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- 저자 : 박태군(Tae Koon Park) (검색결과 3 건)
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복수중에서의 혈청 및 복수내 Adenosine Deaminase 활성도 측정의 진단적 가치
박태군(Tae Koon Park),양은수(Eun Soo Yang),박태준(Tae Joon Park),이희승(Hee Seung Lee),류종철(Jong Cheol Ryu),신원창(Won Chang Shin),최원충(Won Chong Choi),이진호(Jin Ho Lee),김관엽(Kwan Yop Kim) 대한내과학회 1994 대한내과학회지 Vol.47 No.1
N/A Objectives: In this study, we would like to evaluate the diagnostic value of adenosine deaminase activity in serum and ascitic fluid from patients with ascites of various causes, including tuberculous peritonitis, liver cirrhosis with or without hepatoma, and cancer peritonitis. Methods: The ADA was assessed in serum and ascitic fluid, and simultaneous calculation of ascitic fluid/ serum ADA ratios were obtained in 89 patients with ascites due to various causes; 42 for liver cirrhosis, 18 for hepatoma, 14 for tuberculous peritonitis, 15 for malignant ascites. Results: 1) Serum ADA activity was significantly higher in patients with liver cirrhosis than those with other causes of ascites, with the level of 61.3±49.0 U/L, and the corresponding ADA levels of other diseases were 42.8±20.4 U/L in hepatoma, 46.1±21.9 U/L in tuberculous peritonitis, 24.0±19.8 U/L in malignant ascites (p<0.05). 2) Ascitic fluid ADA activity was highest in patients with tuberculous peritonitis than those with non-tuber-culous causes of ascites, with the level of 82.0±72.3 U/L, and the corresponding ADA levels of other diseases were 21.1±31.7U/L in liver cirrhosis, 8.8±7.7U/L in hepatoma, 29.0±19.7 U/L in malignant ascites (p<0.05). Ascitic fluid ADA level greater than 80 U/L had a specificity of 97%, sensitivity of 50%, and diagnostic efficiency of 76% for the diagnosis of tuberculous peritonitis. 3) The ascitic fluid/serum ADA ratios were significantly higher in patients with malignant ascites than those with other causes of ascites, with the level of 3.5±7.0, and the corresponding levels of other diseases were 0.8±1.8 in liver cirrhosis, 0.3±0.4 in hepatoma, 1.7±1.3 in tuberculous peritonitis (p<0.05). Conclusion: These results suggest that the assessment of serum and ascitic fluid ADA activity, and simultaneous calculation of ascitic fluid/serum ADA ratios would be useful in the differential diagnosis between patients with tuberculous peritnnitis and non-tuberculous causes of ascites.
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박태준,양은수,류종철,박태군,이희승,신원창,이진호,김관엽 인제대학교 1994 仁濟醫學 Vol.15 No.1
1989년 9월부터 1993년 7월까지 인제대학교 의과대학 상계백병원에서 실시한 위내시경 소견이 조기위암이며 내시경 직시하 생검결과 선암으로 판명되어, 근치적 위절제술을 시행받은 23명의 환자에서 임상적 특징을 알아보고, 문헌고찰과 함께 보고하는 바이다. The incidence and mortality rate of stomach cancer ranks well ahead of all malignancies in Korea. The prognosis is excellent in early gastric cancer of which the overall 5 years survival rate of 85∼95% is comparative with that of advanced gastric cancer of 15∼49%. So early detection with very sensitive mordality of gastroscope and surgery is the only premise to decrease the mortality rate of gastric cancer. This report deals with the clinical aspects of 23 cases of early gastric cancer, which were confirmed with histopathologic examination of resected stomach during the 4 years from September 1989 to July 1993 at Sanggye Paik hospital, Seoul, Korea. Out of 23 cases of early gastric cancer, 14 cases were male, 9 cases were female, and the male to female ratio was 1.6 : 1. The most common type of early gastric cancer was talc type(43.5%), IIc and its combined type comprised most of them(87.0%). The most prevalent sloe of lesion was gastric angle(43.5%) and the most common direction was lesser curvature(73.9%) 19 cases of 23(78.3%) were between 1∼3cm in size, and there was no statistical significance between the size of the lesion and lymph node metastasis. Of the 9 cases with mucosal lesion, there were 2 cases with lymph node metastasis(22.2%), but 7cases(50.0% ) of 14 cases with submucosal lesion presented lymph node metastasis. Diagnostic accuracy of endoscopy on detection of early gastric cancer was 17 cases(73.9%) of total 23 cases in our study. As with other report, histopathulogic examination of resected stomach revealed adenocarcinoma, tubular type as the most common type. Frequent complaint of patients with early gastric cancer was epigastric pain(65.2%), and duration of the symptom was less than 12 months in 17 cases(73.1%) of 23 patients with early gastric cancer.
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