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RISS 인기검색어
- 검색키워드
- 저자 : 임형택 ( Hyung Taeck Lim ) (검색결과 4 건)
- 무료
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임형택,박히준,장지련,최일환,이석찬,김대수,신희섭,임사비나,Lim, Hyung-Taeck,Park, Hi-Joon,Jang, Ji-Ryeon,Choi, Il-Hwan,Lee, Seok-Chan,Kim, Dae-Soo,Shin, Hee-Sup,Lim, Sa-Bi-Na 경락경혈학회 2004 대한침구의학회지 Vol.21 No.2
Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint $ST_{36}$ by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on $ST_{36}$ and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at $ST_{36}$ compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing as $ST_{36}$ compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
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임사비나 ( Sa Bi Na Lim ),임형택 ( Hyung Taeck Lim ),박히준 ( Hi Joon Park ),장지련 ( Ji Ryeon Jang ),최일환 ( Il Hwan Choi ),이석찬 ( Seok Chan Lee ),김대수 ( Dae Soo Kim ),신희섭 ( Hee Sup Shin ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2
Objective: Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST36 by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods: Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on ST36 and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results: The writhing reflex decrease significantly after acupuncturing at ST(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST(36) compared with control groups(p<0.05). Conclusion: This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
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한약처방 JSB가 구금스트레스로 우울증을 유발한 생쥐의 행동과 생체지표에 미치는 영향
신윤민 ( Younmin Shin ),임형택 ( Hyung Taeck Lim ),황은영 ( Eun-young Hwang ),김가나 ( Ka-na Kim ),이원길 ( Won Kil Lee ),김연경 ( Yeongyeong Kim ),장희진 ( Heejin Jang ),최정준 ( Jeong June Choi ) 대한한방신경정신과학회 2021 동의신경정신과학회지 Vol.32 No.1
Objectives: Depression is a mood disorder showing low energy, loss of interest, anhedonia, and anxiety. It affects a patients' daily life. This disease is considered a social problem because the patient may commit suicide in extreme cases. JSB is composed of 12 Korean medicinal herbs. It has been prescribed to patients with depression. The objective of this study is to investigate anti-depressive effects of JSB on restraint stress-induced depression in a mouse model. Methods: Depression was induced by restraint stress. Mice were orally administered JSB at 10, 20, or 40 mg/kg for 14 days. Forced swimming test (FST) and open field test (OFT) were performed. Brain-derived neurotrophic factor (BDNF) mRNA level was measured by real time-PCR. Plasma levels of corticosterone and serotonin were measured by ELISA. Blood levels of AST and ALS were measured using a biochemical analyzer. Results: JSB treatment significantly reduced the immobility time in FST. BDNF mRNA level was increased by JSB treatment in the hippocampi of mice. Although the expression of TNF-α was also increased by JSB, such increase was not statistically significant. The increase of corticosterone level in plasma induced by restraint stress was significantly down-regulated by JSB. JSB reduced blood level of AST, but not ALT. Conclusions: JSB has a potential to manage depression, setting a foundation for clinical application of Korean medicine with safety.
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임사비나,임형택,박히준,장지련,최일환,이석찬,김대수,신희섭 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-
Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST_(36) by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment an ST_(36) and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at ST_(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST_(36) compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
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