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102명의 비흑색종 피부암 환자에 대한 Mohs 미세도식수술 치료 경험
양보희 ( Bo Hee Yang ),변지원 ( Ji Won Byun ),이승규 ( Seung Gyu Lee ),인승균 ( Seung Gyun In ),이현숙 ( Hyeon Sook Lee ),정기양 ( Kee Yang Chung ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ),송희진 ( Hee Jin Song ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.11
Background: Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery, which offers superior cure rates to other options in the treatment of non-melanoma skin cancers. Objective: The aim of this study is to investigate the clinical characteristics and recurrence rate of the non-melanoma skin cancer and to estimate the safeties of MMS. Methods: We retrospectively evaluated 102 patients who had been diagnosed with non-melanoma skin cancer and treated by MMS from May 2008 to September 2011. Results: The most common cancer was basal cell carcinoma (63.72%), followed by squamous cell carcinoma (31.38%). The local flap was the most common method to repair surgical defects (74.5%), followed by primary closure (17.64%). Cervical lymph node metastasis was confirmed in 1 case (0.98%). Recurrence after MMS was observed in 1 of 102 patients (0.98%). Conclusion: MMS is a safe method for the treatment of non-melanoma skin cancer. (Korean J Dermatol 2012;50(11):931∼936)
경구 Isotretinoin으로 빠른 호전을 보인 염증성표재성파종성한공각화증
양보희 ( Bo Hee Yang ),방찬일 ( Chan Yl Bang ),변지원 ( Ji Won Byun ),한성협 ( Sung Hyub Han ),송희진 ( Hee Jin Song ),인승균 ( Seung Gyun In ),최광성 ( Gwang Seong Choi ),신정현 ( Jeong Hyun Shin ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7
Disseminated superficial porokeratosis is a keratinization disorder characterized by multiple brown, atrophic patches with sharply demarcated and hypertrophic ridges. Atypical cases of disseminated superficial porokeratosis with acute exacerbation accompanied by severe pruritus have been reported as eruptive pruritic papular porokeratosis or inflammatory disseminated superficial porokeratosis. We report a case of inflammatory disseminated superficial porokeratosis in a 53-year-old man who was successfully treated with oral isotretinoin.
양보희 ( Bo Hee Yang ),방찬일 ( Chan Yl Bang ),변지원 ( Ji Won Byun ),한성협 ( Sung Hyub Han ),송희진 ( Hee Jin Song ),인승균 ( Seung Gyun In ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.2
Acantholytic squamous cell carcinoma is a well-defined, rare variant of squamous cell carcinoma in which significant portions of the neoplastic tissue show, on microscopy, a pseudoglandular or tubular pattern. It usually presents in aged patients as an erythematous nodule with scales, crust, and ulceration on sun-exposed areas. Herein we report a case of acantholytic squamous cell carcinoma that occurred on the Rt 4th toeweb of a 70-year-old man. (Korean J Dermatol 2011; 49(2):195~197)
강민지 ( Min Ji Kang ),양보희 ( Bo Hee Yang ),방찬일 ( Chan Yl Bang ),변지원 ( Ji Won Byun ),송희진 ( Hee Jin Song ),최광성 ( Gwang Seong Choi ),신정현 ( Jeonghyun Shin ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.2
Lichen Planus Pigmentosus (LPP), an uncommon variant of lichen planus, is clinically characterized by insidious onset of diffuse or reticulated hyperpigmented patches on the sun-exposed areas and flexural folds. Histopathologic findings of LPP show atrophic epidermis with vacuolar degeneration of the basal cell layer and sparse lichenoid lymphohistiocytic infiltration with melanophages in the dermis. Although there have been few reports of LPP, clinical and histological pathogenesis and prognosis are not well known. Herein, we describe a case of linear LPP along the Blaschko`s lines in 34-year old Korean man who presented with linear hyperpigmented, dark brown patches on his left thigh, repeatedly developing new lesions of erythematous reticular patches since puberty. This report shows the early events of LPP and the protracted course. (Korean J Dermatol 2013;51(2):123∼126)
변지원 ( Ji Won Byun ),양보희 ( Bo Hee Yang ),한성협 ( Sung Hyub Han ),송희진 ( Hee Jin Song ),이현숙 ( Hyeon Sook Lee ),최광성 ( Gwang Seong Choi ),신정현 ( Jeong Hyun Shin ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.3
Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as a polymorphic eruption of pregnancy, is the most common dermatosis of pregnancy. Typically, PUPPP starts with erythema and urticarial papular eruption in the abdominal striae and may extend to the buttocks and thighs. It usually evolves in the third trimester and resolves rapidly in the postpartum. It is not usually recurrent in subsequent pregnancies. We report herein two patients with postpartum PUPPP. (Korean J Dermatol 2010;48(3):228~231)
변지원 ( Ji Won Byun ),양보희 ( Bo Hee Yang ),한성협 ( Sung Hyub Han ),송희진 ( Hee Jin Song ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ),이현숙 ( Hyeon Sook Lee ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.2
Malalignment of the toenail is a rare deformity that is characterized by lateral deviation of the nail plate with respect to the longitudinal axis of the distal phalanx. The condition may be congenital or acquired. The acquired forms of malalignment may result from trauma or surgical intervention. However, there are only a few reports that have focused on surgical treatment for this condition. We present here a case of a 24-year-old woman who had this nail problem for 1 year and she was successfully treated with the surgical approach. We also discuss the probable mechanism of iatrogenic malalignment. (Korean J Dermatol 2010;48(2):148∼151)
방찬일 ( Chan Yl Bang ),변지원 ( Ji Won Byun ),양보희 ( Bo Hee Yang ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ),송희진 ( Hee Jin Song ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.4
Circumscribed palmar or plantar hypokeratosis is a rare dermatosis, and it consists of asymptomatic erythematous, well-circumscribed and depressed patch with scaly borders on the palm or sole. It usually affects middle-aged or elderly women. Histopathologically, it has a sharp stair between the normal and involved skin, and a demarcated area with an abrupt decrease in the horny layer thickness. We report herein a case of circumscribed palmar hypokeratosis that was successfully treated with cryotherapy. (Korean J Dermatol 2011;49(4):345∼347)
문종혁 ( Jong Hyuk Moon ),강민지 ( Min Ji Kang ),방찬일 ( Chan Yl Bang ),양보희 ( Bo Hee Yang ),변지원 ( Ji Won Byun ),최광성 ( Gwang Seong Choi ),신정현 ( Jeong Hyun Shin ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.11
Follicular mycosis fungoides is a distinct variant of mycosis fungoides. Clinically, it occurs mostly in adults, affecting more males than females. It is manifested as pruritic follicular papules, acneiform lesions, or indurated plaques, typically in the head and neck. Histopathologically, it is characterized by infiltration of atypical T lymphocytes with cerebriform nuclei in the follicular epithelium (folliculotropism). We report a case of follicular mycosis fungoides manifested as a milia-like lesion combined with the patch stage of mycosis fungoides, which was treated with radiotherapy (Korean J Dermatol 2013;51(11):901∼904)
Short Report : Acromegaloid Facial Appearance Syndrome with Generalized Hypertrichosis Terminalis
방찬일 ( Chan Yl Bang ),한성협 ( Sung Hyub Han ),변지원 ( Ji Won Byun ),양보희 ( Bo Hee Yang ),송희진 ( Hee Jin Song ),인승균 ( Seung Gyun In ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.2
Acromegaloid facial appearance (AFA) syndrome is a rare autosomal dominant disease, consisting of an acromegaloid face, a bulbous nose, and narrowing of the palpaebral fissure. In 1996, Irvin first reported a case of a combination of acromegaloid facial appearance syndrome and congenital hypertrichosis, and reported this case as a new disease of acromegaloid facial appearance with generalized hypertrichosis terminalis, which is differentiated from both AFA syndrome and congenital hypertrichosis/gingival hyperplasia. We report herein the first Korean case of acromegaloid facial appearance with generalized hypertrichosis terminalis. (Korean J Dermatol 2011; 49(2):184~187)
에이퍼트 증후군에서 Isotretinoin로 치료한 난치성 여드름 1예
변지원 ( Ji Won Byun ),한성협 ( Sung Hyub Han ),양보희 ( Bo Hee Yang ),송희진 ( Hee Jin Song ),이현숙 ( Hyeon Sook Lee ),이승규 ( Seung Gyu Lee ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ) 大韓皮膚科學會 2009 大韓皮膚科學會誌 Vol.47 No.10
Apert syndrome is a rare genetic craniofacial disorder associated with premature fusion of multiple cranial sutures and syndactyly. It is caused by mutation in the fibroblast growth factor receptor 2 genes. The clinical findings are characterized by the typical dysmorphic facial features, including hypertelorism, proptosis and cleft palate. Most of these patients have widespread, severe acne involving the face, chest, back and forearms during puberty and the acne is unresponsive to conventional treatments. We report here on a patient with the recalcitrant acne of Apert syndrome and the patient had failed to respond to conventional acne treatment, but the acne was successfully treated with isotretinoin. (Korean J Dermatol 2009;47(10):1196∼1198)