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김종국(Chong -Kook Kim),원용한(Young Han Won),양지선(Ji Sun Yang),임연수(Yun Su Lim),안혜영(Hae Young Ahn) 한국약제학회 1983 Journal of Pharmaceutical Investigation Vol.13 No.1
Binding of ibuprofenlysine with bovine serum albumin was studied and compared by fluorescence quenching method, difference spectroscopy and circular dichroism. These spectrophotometric methods are indirect measurements which need the probes. So 1-anilinonaphthalene-8-sulfonate was used as a fluorescence spectra probe, 2-(4` hydroxybenzeneazo) benzoic acid as a difference spectrophotometric probe, and sulfaethidole was used as a circular dichroism probe. The results by above three methods were compared and discussed.