신허요통 환자의 12 경맥 전위측정 연구

남봉현,최환수,Nam, Bong-Hyun,Choi, Hwan-Soo 한국한의학연구원 2003 한국한의학연구원논문집 Vol.9 No.1

Objectives : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea(合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 16 patients with Lumbago due to the kidney deficiency(腎虛腰痛, LKD), to find out the characteristic of meridian system in patients with LKD. Methods : Electric potentials of welt and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as LKD were repeatedly measured by physiograph(PowerLab). Measurements of those electrical potentials were analyzed by factor analysis. Results : The electric potentials of WSBTM at the left side were divided into five factors. On the other hand those at the right side Were divided into t1vee factors. Conclusions : In conclusion, their electrical potentials at the left and right side were four different factors search side. Thus electrical potentials of welt and sea points might be the representative meridian to show their characteristics.

12 경맥 전위측정 실험에 대한 연구(2) -정상인과 뇌경색환자의 측정전위 비교-

남봉현,최환수,Nam, Bong-Hyun,Choi, Hwan-Soo 대한침구의학회 2000 대한침구의학회지 Vol.17 No.3

Objectives : The characteristic of meridian system has been similar to this of electric potentials in human body. Therefore to measure the electric potentials in healthy volunteers and patients, and to find out the characteristic of meridian system and also to do that of differences between them. Methods : Twenty-nine healthy volunteers, thirty patients diagnosed as a cerebral infarction and wind-syndrome caused by hyperactivity of the liver-yang(肝陽化風) were examined into electric potential of well(井穴) and sea(合穴) points in branches of the twelve meridians by physiograph. Results : Measurements were analyzed by factor analysis, then we obtained that both the right and the left electric potential of well and sea points in branches of the twelves meridians in healthy volunteers were divided into two factors, hand meridian and foot meridian. Where as the left electric potential of those in patients with cerebral infarction were divided into three factors, one is foot meridian, another is hand meridian with the exception of large intestine meridian, and the other is large intestine meridian and also the right electric potential were divided into three factors, foot meridian, hand meridian with the exception of large intestine and lung meridian, and large intestine and lung meridian. Conclusions : In the results, healthy volunteers differ from patients in characteristic of electrical potentials, which means that we are able to catch the characteristic of meridian system by electrical potentials of well and sea points.

산재입원환자의 한방의료서비스 요구도 조사

남봉현,Nam, Bong-Hyun 한국한의학연구원 1995 한국 한의학연구소 논문집 Vol.1 No.1

The oriental medicine has played the basic roles in national bealth care system in Korea. but the oriental medicine is excluded from medical system in some part. This paper examines the oriental medical needs to the impatients who met with the industrial accident. The results show that the impatients have a relatively positive recognition of oriental medicine.

12경맥 전위측정 실험에 대한 연구(3) -부정맥 환자의 측정전위 비교-

남봉현,최환수,Nam, Bong-Hyun,Choi, Hwan-Soo 대한침구의학회 2000 대한침구의학회지 Vol.17 No.4

Objectives : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea(合穴) points in branches of the twelve meridians will be representative of measurements of the twelve meridians, to measure the electric potentials in three patient groups with arrhythmia(AP group), with arrhythmia and cerebral infarction(CI group), and with arrhythmia and hemorrhage(CH group), and then to find out the characteristic of meridian system among 3 groups. Methods : Thirty arrhythmic patients diagnosed by EKG, CT, and deficiency of the heart blood(心血虛症) were divided into 3 groups(AP, CI, CH group). Their electric potential of well and sea points in the meridians were measured 3 times by physiograph. Results : Measurements were analyzed by statistical factor analysis, we obtained that the left side electric potential of well and sea points in branches of the twelves meridians in AP group was divided into two factors, which were the hand meridian without the lung meridian, the foot meridian and the lung meridian, but the right side electric potential was divided into the hand and the foot meridian. In CH group both the left and the right side electric potential was divided into three factors. In CI group the left side electric potential was divided into three factors, but the right side electric potential was divided into two factors. Conclusions : In conclusion, their electrical potentials were different each other among 3 groups. Thus electrical potentials of well and sea points might be the representative meridian to show their characteristics.

통증에 따른 경락의 생체 물리적 정보 분석 연구

남봉현 ( Bong Hyun Nam ),테드캡척 ( Ted J. Kaptchuk ) 대한경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.4

Objectives: Although previous anatomic, physiological and biophysics studies have examined the acupuncture meridian system, much remains unclear and controversial. This study was undertaken to examine electrical potential aspects of the meridian system. Electric potential was measured at the well and sea acupoints on the twelve acupuncture meridians (AM), on forty patients half with loin lesions, and pain of loin and lower extremities(LL) and half with shoulder lesions, and aching of shoulder and arm(SA). The object was to determine to what extent electric potential is an important risk factor between LL and SA. Methods: At the left and the right side with each of twenty LL and twenty SA patients, physiograph was used to measure electric potentials of AM ten sessions. T-test was used to compare the mean of electric potential between the two different pain groups and multiple logistic regression was used to analyze the risk of the 24 electric potentials measured. Results and Conclusions: In the LL, the only electric potential that was statistically significantly greater than SA was the bladder meridian on the left side. On the contrary, electric potentials in SA, which includes the large intestine, pericardium, triple burner, spleen, stomach, kidney and gallbladder meridians, were statistically larger than those of LL at the same side. On the right side, the five kinds of electric potentials(lung, large intestine, small intestine, pericardium and gallbladder meridians) of LL were statistically Larger than those of SA. On the triple burner, stomach and kidney meridians electric potentials of SA were larger than those in LL. After adjusting for 24 electric potentials, pain risk factors, and different illness categories, multiple stepwise selection logistic regression modeling, resulted in the final selection of a total of 13 statistically significant electric potentials. These were 7 electric potentials at Left side-small intestine, triple burner, spleen, stomach, bladder, liver and gallbladder meridian, and 6 at right side-lung, large intestine, heart, pericardium, kidney and bladder meridian.

경락 전위를 이용한 경락의 생체물리학적 연구

남봉현 ( Bong Hyun Nam ),최환수 ( Hwan Soo Choi ) 대한경락경혈학회 2002 Korean Journal of Acupuncture Vol.19 No.2

Objectives: Assuming That the Characteristic of Meridian System Has Been Similar to This of Electric Potentials in Human Body and That Measurements of Electric Potential at Well and Sea Points in Branches of the Twelve Meridians Will Be Representative of Measurements of the Twelve Meridians, to Measure the Electric Potentials in Healthy Volunteers(HG), Patients Diagnosed As a Cerebral Infarction(CG), a Arrhythmia(AG), a Other Intervertebral Disc Disorders(IG), and a Joint Disorder(JG), and Then to Find Out the Characteristic of Biophysical Meridian System, Finally to Compare with the Results of the Electric Potentials in Those Groups. Methods: We Selected Who HG Were Diagnosed by a Blood Test, Urine Examination and Differentiation of Syndromes by Five Viscera among Volunteers, CG by CT and Wind-Syndrome Caused by Hyperactivity of the Liver-Yang, AG by EKG, CT, and Deficiency or the Heart Blood, IG by X-ray or CT and Pain in Waist, and JG by X-ray and Knee Pain. Their Electric Potential of Well and Sea Points in the Meridians Were Measured by Physiograph. Results and Conclusions: Measurements Were Analyzed by Factor Analysis, Analysis of Variance, and Logistic Regression Model, We Obtained That Most of the Results, in Conclusion, Hold Good for the Classical Meridian Doctrine.

한약의 약성 ( 사기 ) 에 대한 현대적 검증 (1) - 체온과의 상관성 -

남봉현(Bong Hyun Nam),이미영(Mi Young Lee),김정숙(Chung Sook Kim),이한구(Han Goo Lee) 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.1

The odor theory(氣味論) has been defined as the Nature(氣) and the Taste(味) of traditional herbal medicine to find the logic in treatment of various diseases by them. There is a strong possibility these Natures of the drug can be categorized according to yin (陰) and yang (陽). There is a neutral Nature which does not fit into one of these four categories. To understand the Natures of traditional herbal drugs in modern scientific approaches, changes in rectal temperature of rats have been measured at 0, 30, 60, 90 min after a 10 g/Kg oral administration each of 34 different drugs. Following the classification of the four Natures of drugs, only the temperatures of warm group at 30, 60, and 90 min were elevated significantly from the control and the rest groups. Following a modified classification of 3 groups such as cold and cool, warm and hot, and neutral Nature, changes in temperatures after administration of Hot and Warm drugs were also increased significantly from the control (P<0.01). Thus, the measurement of rectal temperature can be a tool to define the Nature (氣) of traditional herbal drugs, but the modified classification is another way to do.

생물학적 동등성 시험의 추가시험에 대한 통계적 고찰

박상규,남봉현,정윤노,이재영,정규진,Park, Sang-Gue,Nam, Bong-Hyun,Chung, Yun-Ro,Lee, Jae-Young,Jeong, Gyu-Jin 한국통계학회 2010 Communications for statistical applications and me Vol.17 No.1

제제간의 생물학적 동등성을 입증하는데 실패했을 때 추가시험을 허용하는 새로운 생물학적 동등성 시험 기준이 2008년 7월부터 시행하게 되었다. 추가시험의 의미나 시험 기준에서 제시하는 절차를 살펴보고 추가시험의 통계학적 의미를 고찰한다. 또한 사례를 통해 추가시험을 고려할 경우 어떤 점에 유의하여야 성공 할 수 있을 것인가 논의한다. The newly revised bioequivalence guideline of Korea allows the add-on test since July 1, 2008 and some discussion from statistical point of view would be needed for a practical use. The statistical model of add-on test is introduced and its two stage testing procedures are discussed. Meaningful statistical points of the add-on test are delivered through an illustrated example.

구안와사 환자의 12경맥 전위측정 연구

최환수,남봉현,Choi, Hwan-soo,Nam, Bong-hyun 대한침구의학회 2004 대한침구의학회지 Vol.21 No.6

Objective : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea (合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 13 patients with Facial Hemiparalysis (구안와사<口眼蝸斜>, FH), to find out the characteristic of meridian system in patients with AK. Methods : Electric potentials of well and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as FH were repeatedly measured by physiograph(PowerLab). Measurements of those electrical potentials were analyzed by factor analysis. Results : The electric potentials of WSBTM at the left side were divided into five factors. On the other hand those at the right side Were divided into four factors. Conclusions : In conclusion, their electrical potentials at the left and right side were each other five and four factors. Thus electrical potentials of well and sea points might be the representative meridian to show their characteristics.

좌섬요통 환자의 12경맥 전위측정 연구

최환수,남봉현,Choi, Hwan-soo,Nam, Bong-hyun 대한침구의학회 2004 대한침구의학회지 Vol.21 No.5

Objective : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea (合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 13 patients with Lumbago due to strain and contusion(좌섬요통<挫閃腰痛>, LSC), to find out the characteristic of meridian system in patients with LSC. Methods : Electric potentials of well and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as LSC were repeatedly measured by physiograph(PowerLab). Measurements of those electrical potentials were analyzed by factor analysis. Results : The electric potentials of WSBTM at the left side were divided into four factors. On the other hand those at the right side Were divided into four factors. Conclusion : In conclusion, their electrical potentials at the left and right side were factors which are different from each side. Thus electrical potentials of well and sea points might be the representative meridian to show their characteristics.