DNA 양상에 따른 한우의 근친계수와 혈연계수의 추정에 관한 연구

여정수,김재우,이은준,박노형,이문연 ( J . S . Yeo,J . W . Kim,E . J . Lee,N . H . Park,M . Y . Lee ) 한국축산학회 1998 한국축산학회지 Vol.40 No.2

Estimation of inbreeding and relationship coefficients using DNA fingerprinting in the Korean Cattle, revealed that the inbreeding coefficient dependent on band frequency in Korean Cattle(0.100) was lower at least 10% compared to foreign cattle breeds [Holstein(0.338), Charolais(0.217), Aberdeen-Angus(0.283), and Simmental(0.160)). Band sharing value of relationship coefficient groups(0.5, 0.25, 0.125, 0.0625) in Korean Cattle were 0.704, 0.611, 0.463, and 0.296 respectively. Genetic similarity has increased in group of higher relationship coefficients. Relationship coefficient(Y) on genetic similarity(X) could be accurately estimated as linear regression of Y = 0.526X + 0.469. Furthermore, the results will be useful to estimate genetic parameters of animal population without pedigree.

초산시 체중이 주요경제 형질에 미치는 영향

여정수,오봉국 ( Jung Sou Yeo,Bong Kug Ohh ) 한국축산학회 1978 한국축산학회지 Vol.20 No.3

This experiment was conducted to investigate the optimum body size at 18 weeks of age which would relate to other economic characters in layer. Data of first egg day, egg production, egg weight, body weight, feed efficiency, and adult mortality were collected at Poultry Breeding Farm, College of Agriculture, Seoul National University from March 25, 1976 to 7une 2, 1977. The results obtained were as follows: 1. The first egg day was significantly correlated with body weight at sexual maturity. Heavy body weight groups showed relatively earlier in first egg days than low body weight groups. 2. Egg production didn`t show close relation to body weight but there was a tendency that the relatively lighter body weight groups laid more eggs than higher groups. In this strain, optimum body weight at sexual maturity for egg production seemed to range from 1,275g to 1,425g. 3. In egg weight of this strain there was evidently critical point between heavy and light group at 1,425g in body weight at sexual maturity. Egg production, growth rate and sexual maturity were suggested as a second factors to influence egg weight. 4. Body weight at 18 weeks of age was highly correlated with body weight during laying period. 5. Feed requirement per ㎏ eggs produced showed highly positive correlation with initial body weight. Birds weighing from 1,275g to 1,325g at sexual maturity seemed to bring the best feed efficiency. 6. During laying period viability of the lightest group weighing below 1,275g at 18 weeks of age was observed relatively low, but geneal tendency between body weight and viability was throught to be flexible.

Probe 종류에 따른 축우의 DNA 지문의 양상

여정수,이은준 ( J . S . Yeo,E . J . Lee ) 한국축산학회 1996 한국축산학회지 Vol.38 No.2

더미 다중인자 차원축소법에 의한 검증력과 주요 유전자 규명

여정수,라부미,이호근,이성원,이제영,Yeo, Jungsou,La, Boomi,Lee, Ho-Guen,Lee, Seong-Won,Lee, Jea-Young 한국데이터정보과학회 2013 한국데이터정보과학회지 Vol.24 No.2

광범위 유전자 관련 연구에서는 유전자-유전자 상호작용을 규명하는 것은 매우 중요하다. 최근 유전자-유전자 상호작용을 규명하는데에 대한 많은 연구가 진행되고 있다. 그 중 하나로 더미 다중인자 차원축소법이다. 이 연구의 목적은 모의실험을 통해 유전자-유전자 상호작용 파악하기 위한 더미 다중인자 차원축소의 검증력을 평가하는 것이다. 또한 이 방법을 적용하여 한우모집단에서 경제형질을 위한 단일 염기 다형성의 상호작용 효과를 확인하였다. It is important to detect the gene-gene interaction in GWAS (genome-wide association study). There have been many studies on detecting gene-gene interaction. The one is D-MDR (dummy multifoactor dimensionality reduction) method. The goal of this study is to evaluate the power of D-MDR for identifying gene-gene interaction by simulation. Also we applied the method on the identify interaction effects of single nucleotide polymorphisms (SNPs) responsible for economic traits in a Korean cattle population (real data).

난용계의 주요경제형질에 대한 상가적 ( 相加的 ) 및 모체유전효과의 상관계수 추정

여정수,오봉국 ( Jung Sou Yeo,Bong Kug Ohh ) 한국축산학회 1983 한국축산학회지 Vol.25 No.4

Data from the 2718 birds of two Leghorn populations for three generations were analyzed to determine the genetic correlations between direct effects(γXoYo), maternal genetic effects (γXmYm) and direct-maternal genetic effects (γXoYm, γXmYo) for X and Y traits. It was found that in A line egg production will be improved according to light initial body weight, increase of egg weight highly correlated with body weight will be higher than the expected estimates on the basis of γXoYo, and egg production improvement after 43 weeks of age will derive the decrease of egg weight in the causes of negative γXmYo between egg number and egg weight. In D line, highly negative coefficient in yXmYo between body weight and egg number, body weight and egg weight, and egg number and egg weight will provide increase of egg number from lighten body weight, while correlated response between egg weight and body weight will be biased below the expected estimates and also decrease of egg weight dependent on increased egg number will be less than the expected estimates.

난용계 모체유전효과를 이용한 유전변이 추정에 관한 연구

여정수,오봉국 ( J . S . Yeo,B . K . Ohh ) 한국축산학회 1982 한국축산학회지 Vol.24 No.1

Data from the 1,131 birds of synthetic population (A) and 1,587 birds of selected population (D) for three generations were analyzed to determine the different components; additive variance, maternal genetic variance and covariance between additive-maternal genetic effects of economic traits. Coefficients of variations of mean performances in synthetic line were decreased and those of selected line were nearly constant year by year. It was found that maternal genetic variances were important in all traits except egg weights before 43 weeks of age in both lines, showing greater values in synthetic line than in selected line. Correlations with additive-maternal genetic variances, when present, were highly negative in all traits which seemed to influence to derive difference between heritabilities from sire and dam variance components through sib analysis in the absence of dominant effect. Adjusted heritabilities included additive variance, maternal genetic variance and covariance between additive-maternal genetic effects were large in body weights at different age and small in egg numbers and initial egg weights of both lines.

한국 재래축종인 (在來畜種) 한우의 염색체 분석

여정수 ( Jung Sou Yeo ) 한국축산학회 1984 한국축산학회지 Vol.26 No.3

For the purpose of the distinguishing the sophisticated chromosome spread procedure and chromosome banding pattern of the Korean Native Cattle, fifty heads were examined cytogenetically using the bone marrow culture technique. Red bone marrow from femur and sternum was mixed with one drop of 1% colchicine in 20 gage needle and 7-10 cc media, and then cultured for 2-3 hours at 37.5C. After hypotonic treatment by 1% sodium citrate for 30 minutes at 37.5C, it was fixed in 3:1 methanol acetic acid. The slides chromosome were prepared and air- dried. Metaphase plate of chromosome was found at slide treated by the Giemsa staining. Chromosome number of the Korean Native Cattle was 60 at haploid, as telocentric autosome and sex chromosome X and Y were sub-metacentric. To be clearly identify the homology chromosome and banding pattern in each chromosome complement, prepared chromosome slides were treated with 0.03-0.04% trypsin solution (with Hank`s BSS free Ca and Mg) at 25℃ for 10 minutes, and then rinsed 70% and 100% ethanol. In comparison standardised banding pattern of the Korean Native Cattle with the other cattle breeds, it was found that 7 pairs of autosome in the Korean Native Cattle; 6, 7, 16 19, 24, 25 and 27 were not matched with other domestic cattle.

G - , C - banding 에 의한 닭의 염색체 분석

여정수 ( Jung Sou Yeo ) 한국축산학회 1985 한국축산학회지 Vol.27 No.12

Precise analysis of chromosomal genetic materials is not only important at cytogenetics field but basic steps of molecular genetics. To approach these aims through this study, G- and C- banding techniques were used. G- banding was found more accurate patterns at macro-chromosomes compared with recent reported banding patterns. While C- banding was gotten precise heterochromatin site of all chromosomes. So genetic markers dependent on economic traits of chicken will be identified based on advanced banding techniques.

DNA 지문을 이용한 한국 토종닭의 유전적 소질에 관한 연구

여정수(J . S . Yeo),김재우(J . W . Kim) 한국축산학회 1995 한국축산학회지 Vol.37 No.4

In order to identify the genetic compositions of the grey brown Korean Native Chicken(gKNC), this study was compared to other 6 strains of birds by DN.A fingerprintings. The gKNC was nearly fixed as genetic strain in homozygotic ratio and band sharing within grain of DNA bands. Band sharing of inter-strain of the gKNC with yellow brown Native Chicken was showed high similarity(0.76), and considerable band sharing of 0.325 with commercial broiler was suggested possibility of improvement as meat type. Through pedigree analysis of DNA bands, paternal DNA bands of gKNC were inherited significantly higher than maternal to progeny. Strain specific band, genetic composition of meat type, and powerful inheritance of sire would be important tools to improve the grey brown Korean Native Chicken in a future.

한국 재래돼지의 유전물질 분석에 관한 연구

여정수(J . S . Yeo),정경진(K . J . Chung) 한국축산학회 1991 한국축산학회지 Vol.33 No.8

An experiment was carried out to identify the chromosomal characteristics of the Korean Native Pig by comparing its morphological features with those of the Landrace breed. The results obtained from this study are as follows ; l. The Korean Native Pig had 38 chromosomes composed of 36 automosomes and 2 sex chromosomes. The length of p-arm in #2, 7, 8, 9, 11, 12, X and Y chromosomes of the Korean Native Pig was significantly shorter than those of Landrace breed. 2. The G-banding pattern in #l, 9 and X of the Korean Native Pig had distinctive bands which were different from those of Landrace breed. The #11 of the Korean Native Pig had a distinctive dark C-band at centromere while that of Landrace has a light hand. The #15 chromosome of Landrace breed had a more broad and distinctive band than that of the Korean Native Pig.