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이진원(C.W.Lee),장욱진(W.J.Jang),이장무(J.M.Lee),박영일(Y.I.Park) 한국자동차공학회 1998 한국자동차공학회 춘 추계 학술대회 논문집 Vol.1998 No.5_2
This paper reviews the time-domain model of Ishihara and transforms it in the frequency domain. The frequency domain model of torque converter can be widely used in designing and analyzing power-train vibration characteristrics. The torque converter on the experiment, has a cut-off frequency below 10Hz as predicted in the numerical calculation.
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Wook J. Jang(장욱진),Young S. Kim(김영숙),Yeong L. Ha(하영래),Cherl W. Park(박철우),Young K, Ha(하영권),Jeong O. Kim(김정옥) 한국생명과학회 2010 생명과학회지 Vol.20 No.5
표고버섯균사체 고체배양물 분말과 액체배양물 분말을 2:1 (w/w)로 혼합한 시료 (LED로 명명)가 CCl₄로 유발된 숫컷 쥐의 간독성을 보호하는 효과에 대해 연구하였다. Vehicle 처리군(0.2 ㎖ 증류수), Control 처리군(0.2 ㎖ 증류수), LED 처리군(LED 100, 200, 300, 400 ㎎/㎏ BW을 0.2 ㎖ 증류수에 각각 혼합), 그리고 Silymarin 처리군(200 ㎎/㎏을 0.2 ㎖ 증류수에 용해)의 각 처리군(군당 여섯 마리)에 매일 2주간 투여한 다음, Vehicle 처리군을 제외한 모든 군에 CCl₄ (CCl₄:corn oil, 1:1 v/v; 0.5 ㎖/㎏ BW)를 복부에 주사하였다. 하루가 지난 후에 생화학적 지표성분을 분석하기 위해 혈액과 간 시료를 채취하였다. 모든 LED 처리에 의해 간 SOD, catalase, 그리고 GSH peroxidase의 활성이 증가하였으며, TBARS, tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) 그리고 interleukin-6 (IL-6)가 감소하였다. 그 결과, 혈청중의 GOT, GPT, 그리고 LDH의 활성이 감소하였다. LED의 간 기능보호효과가 가장 효과적으로 나타난 처리농도는 200 ㎎/㎏ BW였다. 이러한 결과로 보아 LED는 CCl₄로 유발된 SD 쥐의 간 손상을 보호하며, 이는 LED의 항산화능과 cytokine의 감소에 의한 것이다. 따라서, LED는 사람의 간독성보호를 위해 효과적으로 사용할 수 있을 것으로 생각된다. The protective effects of a powder mixed with solid-cultured and liquid-cultured Lentinus edodes mycelia (2 : 1, w/w) (designate LED) with different doses of carbon tetrachloride (CCl₄) on induced hepatotoxicity in male Sprague-Dawley (SD) rats was investigated. The rats were divided into seven groups (6 rats/group) and the following substances were administered orally to each group: Vehicle (0.2 ㎖ distilled water), Control (0.2 ㎖ distilled water), LED (LED 100, 200, 300 and 400 ㎎/㎏ BW in 0.2 ㎖ distilled water), and Silymarin (200 ㎎/Kg BW in 0.2 ㎖ distilled water). After two weeks of daily administration, all groups except for the Vehiclegroup were subjected to abdominal injection with CCl₄ (CCl₄ : corn oil, 1 : 1 v/v; 0.5 ㎖/㎏ BW). One day later, blood and liver samples were collected to analyze biomarkers. All LED treatments elevated hepatic superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH peroxidase) activities, and reduced thiobarbituric reactive substances (TBARS), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6), resulting in the reduction of glutamate-oxalate transaminase (GOT), glutamate-pyruvate transaminase (GPT) and lactic acid dehydrogenase (LDH) activities in plasma. These results indicate that LED effectively protected SD rat hepatotoxicity induced by CCl₄ through its antioxidative activity and reduction of some cytokines. The highest efficacy was found in LED 200 ㎎/㎏ BW, showing potential as a useful material for protection from hepatotoxicity in humans.
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한기정,장욱진,최태열,김춘원 한양대학교 의과대학 1986 한양의대 학술지 Vol.6 No.2
Total 494 specimens obtained from uterine cervix were cultured at the Han Yang University Hospital from July, 1983 to July, 1985. Laboratory data were analyzed from the point of view of polymicrobial infection and the following results were obtained. 1. 309 specimens (60.5%) of the total 494 specimens reveals positive cultures. 80(25.9%) of them had multiple isolates from a single specimen (Polymicrobial infection) and 229 (74.1%) had single isolates (Single microbial infection). 2. The distribution of organisms in polymicrobial infection were gram-negative Bacilli 47.7%, gram-positive cocci 46.4%, candida 5.3%, and anaerobes 0.7%. 3. The frequently isolated oraanisms in polymicrobial infection were E.coli (29.8%), coagulase (-) staphylococcus (21.9%), Enterococcus (16.6%), Kelbsiella (10.6%), and candida (5.3%). 4. The combination of organism in polymicrobial infection were Gram positive cocci & Gram negative bacilli (48.7%), both Gram negative bacilli (20.0%), both Gram positive cocci (16.3%), candida & bacteria (13.7%) and anaerobes & GRam positive bacilli (1.3%).
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