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- 저자 : 서보원(Bo Won Seo) (검색결과 1 건)
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장태원(Tae Won Jang),서보원(Bo Won Seo),김중경(Jung Kyung Kim),정만홍(Man Hong Jung),주운수(Woon Soo Joo),한동선(Dong Sun Han),이재우(Jae Woo Lee) 대한내과학회 1989 대한내과학회지 Vol.36 No.5
N/A To evaluate the effect of chronic alcohol ingestion on heart function, we performed a controlled study with 40 alcoholics and 34 non-alcoholics. The alcoholics ingested more than 90 grams of ethanol per day over 10 years, without any symptoms related to heart failure. Left ventricular size, ejection fraction, fractional shortening, LV mass, systolic time intervals, and transmitral flow velocities were measured by non-invasive methods using EKG, phonocardiogram, carotid pulse tracing, M mode and Doppler echocardiography. The results were as follows 1) Average daily alcohol consumption was 144±80.2 g/day of ethanol in alcoholics and 2.7±5.1 g in non- alcoholics. 2) There were no statistically significant differences in the left ventricular dimensions, ejection fraction, fractional shortening, left ventricular mass and systolic time intervals between the 2 groups. 3) Transmitral flow velocity in alcoholics showed an early peak flow velocity (EPFV) and atrial peak flow velocity (APFV) of 45±9cm/sec and 51.7±9cm/sec, and in non-alcoholics, 51.2±11.4 cm/sec and 46.9±9.3 cm/sec, respectively. Early to atrial peak flow velocity ratio (EPFV/APFV) was 0.895±0.245 in alcoholics and 1.135±0.333 in non-alcoholics, which was statistically significant (p<0.005). The results suggest that left ventricular dysfunciton may present in alcoholics before the development of alcoholic cardiomyopathy and that diastolic dysfunction precedes systolic dysfunction.
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