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십이지장 궤양 출혈로 내원한 환자에서 진단된 C 단백 결핍증으로 인해 발생한 장간막 정맥 혈전증
우재곤 ( Jae Gon Woo ),이지은 ( Ji Eun Lee ),권오언 ( Oh Un Kwon ),정경원 ( Kyoung Won Jung ),정창욱 ( Chang Wook Jung ),조대현 ( Dae Hyeon Cho ),유길종 ( Kil Jong Yu ),심상군 ( Sang Goon Shim ) 대한소화기학회 2011 대한소화기학회지 Vol.57 No.1
Mesenteric venous thrombosis is a clinically very rare disease, and may cause bowel infarction and gangrene. Difficulty in the dignosis the disease due to its non-specific symptoms and low prevalence can cause a clinically fatal situation. Mesenteric venous thrombosis may be caused by both congenital and acquired factors, and protein C deficiency, which is a very rare genetic disorder, is one of many causes of mesenteric thrombosis. The authors experienced a case of mesenteric venous thrombosis caused by protein C deficiency in a patient with duodenal ulcer bleeding, so here we report a case together with literature review. (Korean J Gastroenterol 2011;57:34-37)
이식신에 국소성으로 발생한 침습성 아스페르길루스증 1예
권오언 ( O Wen Kwon ),우재곤 ( Jae Gon Woo ),이지은 ( Ji Eun Yi ),정경원 ( Gyung Won Jung ),조성 ( Sung Cho ),김성록 ( Sung Rok Kim ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.2
Though the development of immunosuppressive agents has increased the survival rate of transplanted kidneys, the opportunistic infection has increased in transplant recipients. Aspergillus may cause invasive aspergillosis via sino-pulmonary route in immunocompromized patients. We report a rare case of invasive aspergillosis of a transplanted kidney without having disseminated disease. A 41 year-old female, who underwent cadaveric renal transplantation 10 months ago, presented with diarrhea and anemia. Ultrasound examination and CT scan revealed an abscess lesion in the transplanted kidney. Surgical curettage and percutaneous drainage were performed. Because, microscopic examination demonstrated fungal hyphae consistent with Aspergillus species, antifungal agents were prescribed. Later, partial transplant nephrectomy and embolization of the remnant kidney were performed.
전격성 간부전의 경과를 보인 원발성 신 아밀로이드 증 1예
박건태 ( Geon Tae Park ),조성 ( Seong Cho ),김성록 ( Sung Rok Kim ),권오언 ( Oh Wen Kwon ),우재곤 ( Jae Gon Woo ),이지은 ( Ji Eun Yi ),정경원 ( Gyung Won Jung ) 대한신장학회 2009 Kidney Research and Clinical Practice Vol.28 No.5
We report the case of a patient with primary renal amyloidosis, who was progressed to fulminant hepatic failure. A 68-year-old man visited our hospital for evaluation of anorexia, weight loss and hepatomegaly. Laboratory examination revealed proteinuria and azotemia. He was confirmed to have primary amyloidosis by renal biopsy. His renal function progressed to deteriorate rapidly with marked deterioration of liver function with cholestasis. Peritoneal dialysis and steroid therapy were started for reduction of urine output and rapid progression of azotemia, and aggravation of liver function. Azotemia was improved after peritoneal dialysis but the liver function worsened leading to hepatic failure, causing death. If jaundice has progressed in any patients with primary amyloidosis, liver transplantation and stem cell transplantation should be considered for preparation of hepatic failure.
Propylthiouracil 복용 후 발생한 ANCA positive RPGN
정경원 ( Gyung Won Jung ),조성 ( Seong Cho ),김성록 ( Sung Rok Kim ),권오언 ( Oh Wen Kwon ),우재곤 ( Jae Gon Woo ),이지은 ( Ji Eun Yi ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.3
Anti neutrophil cytoplasmic antibody (ANCA)-positive vasculitis and crescentic glomerulonephritis has been rarely reported in patients suffering from Graves` disease and treated with Propylthiouracil. We experienced a case of ANCA-positive crescentic glomerulonephritis presenting good prognosis after discontinuing Propylthiouracil. A 40-year-old female visited due to the proteinuria and hematuria in urinalysis. She had been medicated Propylthiouracil for 3 years. Blood pressure was 100/60 mmHg. BUN and serum creatinine were 24.7 mg/dL, and 1.9 mg/dL, respectively. Urinalysis revealed protein 1481 mg/day, many RBC`s/HPF (dysmorphic 80%), Serological ANCA was positive, anti-myeloperoxidase (MPO) antibody 1,922 AAU/ mL (normal <150 AAU/mL). The histologic finding showed crescentic glomerulonephritis on light microscopy, but no immuno deposit on immunofluorescence and light microscopy. So we diagnosed ANCA positive pauci-immune glomerulonephritis. Propylthiouracil was discontinued and steroid, cyclophosphamide was medicated within about 1 month, but stopped due to cytopenia. Patient`s creatinine level was maintained 1.3 mg/dL and showed stable progress for about over 18 months. We report this case that showed good prognosis after discontinuation of Propylthiouracil.
증례 잉어 담즙 생식 후 병발된 무뇨성 급성신부전과 급성간염 및 횡문근융해증
강구현 ( Gu Hyun Kang ),박건태 ( Geon Tae Park ),송준휘 ( Jun Whee Song ),이지은 ( Ji En Lee ),우재곤 ( Jae Gon Woo ),조성 ( Sung Cho ),김성록 ( Sung Rok Kim ) 대한신장학회 2008 Kidney Research and Clinical Practice Vol.27 No.3
Gall bladder of a common carp is taken in some areas of Asia as a traditional medicine for improvement of their general health problems like hypertension, poor visual acuity, and impotence. Many cases have been reported on acute hepatitis, acute renal failure, gastrointestinal problems and neurological symptoms following ingestion of raw carp bile juice. We experienced a case of anuric ARF, acute hepatitis, and rhabdomyolysis that developed after indigestion of raw carp bile juice, not yet seen in previous studies. In this case, anuric state of patient was resolved after 4 days with continuous renal replacement therapy. Thus we report this case with review of literature.