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      • KCI등재후보

        한국인 성인에서 내장지방량과 죽상경화증 위험인자 및 좌심실 비대와의 상관관계

        윤중원(Jung Won Yun),이원영(Won Young Lee),김지연(Ji Youn Kim),박현덕(Hyun Duk Park),임성호(Seong Ho Lim),정찬희(Chan Hee Jung),김영춘(Young Chun Kim),김선우(Sun Woo Kim) 대한내과학회 2002 대한내과학회지 Vol.63 No.2

        Background: Obesity is an independent risk factor for the development of coronary artery disease and associated with insulin resistance, hyperlipidemia and hypertension. In many studies, visceral adipose tissue is highly correlated with adverse coronary risk profile. Left ventricular (LV) hypertrophy also is an independent risk factor for cardiovascular mortality and morbidity. However, few data are available concerning the relations of LV hypertrophy to body fat composition, especially in Korean subjects. Therefore, this study was intended to evaluate the relation between body fat distribution and atherosclerotic risk factors including metabolic parameters and LV mass. Methods: Total 138 subjects who visited the healthy promotion center in Kangbuk Samsung hospital (97 men, 41 women) were to recruited to the study. Body fat distribution was assessed by Abdomial CT (computer tomography) and Bioelectrical impedance analysis (Body Composition Analyzer Inbody 2.0, Biospace, Seoul, Korea) Results: Visceral adipose tissue volume was higher in male subjects while subcutaneous adipose tissue volume and % body fat were higher in female subjects (p<0.05). Serum triglyceride and uric acid level were elevated in male subjects but HDL-cholesterol level was elevated in female subjects (p<0.05). Increasing age was correlated with waist-hip ratio, visceral adipose tissue volume, abdominal fat/total body fat ratio, LV mass (p<0.05). Visceral adipose tissue volume was positively correlated with body mass index, waist-hip ratio, blood pressure, total cholesterol, triglyceride, uric acid and negatively correlated with HDL-cholesterol (p<0.05). After adjustment for age and sex, this correlation was significantly remained. LV mass was positively correlated with body mass index, waist-hip ratio, visceral adipose tissue volume, abdominal fat/total body fat ratio (p<0.05). In the multiple regression analysis, the independent predictor for LV mass was visceral adipose tissue volume (β=0.252, p<0.05). Conclusion: Body fat distribution is associated with traditional cardiovascular risk factors. Especially, visceral adipose tissue is correlated with the components of metabolic syndrome and LV mass which is independent risk factor of cardiovascular morbidity and mortality. (Korean J Med 63:177-185, 2002)

      • SCIESCOPUSKCI등재

        위암 재발에 의한 속발성 식도이완불능증 1 예

        박인옥(In Ok Park),서정열(Jung Yul Suh),정수석(Su Suk Chung),임성호(Seong Ho Lim),이은정(Eun Jung Rhee),윤중원(Jung Won Youn),이호철(Ho Chul Lee),박승하(Seung Ha Park),김정욱(Jeong Wook Kim),조용균(Yong Kyun Cho),이준행(Jun Haeng Lee 대한소화기기능성질환·운동학회 2002 Journal of Neurogastroenterology and Motility (JNM Vol.8 No.1

        Achalasia can be provoked by organic causes, and it is called secondary achalasia. Sometimes it is very difficult to distingush secondary achalasia from primary achalasia. We report a case of secondary achalasia due to recurrence of stomach cancer. A 45-year-old man came to our hospital due to three months history of dysphagia and regurgitation. Barium esophagogram showed concentric narrowing at the distal esophagus and dilatation of proximal esophagus. The esophagogastroduodenoscopy showed stenosis of gastroesophageal junction and the endoscope could not pass through it, but there was no evidence of malignancy. Esophageal manometry showed aperistalsis, compatible with achalasia. Abdominal CT showed soft tissue density near the gastroesophageal junction. However it was not possible to differentiate whether it was due to adhesion or malignancy. For correct diagnosis and treatment, explorolaparotomy was performed and it was diagnosed as secondary achalasia due to recurrence of stomach cancer.(Korean Journal of Gastrointestinal Motility 2002;8:53-57)

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