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음향광학변조필터의 이미지 이동 보상을 위한 프리즘 제안
류성윤(Sung Yoon Ryu),유장우(Jang-Woo You),곽윤근(Yoon keun Kwak),김수현(Soo hyun Kim) Korean Society for Precision Engineering 2008 한국정밀공학회지 Vol.25 No.5
The Acousto-Optic Tunable Filter (AOTF) is a high-speed full-field monochromator which generates two spectrally filtered light beams with ordinary and extraordinary polarization state. Thus, AOTF is widely used to build full-field spectral imaging system or spectral domain interferometer. However, AOTF has a big problem that the angle of diffracted light changes according to the scanning of wavelength, which makes image shift on CCD plane. In this paper, we propose an analytic design of prism system to compensate the image shift. The detailed analysis of light paths in a prism and basic experimental results are presented to verify our proposed compensation method. The experimental results agree with simulation results based on suggested prism model and image shift is minimized at optimal condition. Also, it can be extended to compensate the image shift for ordinary and extraordinary polarized light simultaneously.
류성윤 ( Sung Yoon Rew ),고영일 ( Young Il Koh ),신희영 ( Hee Young Shin ),박승환 ( Seong Hwan Park ),류시현 ( Shi Hyun Ryu ),김하나 ( Ha Na Kim ),김민석 ( Min Suk Kim ),천승우 ( Seong Woo Chun ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.3
Background: Since introduction of regional pharmacovigilance centers in Korea, the number of domestic adverse drug reactions (ADRs) reported is rapidly increasing. However, there have been only a few reports on reporting and clinical features of ADRs in Korea. This study was designed to investigate the reporting and clinical features of ADRs reported from a single university hospital. Methods: We included the patients with ADRs reported from a regional pharmacovigilance center of Chonnam National University Hospital between June 2009 and December 2009. ADRs were identified by both voluntary and automated computerized surveillance systems. Additional information was retrospectively collected from electronic medical records and then reporting and clinical features of ADRs were analyzed. Results: Six hundred eighty four ADRs were reported in 446 patients based on both Naranjo`s scale and WHO-UMC criteria. Voluntary reporting consisted of 61.0% of ADRs. Most of ADRs (85.5%) were reported by doctors. Females consisted of 60.4% of patients. The most common clinical manifestations of ADRs were skin symptoms (47.7%), followed by neuropsychiatric (15.5%) and gastrointestinal symptoms (11.5%). The most common offending drugs were anti-infective drugs (30.0%), followed by non-steroidal anti-inflammatory drug (18.1%) and central nervous system agent (12.0%). Conclusion: Doctors can easily report ADRs in our computerized surveillance system. Although it is well known that skin is frequently involved in ADRs and anti-infective drugs and non-steroidal anti-inflammatory drugs induce ADRs, neuropsychiatric symptoms and central nervous system agents should be considered as common manifestations and causative drugs of ADRs, respectively. (Korean J Asthma Allergy Clin Immunol 2011;31:184-191)
다파장 광원을 이용한 위상 물체의 2 차원 굴절률 분포와 두께 측정을 위한 분리 알고리즘
이광천(Kwangchun Lee),류성윤(Sung Yoon Ryu),이윤우(Yun Woo Lee),곽윤근(Yoon Keun Kwak),김수현(Soohyun Kim) Korean Society for Precision Engineering 2009 한국정밀공학회지 Vol.26 No.5
We propose the separation algorithm to simultaneously measure two-dimensional refractive index distribution and thickness profile of transparent samples using three wavelengths. The optical system was based on the Mach-zehnder interferometer with LD (Laser Diode)-based multiwavelength sources. A LCR (Liquid Crystal Retarder) was used to obtain interference images at four phase states and then the optical phase of the object is calculated by four-bucket algorithm. Experimental results with a glass rod are provided at the different wavelengths of 635nm, 660nm and 675nm. The refractive indices of the sample are distributed with accuracy of less than 0.0005 and the thickness profile of sample was cylindrical type. This result demonstrates that it is possible to separate refractive index distribution and thickness profile of samples in two dimensions using the proposed algorithm.