http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
소병재,진영화,이상직,배유찬,손현주,정동수,이재구,박양순,박성윤,이규현,원창만,강영배 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.2
This study was conducted to establish the eradication plan by using rabies bait vaccines in the Republic of Korea. For the safety and efficacy of the oral rabies vaccine(Oral SAG-1;Virbac, Raboral V-RG;Merial), five kinds of animals(raccoon dogs, badgers, cats, dogs and mice) were tested. Neutralization peroxidase linked assay(NPLA) was used in detecting neutralization antibodies against rabies virus. Wild and domestic animals which were orally administered one and two or ten doses had no adverse events due to vaccine and specific pathological lesions, respectively. Viral Neutralization antibodies(VNA) in raccoon dogs were first detected 2 weeks post-ingestion(oral administration). VNA could be detected 4 weeks post-ingestion(oral administration) in all raccoon dogs. We tried the field trial of oral rabies vaccine(Raboral V-RG;Merial) on five cities in Kyonggi and Kangwon Provinces, i.e., Paju city, Dhongducheon city, Youncheon-gun, Cholwon-gun, Hwacheon-gun, among rabies infected regions. Seventy-five percentage of the vaccine were ingested in case of Cholwon-gun region 30 days after applying bait vaccine. Average antibody forming rate in raccoon dogs captured in the applied five cities was 32%(10/31) during April to November 2001. Neutralizing antibodies against rabies virus could not be detected in raccoon dogs and cats captured in other regions during the same period. Also, Rabies cases in the applied area were decreased or were not reported during 4∼5 months after applying rabies bait vaccine.