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      • 急性膵臟炎의 臨床的 觀察

        安龍承 고려대학교 의과대학 1966 고려대 의대 잡지 Vol.3 No.1

        A clinical study was made of 38 inpatients of acute pancreatitis admitted in the Department of Internal Medicine, Soo Do Medical College Hospital during the period from January, 1961 through December, 1964. The author analysed the medical records of the patients to observe incidence, rates, predisposing factors, cardinal sign and symptoms, especially the initial sites of pains, etc. Observed herein were the serum amylase levels on different stages of illness, the relation of disease improvement with early treatment, and also other laboratory findings and so on. The results obtained were as follows: 1. The sex ratio(male/female) of the total was 1.7. Most cases occurred in the age groups of 20-29 and 30-39 years. Over eating and alcohol intake were the leading causes to induce the attack, occupying 45% of all the cases. Peptic ulcer was found only in 13.2% of the total. 2. The sites for the appearance of initial pain were related in the sequence of epigastrium with 73.6%, right hypochondrium with 7.9%. The most frequent site of radiating pain was the left flank with 14.6% and followed by the back and the right shoulder with 8.3% respectively. Abdominal pain associated with fever and tenderness was most prevailing. The number of the patients with constipation was about as many as four times the cases of diarrhea. One patient was seen lacking any abdominal pain at time of admission. 3. The number of the patients with serum amylase to be more than 400 units was seen in 36.8% within 24 hours after onset of the disease, while 15.8% of the cases checked between 24-56 hours. Two cases(5.3%) were found to have the amylase levels above 400 units 72 hours after the attack. The average unit of the serum amylase for the total patients at times of admission was 596.1, which returned to the normal range on discharge. 4. Moderate leukocytosis and absolute lymphocytopenia were noticed in 68.5% and 37.1% of the total respectively. The mild degree of lymphcytosis was seen in many cases when discharged. 5. The early treatment of the cases always rendered better result. As a whole, most cases of complete recovery and improvement were seen in the age range of 20-49 years, while many cases with complication were noticed in the old age above 50.

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