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RISS 인기검색어
- 검색키워드
- 저자 : 박지노 ( Ji No Park ) (검색결과 3 건)
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박지노 ( Ji No Park ),김윤하 ( Yoon Ha Kim ),김철홍 ( Cheol Hong Kim ),조문경 ( Moon Kyoung Cho ),김종운 ( Jong Woon Kim ),박서연 ( Seo Yeon Park ),송태복 ( Tae Bok Song ) 대한산부인과학회 2008 Obstetrics & Gynecology Science Vol.51 No.2
Vasa previa is said to occur when fetal vessels, unsupported by placenta or umbilical cord, transverse the menbranes over the cervix, below the presenting part. It is typically caused by velamentous insertion of the umbilical cord with fetal vessels between the cervix and presenting part. Bilobed or succenturiate placentas also can be associated with aberrant vasculature over the internal cervical os. Vasa previa has an incidence of approximately one per 2000-5000 deliveries. It has a high fetal mortality due to fetal exsanguination resulting from fetal vessels tearing when the menbranes rupture. So Prenatal detection of vasa previa is very important. We believe transvaginal ultrasound in combination with color Doppler is the most effective tool in the antenatal diagnosis of vasa previa. Recently, we experienced one case of vasa previa accompanied by succenturiate placenta diagnosed prenatally by color Doppler and transvaginal sonography. Here we report our experience with a literature review.
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난소암 진단에 있어서 초음파에 의한 형태학적 특성 및 혈관지수의 유용성
이재영 ( Jae Young Lee ),박소정 ( So Jeong Park ),박지노 ( Ji No Park ),기다린 ( Da Rin Ki ),김기민 ( Ki Min Kim ),조문경 ( Moon Kyoung Jo ),김철홍 ( Chul Hong Kim ),김석모 ( Seok Mo Kim ),최호선 ( Ho Sun Choi ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.6
Objective: The aim of this study was to know whether we can distinguish benign from malignant ovarian tumors according to morphologic scoring system (MS), blood flow characteristics (Resistance index (RI), Pulsatility index (PI)) using color doppler sonography and a combination of both in patients undergoing laparotomy or laparoscopy for a clinically diagnosed ovarian mass. Methods: From January 2001 to December 2003, 99 patients with ovarian tumors scheduled for laparotomy or laparoscopy were studied at our institute. Ultrasound was carried out to study the ovarian morphology followed by color doppler sonography. A score of 9 on ≥9 on MS, a PI≤1 or a RI≤0.4 was taken as suspicious for malignancy. Results: A score of ≥9 on MS as indicative of malignancy was associated with the following statistical parameters: sensitivity 69.6%, specificity 69.8%, positive predictive value (PPV) 75.0%, negative predictive value (NPV) 63.8%. A mean score of malignant tumor (9.8±2.64) is significantly higher than that of benign tumor (7.5±2.44). This was statistically significant (p[t]<0.05). A resistance index (RI)≤0.4 was associated with sensitivity 19.6%, specificity 97.6%, PPV 91.6%, NPV 48.2%. A pulsatility index (PI) ≤1.0 was associated with sensitivity 44.6%, specificity 81.3%, PPV 75.7%, NPV 53.0%. A mean of RI in malignancy (0.64±0.277) is lower than that of RI in benign tumor (0.79±0.299). A mean of PI in malignancy (1.34±0.982) is lower than that of PI in benign tumor (2.06±1.310). These was statistically significant (p[t]<0.05). The addition of RI or PI to MS did not improve the accuracy in predicting ovarian malignancy. Conclusion: Although RI or PI achieved better specificity and PPV compared to MS, the addition of RI or PI to MS did not increase its accuracy in the discrimination between benign and malignant ovarian tumors.
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자간전증에서 제대정맥혈장내 interleukin-6, tumor necrosis factor-α, 및 항산화제 농도
김윤하 ( Yoon Ha Kim ),송태복 ( Tae Bok Song ),박소정 ( So Jeong Park ),박지노 ( Ji No Park ),정광필 ( Kwang Pil Jeong ),김종운 ( Jong Woon Kim ),김석모 ( Seok Mo Kim ),김철홍 ( Cheol Hong Kim ),조문경 ( Moon Kyoung Cho ),김기민 ( 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.7
Objective: Our purpose was to investigate Interleukin-6 (IL-6), tumor necrotic factor-α (TNF-α), lipid peroxide levels, oxygen-radical absorbance capacity (ORAC), and antioxidant levels in umbilical venous blood plasma and to evaluate the roles of them in the pathophysiology of preeclampsia. Study design: Samples of umbilical venous plasma were obtained from 20 normal and 20 preeclamptic women between 33 and 40 weeks gestation. IL-6 and TNF-α was assayed by an enzyme -linked immunoassay. Lipid peroxide levels were measured by thiobarbituric acid reaction. The ORAC values were measured by Cao`s method. Ascorbic acid, retinol, α-tocopherol, and γ-tocopherol were measured by high performance liquid chromatography. Results: There was no significant differences of IL-6 levels in umbilical venous plasma between women with normal and preeclampsia (2.79±0.21 vs. 2.94±0.17 ng/ml). TNF-α levels in umbilical venous plasma of women with preeclampsia were significantly higher than that of women with preeclampsia (3.04±0.01 vs. 1.40±0.01 ng/ml, p<0.01). Lipid peroxide levels in umbilical venous plasma of women with preeclampsia were significantly higher than that of women with normal pregnancy (7.32±0.09 vs. 5.18±0.14, p<0.01). The ORAC values in umbilical venous plasma of women with preeclampsia were significantly lower than that of women with normal pregnancy (12,836.5±249.4 vs. 10,490.2±276.9 U/ml, p<0.05). Ascorbic acid levels in umbilical venous plasma of women with preeclampsia were significantly lower than those of women with normal pregnancy (320.2±48.5 vs. 538.5±68.2 nmol/ml, p<0.05). Conclusion: The above results in umbilical venous plasma suggest that the imbalance of lipid peroxidation and antioxidant activity in placenta is involved in the pathophysiology of preeclampsia. Increased TNF-a in the umbilical venous plasma showed inflammatory reaction in the placenta would be one of the cause of preclampsia. An antioxidant vitamin, ascorbic acid, may act an important antioxidant factor in preeclampsia
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