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- 저자 : 심혜윤 ( Hyeyoon Shim ) (검색결과 2 건)
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수면의 질과 심박변이도, 설진 및 한의학적 문진 결과의 상관성
심혜윤 ( Hyeyoon Shim ),박정환 ( Jeong Hwan Park ),이상훈 ( Sanghun Lee ),김호준 ( Hojun Kim ) 한방재활의학과학회 2022 한방재활의학과학회지 Vol.32 No.1
Objectives We aimed to characterize the results obtained from Korean medical examinations and questionnaires on the quality of sleep. Methods The quality of sleep was measured using the Pittsburgh sleep quality index in 400 subjects. Afterwards, heart rate variability (HRV) measurements were done, along with the analyses for tongue color, teeth marks, and tongue coating through the tongue diagnosis system. A questionnaire about body’s heat, cold and sweating conditions, and the perceived stress scale (PSS) were performed. Finally, correlations between all these indicators and the sleep quality were analyzed. Results As the quality of sleep decreased, the sympathetic nervous system was stimulated. The subjects who had the blue-purple colored tongue experienced decreased quality of sleep. The quality of sleep was also deteriorated in the subjects who usually feel cold and hot easily, sweat a lot, and feel a lot of discomfort. According to the PSS questionnaire, the higher the stress level is, the lower was the quality of sleep. Conclusions We obtained meaningful results by comprehensively analyzing the sleep quality, HRV, tongue diagnosis, heat and cold conditions, sweating, and stress conditions. In particular, the sleep quality had a significant correlation with the rest of the indicators. (J Korean Med Rehabil 2022;32(1):73-87)
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방풍통성산 및 대시호탕의 항비만효과 분석: 단일기관 무작위배정 이중맹검 임상시험 프로토콜
오지홍,심혜윤,차지윤,김호석,김민지,안은경,이명종,이준환,김호준,Oh, Jihong,Shim, Hyeyoon,Cha, Jiyun,Kim, Ho Seok,Kim, Min Ji,Ahn, Eun Kyung,Lee, Myeong-Jong,Lee, Jun-Hwan,Kim, Hojun 한방비만학회 2020 한방비만학회지 Vol.20 No.2
Objectives: The aim of this study is to evaluate the effects of Bangpungtongseong-san (Fangfengtongsheng-san, BTS) and Daesiho-tang (Dachaihu-tang, DST) on weight loss and improvement in lipid metabolism and glucose metabolism. Furthermore, we intend to develop a prediction model for drug effects through the analysis of the single nucleotide polymorphism (SNP), gut-microbiota, and the expression of immune-related biomarkers. Methods: This study is a single-center, randomized, double-blind, parallel-design clinical trial. One hundred twenty-eight participants will be assigned to the BTS group (n=64) and DST group (n=64). Both groups will be administered 4 g medication three times a day for up to 2 weeks. The primary outcomes is weight loss. The secondary outcomes include bioelectrical impedance analysis, waist circumstance, body mass index, total cholesterol, high-density lipoprotein, triglyceride, insulin resistance. The exploratory outcomes include 3-day dietary recall, food frequency questionnaire, quality of life questionnaire, gut microbiota analysis, immune biomarkers analysis, and SNP analysis. Assessment will be made at baseline and at week 4, 8, and 12. Conclusions: This protocol will be implemented by approval of the Institutional Review Board of Dongguk University. The results of this trial will provide a systematic evidence for the treatment of obesity and enable more precise herbal medicine prescriptions.
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