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영아 연축과 Lennox-Gastaut 증후군을 동반한 Miller-Dieker 증후군 1례
나정민(Jeong Min Na),박찬희(Chan Hee Park),유은정(Eun Jung Yoo),정권(Kwon Jung),김경심(Kyoung Sim Kim),김용욱(Yong Wook Kim),김은영(Eun Young Kim) 대한소아신경학회 2008 대한소아신경학회지 Vol.16 No.1
근간대성 경련을 주소로 내원한 11일된 여아로, 1형 활택뇌증과 특징적인 안면 이상, FISH에서 17p13.3의 미세 결실을 보여 Miller-Dieker 증후군으로 진단되었다. 경련은 4개월에 영아 연축, 3년 6개월에 Lennox-Gastaut 증후군으로 진행되었고, 항경련제에 의해 잘 조절되지 않았다. 현재 환아는 8세로, 심한 정신 운동 발달 지연과 심한 성장 부진을 보인다. 저자들은 난치성 간질을 동반하면서 장기간 생존해 있는 증례를 경험하였기에 문헌고찰과 함께 보고하며, 유전학의 최근 진전, 동반 간질, 유전상담을 중점적으로 기술하고자 하였다. Miller-Dieker syndrome is a contiguous gene deletion syndrome involving chromosome 17p13.3, which is characterized by type 1(classical) lissencephaly and typical craniofacial abnormalities. Children with Miller-Dieker syndrome have profound psychomotor retardation, seizures that often are intractable, chronic feeding problems that lead to recurrent pneumonia, and shortened lifespan. We have experienced a Miller-Dieker syndrome female who has lived to 8years, showing severe mental and motor retardation and intractable epilepsy. She was diagnosed as Miller-Dieker syndrome in the neonatal period, showing typical facial features, type 1 lissencephaly, and chromosome 17p13.3 microdeletion in fluorescence in situ hybridization. Infantile spasm occurred at 4 months of age and progressed to Lennox-Gastaut syndrome at 3 years and 6 months, both of which were not controlled by antiepileptic drugs.
고장력 인장봉으로 보강한 RC보의 인장철근비에 따른 보강 효과에 관한 연구
김윤정(Kim Yoon-Jung),신경재(Shin Kyung-Jae),문정호(Moon Jeong-Ho),오영석(Oh Young-Suk),나정민(Na Jeong-Min) 대한건축학회 2007 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.27 No.1
The objectives of this study are to check the flexural capacities of RC beams strengthened with unbonded high-tension bars and to provide the test results applying the strengthening design. The advantages of proposed strengthening method consist in speed and simplicity of installation and strengthening performance independent from skilled worker. A set of ten laboratory tests on RC beams strengthened with high-strength bars is reported. The main test parameters are the diameter of high-strength bar and the ratio of tension reinforcement. Applied prestress ratio of high-tension bar is 40% of nominal yield stress of high-tension bar. There are some cases that unbonded strengthening member doesn't yield, the present experiment appied 40% of prestress shows that the strain high-tension bars of all RC beam specimens was more than yield strain. Additionally, the trend of flexible behavior according to the ratio of tension reinforcement is at one with analytical result calculated with general design equation. Hence, it is possible to calculate nominal moment of RC beam strengthening with high-tension bars.