was no statistically significant difference in all regions. In conclusion, as results of conducting the 12-week Dance sport SAMBA Program for obese middleaged women, it was found that the program improved health-related and effectively reduced % body fat and skinfold thickness and Body girth. It is recommended that middle-aged women should do Dance sport SAMBA Program.

실험연구 : 흰쥐 횡격막 신경근 표본에서 Ondansetron과 Granisetron이 Rocuronium의 근 이완 작용에 미치는 효과

백종화 ( Chong Wha Baek ),강현 ( Hyun Kang ),정용훈 ( Yong Hun Jung ),박정원 ( Jung Won Park ),정화성 ( Hwa Sung Jung ),이윤경 ( Yoon Kyung Lee ),양홍석 ( Hong Seuk Yang ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.1

Background: Both ondansetron and granisetron exert their antiemetic effects via a blockade of the 5-hydroxytryptamine 3 receptor (5-HT3R). Because the 5-HT3R is a member of a superfamily of ligand-gated ion channels and has structural similarities to the nicotinic acetylcholine receptor (nAChR), a 5-HT3R antagonist may also inhibit the nAChR. This study examined the effects of 5-HT3R antagonists, ondansetron and granisetron, on rocuronium-induced neuromuscular blockade in vitro. Methods: Rat phrenic nerve-hemidiaphragm preparations were isolated and allocated randomly into seven groups (control, 1, 10, 100μg/ml of ondansetron, 0.1, 1, 10μg/ml of granisetron). Two studies were carried out using single twitch responses. In the cumulative dose-response study, rocuronium 1μg/ml and each doses of ondansetron or granisetron were administered simultaneously, and incremental 0.5μg/ml doses of rocuronium were added to obtain more than 95% neuromuscular twitch inhibition. ED5, ED50, ED90, and ED95 of rocuronium in each group were calculated using a logistic model. In the partial curarization study, the twitch heights were measured after administering ondansetron or granisetron (10 minutes after administering 3μg/ml rocuronium) and were measured 10 minutes later. The 2 twitch heights were then compared. Results: In the cumulative dose-response study, ondansetron 100μg/ml and granisetron 10μg/ml significantly reduced the ED50 of rocuronium (P < 0.05). There were no intergroup differences in the partial curarization study. Conclusions: High concentration of ondansetron and granisetron enhanced the neuromuscular blockade of rocuronium. Granisetron enhanced the neuromuscular blockade of rocuronium more potently than ondansetron. (Korean J Anesthesiol 2006; 51: 94~100)

요추 추간관절 활액낭의 경피적 치료 증례

이석진 ( Seuk Jin Lee ),김영기 ( Young Ki Kim ),정화성 ( Hwa Sung Jung ),임종범 ( Jong Bum Lim ),이청 ( Chung Lee ) 대한통증학회 2005 The Korean Journal of Pain Vol.18 No.2

증례보고 : Tay-Sachs Disease 환자의 전신마취 경험

김성수 ( Seong Su Kim ),조석주 ( Suk Ju Cho ),정화성 ( Hwa Sung Jung ) 대한마취과학회 2007 Korean Journal of Anesthesiology Vol.52 No.1

Tay-Sachs Disease (TSD), the most common form of GM2 gangliosidosis, is an autosomal recessive inborn lysosomal glycosphingolipid storage disease which is resulted from the mutations that affect the α-subunit locus on chromosome 15 and cause a severe deficiency of hexosaminidase A. It is characterized by normal motor development in the first few months of life, followed by progressive weakness and loss of motor skills beginning around 6 months of life. Neurodegeneration is relentless and manifested as relentless motor and mental deterioration, beginning with motor incoordination, mental obtundation leading to muscular flaccidity, blindness, and increasing dementia, with death occurring by the age of 4 or 5 years. We report a successful anesthetic management in a patient with Tay-Sachs Diseases for tracheostomy and feeding gastrostomy. (Korean J Anesthesiol 2007; 52: 107~10)

승모판막 성형수술에서 삼차원 경식도 심장초음파의 적용(증례보고)

김성협 ( Seong Hyop Kim ),윤태균 ( Tae Gyoon Yoon ),김태엽 ( Tae Yop Kim ),정화성 ( Hwa Sung Jung ),김준석 ( Jun Seok Kim ),지현근 ( Hyun Keun Chee ),송명근 ( Meong Gun Song ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.54 No.6

증례보고 : 전자간증과 갑상샘기능저하증을 가진 환자에서 응급제왕절개술 후 발생한 호흡부전

김성수 ( Seong Su Kim ),강명수 ( Myong Soo Kang ),정화성 ( Hwa Sung Jung ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.57 No.3

Anesthesia and surgery in a patients with undiagnosed or untreated hypothyroidism can carries the risk of potential complications such as prolonged unconsciousness, respiratory insufficiency, hypotension, hyponatremia, congestive heart failure, and even coma. A 33-year-old gravida was admitted at 36 weeks gestation with hypertension, proteinuria, generalized edema, and intrauterine fetal growth retardation. She had thyroidectomy for thyroid mass six years ago. Because of doubt of uterine abruption, emergency cesarean section was performed without result of thyroid function test. Preeclamsia and mild hypothyroidism show similar symptoms and it can make difficult to diagnose hypothyroidism. We experienced delayed recovery and respiratory insufficiency in a patient with preeclamsia and undetected hypothyroidism during emergence from general anesthesia. She was fully recovered after ventilatory care in intensive care unit. (Korean J Anesthesiol 2009;57:398∼402)