http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
항 TNF 차단제로 치료한 고령에서 발생한 강직성척추염 증례
이지선 ( Ji Sun Lee ),방소영 ( So Young Bang ),유대현 ( Dae Hyun Yoo ),변영상 ( Young Sang Byun ),박수역 ( Soo Yuk Park ),김태환 ( Tae Hwan Kim ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.1
고령에서 발생한 강직성척추염은 일반적으로 젊은 연령에 비하여 비전형적인 증상들과 고령에서의 퇴행성 변화 및 다른 근골격계 질환의 동반으로 진단이 어렵다. 본원에서 고령에서 다양한 증상으로 발현하여 강직성척추염으로 진단된 4개의 증례들의 임상 양상 및 검사 소견을 이전 연구들과 비교하였으며, NSAIDs, 부신피질호르몬제, DMARDs로 증상과 검사소견의 호전이 없었으나, TNF 차단제를 사용 후 뚜렷한 부작용 없이 호전을 보여 보고하는 바이다. Ankylosing spondylitis is a disease that shows a young age of onset (less than 40 years old), inflammatory back pain, sacroiliitis and a strong association with HLA-B27. Yet some recently reported cases have presented with a late age of onset (more than 55 years old), atypical clinical presentations and a low response to NSAIDs, and this has also been named late onset spondyloarthropathy (LOSPA). As compared with early onset spondyloarthropathy (EOSPA), the LOSPA patients more frequently suffer with combined peripheral arthritis and inflammatory systemic symptoms and a high ESR and CRP level, but they lack the typical axial symptoms. Yet there have been few reports about late onset ankylosing spondylitis (LOAS). The previous cases of LOSPA and LOAS were managed with NSAIDs, steroids, methotrexate and sulfasalazine, but none were managed with TNF antagonists. LOAS is rare and difficult for management because of the patients` older age and the lack of experiences with this malady, so we report here on the four cases of LOAS that were successfully treated by TNF antagonists.
위에서 발생한 선암과 미만성 거대 B세포 림프종의 동시성 중복암
박수역 ( Soo Yuck Park ),은창수 ( Chang Soo Eun ),변영상 ( Young Sang Byun ),윤지영 ( Ji Young Yoon ),전용철 ( Yong Cheol Jeon ),한동수 ( Dong Soo Han ),손주현 ( Joo Hyun Sohn ),오영하 ( Young Ha Oh ) 대한소화기학회 2011 대한소화기학회지 Vol.57 No.2
The simultaneous occurrence of primary gastric lymphoma and adenocarcinoma is rarely reported. We here report a case of synchronous double primary tumor of advanced gastric cancer and diffuse large B cell lymphoma. A 65-year-old woman underwent an esophagogastroduodenoscopy for the evaluation of abdominal discomfort of two months` duration. The endoscopic examination showed an ulcerating tumor in the gastric antrum and thickened folds in the fundus and the microscopic examination revealed an adenocarcinoma in the antrum and a diffuse large B-cell lymphoma in the fundus. She has had total gastrectomy and CHOP chemotherapy with rituximab. Since the cases of synchronous double primary gastric tumors have been increased on the recent medical advances, when a gastric tumor is detected for the endoscopic examination, an endoscopist has to make every endeavor not to miss another tumor in the stomach. (Korean J Gastroenterol 2011;57:115-119)