사람 태아 골모 세포에 대한 냉동 동종골과 근골격이식재의 골형성 유도에 관한 효과

윤호상,피성희,윤형근,Yoon, Ho-Sang,Pi, Sung-Hee,Yun, Hyeong-Geun 대한치주과학회 2006 Journal of Periodontal & Implant Science Vol.36 No.2

The purpose of this study was to investigate the effects of ICB(Irradiated frozen allogenic bone, Rocky Mountain Tissue Bank, USA) and MTF(Decalcified freeze-dried bone allograft, Musculoskeletal Transplant Foundation, USA) on the cell proliferation and differentiation of human fetal osteoblasts. Human fetal osteoblasts (hFOB1) were cultured with $10\;ng/m{\ell}$of ICB and MTF. The negatvie control group was cultured with DMSO and positive control group was cultured with BMF ($2\;ng/m{\ell}$). MIT was performed to examine the viability of the cell, and alkaline phosphatase activity was analyzed to examine the mineralization. Calcium accumulation was also evaluated. ICB and MTF did not increase the rate of the cellular proliferation of hFOB1s while they enhanced ALP and calcium accumulation. The expression of osteocalcin (OC) and bone silaloprotein (BSP) increased in hFOB1 treated with ICB and MTF ($10\;ng/m{\ell}$). These results suggest that ICB and MTF stimulate osteoblastic activity of the hFOBl.

MR 댐퍼를 이용한 대형 버스 현가장치의 반능동 제어

윤호상(Hosang Yoon),문일동(Ildong Moon),김재원(Jaewon Kim),오재윤(Chaeyoun Oh),이형원(Hyungwon Lee) 한국생산제조학회 2012 한국생산제조학회지 Vol.21 No.4

In this work, the semi-active control of a large-sized bus suspension system with an MR damper was studied. An MR damper model that can aptly describe the hysteretic characteristics of an MR damper was adopted. Parameter values of the MR damper model were suitably modified by considering the maximum damping force of a passive damper used in the suspension system of a real large-sized bus. In addition, a fuzzy logic controller was developed for semi-active control of a suspension system with an MR damper. The vertical acceleration at the attachment point of the MR damper and the relative velocity between sprung and unsprung masses were used as input variables, while voltage was used as the output variable. Straight-ahead driving simulations were performed on a road with a random road profile and on a flat road with a bump. In straight-ahead driving simulations, the vertical acceleration and pitch angle were measured to compare the riding performance of a suspension system with a passive damper with that of a suspension with an MR damper. In addition, a single lane change simulation was performed. In the simulation, the lateral acceleration and roll angle were measured in order to compare the handling performance of a suspension system using a passive damper with that of a suspension system using an MR damper.

초임 학교장의 학교공동체 구성원 간 갈등 관리 리더십 실천 경험에 관한 내러티브 탐구

윤호상(Yoon, Ho-Sang),연지연(Yeon, Jiyeon) 한국성인교육학회 2021 Andragogy Today : International Journal of Adult & Vol.24 No.4

본 연구의 목적은 초․중등학교의 초임 학교장들이 학교에서 겪게 되는 학교공동체 구성원 간의 다양한 갈등을 어떻게 인식하고 관리하며 리더십을 발휘하는지에 관해 탐구하는 것이다. 연구 방법으로는 Clandinin과 Connelly(2000)의 내러티브 탐구방법을 적용하였으며, 초임 학교장 3명을 대상으로 심층 면담, 현장관찰, 전화 면담, 이메일, 학교 경영 자료 등을 통하여 자료를 수집하였다. 수집된 자료는 Bedford와 Landry(2010)가 제시한 내러티브 분석과정에 따라 연구 참여자의 경험을 하나의 이야기로 삼아 내러티브의 삼차원적 공간 안에서 심층적으로 분석하였다. 연구결과 학교급과 각자의 교육현장에서의 삶은 달랐지만 초임 학교장으로서 겪은 학교공동체 구성원 간 갈등에 대한 경험은 유의미한 특징을 가지고 있음을 알 수 있었다. 첫째, 연구 참여자들은 학교 조직 내 갈등을 위험으로 판단하지 않고 긍정적 측면으로 인식하고 있었다. 둘째, 연구참여자들은 리더십 실천을 통해 갈등 상황을 기회로 전환할 수 있었으며, 비록 초임 학교장이었지만 갈등 관리 리더십 실천에 큰 어려움이 없었다. 셋째, 연구참여자들은 갈등 관리 리더십 실천을 통해 반성과 성찰을 환류하면서 새로운 갈등 관리 리더십을 실천하였다. 이와 같은 결과를 통해 연구자는 학교 공동체 구성원 간의 갈등 주체가 다양해지고 있고 양상이 복잡해지고 있으므로 학교장의 갈등 관리 리더십 실천에서는 학교공동체 구성원 간 갈등간리에서는 학교 구성원들이 학교공동체라는 인식을 가지고 협력하는 것과 교사, 학부모가 서로의 관계를 존중하고 상호 협력하는 관계를 발전시켜나가는 노력이 중요함을 논의하였다. The purpose of this study was to explore how the newly appointed school principals in elementary and secondary schools perceive, manage, and exercise leadership in various conflicts among school community members. As a research method, the narrative inquiry method of Clandinin and Connelly (2000) was applied, and data were collected through in-depth interviews, field observations, telephone interviews, e-mails, and school management data for three first-time principals. The collected data were analyzed in depth within the three-dimensional space of the narrative, using the experiences of the research participants as a story according to the narrative analysis process suggested by Bedford and Landry (2010). The research conclusions were as follows First, the study participants did not judge conflict within the school organization as a risk, but perceived it as a positive aspect. Second, the study participants were able to turn conflict situations into opportunities through leadership practice, and although they were the first principals, there was no great difficulty in practicing conflict management leadership. Third, the study participants practiced new conflict management leadership while giving back reflection and reflection through conflict management leadership practice. Through these results, the researcher found that the subjects of conflicts among members of the school community are becoming more diverse and complex. Therefore, in the conflict management leadership practice of the principal, in the conflict between members of the school community, cooperating with the recognition that school members are a school community, teachers, The importance of parents efforts to respect each other s relationship and develop a mutually cooperative relationship was discussed.

휠체어트레드밀과 암에르고미터 프로토콜별 생리적 반응 비교

윤호상 ( Ho-sang Yoon ),최승권 ( Seoung-gweon ) 한국특수체육학회 2021 한국특수체육학회지 Vol.29 No.2

본 연구의 목적은 암에르고미터 프로토콜과 휠체어트레드밀 프로토콜을 비교 분석하여 가장 생리적 반응이 높은 프로토콜을 제시하는데 있다. 연구 대상자는 Y 대학교 휠체어농구부 남자 선수 10명으로 구성되었다. 선행 연구된 암에르고미터 프로토콜 2가지(35W, 12.5W), 휠체어트레드밀 프로토콜 2가지(C, WA)를 사용하여 최대운동부하검사를 무선 배정으로 실시하였고, 심폐기능(최고산소섭취량, 최고심박수, 최고 환기량), 운동지속시간, 무산소성역치 시점을 20초 구간으로 필터링하여 비교분석하였으며, 혈중젖산농도는 최대운동부하검사 직후, 회복기 2분, 4분, 6분을 비교 분석하였다. 4가지 프로토콜에 따른 심폐기능, 운동지속시간, 무산소성역치 시점 차이를 one-way RM(4) ANOVA로, 4가지 프로토콜별 혈중젖산농도와 측정시점에 따른 차이 분석을 two-way RM(4x4) ANOVA로 분석하였다. 분석된 자료를 통하여 얻어진 결과는 다음과 같다. 첫째, 운동단계별 속도(8km/h)는 고정하고 경사도(0.5%)가 일정하게 증가하는 휠체어트레드밀의 WA 프로토콜이 최고산소섭취량, 최고심박수, 최고환기량, 혈중젖산농도가 가장 높게 나타났다. 둘째, 휠체어트레드밀의 WA 프로토콜이 가장 빨리 무산소성역치 시점에 도달하였으나, 이후 운동단계별 규칙적인 저강도 운동부하(0.5% 경사도 증가)로 검사의 조기 종료 없이 효과적으로 최고산소섭취량과 운동 지속시간을 이끌어 낼 수 있었다. 셋째, 피험자의 트레이닝 정도 등에 따라 생리적 반응의 결과 값은 다소 차이가 나타났지만, 프로토콜별 특성에 따라 생리적 반응의 결과 값은 유사한 분포를 나타냈다. The purpose of this study was to present the maximal physiological responses protocol with a competitive analysis between the arm ergometer one and the wheelchair treadmill one. Ten male wheelchair basketball players from the Y university performed the examinations for this study. The maximal graded exercise testing were performed randomly using two arm ergometer protocols in a precedent study and two wheelchair treadmill protocols. The points of the cardio pulmonary function(maximal oxygen intake; maximal heart rate; and maximal breathing capacity); exercise duration; and anaerobic threshold were filtered every twenty second and analyzed competitively. Also, the blood lactate concentration were analyzed competitively at the points of the right after the maximal graded exercise testing; and an recovery time in two-minutes, four-minutes and six-minutes. The one-way RM ANOVA was used for the analysis of the cardio pulmonary exercise duration; and anaerobic threshold with four protocols, and the two-way(4x4) RM ANOVA was used for the analysis of the blood lactate concentration(p<.05). The results has been drawn out with the outcomes analyzed as follows: Firstly, the highest values in the maximal oxygen intake, maximal heart rate, maximal breathing capacity and blood lactate concentration came from the WA protocol of the wheelchair treadmill with a fixed speed on the stage of exercise(8km/h) and with a steady rate of increase in the inclination. Secondly, The WA protocol of the wheelchair treadmill reached at the anaerobic threshold point at the fastest, however, the regular low-intensity graded exercise tolerance(0.5% of increase in the inclination) on stage of exercise drew the maximal oxygen intake and exercise duration effectively without the early termination of the examinations. Lastly, the measured values in the physiological response were somewhat different from subject to subject depending on the individual training level, however, the distribution of the measured values by subject were similar depending on the characteristics of each protocol.

상용차 필드조건을 고려한 무인 내구 시험법 개발

윤호상(Hosang Yoon),김유겸(Yukyeom Kim),조병룡(Byoungyong Cho) 한국자동차공학회 2009 한국자동차공학회 학술대회 및 전시회 Vol.2009 No.11

It is important that the vehicle parts and system is evaluated by durability test method for fatigue life in order to secure a stability and a reliability of them. As design standard of most of the vehicle parts and system demand a long life, durability test is highly expensive and uneconomical because of taking a long time. Therefore, it is quite important of evaluating ALT(Accelerated Life Testing) in short time.

멀티 스레드 프로그램에서의 경쟁 상황 재현 방법

윤호상(Hosang Yoon),유민수(Minsoo Ryu) 한국통신학회 2018 한국통신학회 학술대회논문집 Vol.2018 No.1

사람 태아 골모 세포에 대한 냉동 동종골과 근골격이식재의 골형성 유도에 관한 효과

윤호상 ( Ho Sang Yoon ),신형식 ( Hyung Shik Shin ) 원광대학교 치의학연구소 2005 圓光齒醫學 Vol.14 No.1

무선 ATM환경에서의 효과적인 핸드오버를 위한 새로운 크로스오버 스위치 검색 기법

윤호상(Hosang Yun),윤현수(Hyunsoo Yoon) 한국정보과학회 1999 한국정보과학회 학술발표논문집 Vol.26 No.1A

Wireless ATM network의 handover에서 중요한 문제중의 하나가 이동한 switch로의 새로운 connection의 설정이다. 연결 지향적인(connection-oriented) ATM network에서는 새로운 connection의 설정에 많은 시간이 소요된다. Connection 설정시간이 길어지게 되면, hanover 시간이 길어지게 되고 이로 인한 QoS, cell lose, cell miss ordering등의 문제가 발생하게 된다. 본 논문에서는 효과적이고 빠른 handover를 수행하기 위한 방안 중에서 기존의 path를 재 사용하는 Incremental path re-establishment 기법의 핵심인 Crossover Switch 검색 기법을 제시한다. 본 연구에서 제안하는 Crossover Switch 검색 알고리즘은 Wireless ATM의 backbone network은 구성이 고정되어 있고 현재의 switch에서 핸드오버 가능한 스위치들을 미리 알 수 있으므로 이들에 대한 Crossover switch를 미리 계산하여 핸드오버가 발생할 때 CX를 찾지 않고 미리 계산한 CX를 사용하므로 핸드오버 시간을 줄이는 방안이다. 따라서 이와같은 CX list preparing 방법을 이용하면 CX discovery overhead를 줄여 효과적인 path rerouting이 가능하다.

통행시간 기반 혼합분포모형 분석을 통한 도시철도 승객의 급행 탑승 여부 추정 연구

장진원,윤호상,박동주,Jang, Jinwon,Yoon, Hosang,Park, Dongjoo 한국ITS학회 2021 한국ITS학회논문지 Vol.20 No.5

대부분의 도시철도 시스템은 승객의 탑승열차 및 탑승열차종을 정확히 알 수 없다. 다수의 선행연구에서는 교통카드데이터와 열차시각표를 매칭하여 탑승열차를 추정하였으나, 추정이 불가능한 승객 또한 다수 존재한다. 본 연구의 9호선 사례분석 결과 교통카드데이터-열차시각표 매칭만으로는 약 28% 승객의 탑승열차종을 추정할 수 없음을 확인할 수 있었다. 이에 교통카드데이터-열차시각표 매칭과 본 연구에서 정의한 통행시간 기반 혼합확률분포분석을 순차적으로 적용하여 급행운영 도시철도노선 승객의 탑승열차종을 추정하는 방법을 개발하였다. 분석 결과, 298개 OD pair에서 본 연구의 검증 기준을 만족하는 합리적인 급행이용/비이용 승객 분류기준점을 도출할 수 있었다. Identifying the exact train and the type of train boarded by passengers is practically cumbersome. Previous studies identified the trains boarded by each passenger by matching the Automated Fare Collection (AFC) data and the train schedule diagram. However, this approach has been shown to be inefficient as the exact train boarded by a considerable number of passengers cannot be accurately determined. In this study, we demonstrate that the AFC data - diagram matching technique could not estimate 28% of the train type selected by passengers using the Seoul Metro line no.9. To obtain more accurate results, this paper developed a two-step method for estimating the train type boarded by passengers by applying the AFC data - diagram matching method followed by a mixture distribution analysis. As a result of the analysis, we derived reasonable express train use/non-use passenger classification points based on 298 origin-destination pairs that satisfied the verification criteria of this study.

속단의 생리활성성분이 치은섬유아세포의 세포주기조절에 미치는 영향

유석주,장길용,윤호상,최호철,선기종,김현아,피성희,신형식,유형근,You, Suk-Joo,Jang, Kil-Young,Yoon, Ho-Sang,Choi, Ho-Chul,Sung, Ki-Jong,Kim, Hyun-A,Pi, Sung-Hee,Shin, Hyung-Shik,You, Hyung-Keun 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.1

The purpose of present study was to investigate the effects of physiologically active compound (SD62-122) from Phlomidis Radix on the cell cycle progression and its molecular mechanism in human gingival fibroblasts(HGFs). For this purpose, fibroblasts were isolated and cultured from excisioned gingiva during crown lengthening procedure in healthy adult. The following parameter were evaluated that there are cell number counting, MIT assay, cell cycle progression, western blot analysis. The cell number and MIT assay of primary cultured fibroblast was not increased at 2 days but significant increased compare to negative control at 3days(p<0.05). S phase was increased and G1 phase decreased in both $10^{-8}M$ and $10^{-9}M$ of SD62-122 in cell cycle analysis. The cell cycle regulation protein levels of Cyclin $D_1$, Cyclin E, cdk 2, cdk 4 and cdk 6 were increased compare to control in both $10^{-8}M$ and $10^{-9}M$ of SD62-122. The protein levels of p21 and p53 were decreased compare to control, but the level of pRb was not changed compare to control in $10^{-9}M$ of SD2-122. These results suggested that physiologically active compound (SD62-122) isolated from Phlomidis Radix increases the cell proliferation and cell cycle progression in HGFs, which is linked to increased cell cycle regulation protein levels of Cyclin $D_1$, Cyclin E, cdk 2, cdk 4 and cdk 6, and decreased the levels of p21, p53.