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Dantrolene Sodium이 간 조직내 Sulfhydryl Group과 Glutathione에 미치는 영향
김광국,백광세,강복순,Kim, Kwang-Kook,Paik, Kwang-Sea,Kang, Bok-Soon 대한생리학회 1985 대한생리학회지 Vol.19 No.2
Dantrolene sodium(DS) is a long acting skeletal muscle relaxant which has been successfully used to control muscle spasticity in patients with various neurological disorders. However, its use is associated with hepatotoxicity. Tissue sulfhydryl group has many important roles for cellular integration and glutathione serves as a substrate for the detoxification metabolism. The purpose of this study were to investigate the effect of DS on tissue sulfhydrl group and glutathione content. Foully albino rats were divided into two groups ; saline treated (control) and DS treated groups. DS dissolved in saline was administered orally. All rats were sacrificed after 7. 14. 21 and 28 days of DS ana saline treatment by dacapitation ana liver was removed for the enzyme preparation. Total and nonprotein sulfhydryl were measured by the method of Sedlak and Lindsay (1968). Total glutathione content was assayed according to the method described by Tietze (1969) and glutathione reductase was assayed according to the method of Racker (1955), The results obtained are summarized as follows : DS administration significantly depressed the total, protein and nonprotein sulfhydryl content in liver. There were significant reduction of both total glutathione content and glutathione reductase activity in liver. On the basis of the above results it may be speculated that the toxicity of DS are well correlated with tissue sulfhydryl content and glutathione reductase activity.
사용자 리뷰 토픽분석을 활용한 모바일 쇼핑 앱 고객만족도에 관한 연구
김광국(Kwang-Kook Kim),김용환(Yong-Hwan Kim),김자희(Ja-Hee Kim) 한국전자거래학회 2018 한국전자거래학회지 Vol.23 No.4
현재 모바일 쇼핑 시장의 빠른 성장에도 불구하고 주요 사업자들은 심한 경쟁 속에서 지속적인 영업적자를 기록하고 있다. 이 문제를 해결하기 위해서는 모바일 쇼핑 시장은 과도한 경쟁보다는 고객만족도와 고객충성도를 높이기 위한 연구들이 요구된다. 그러나 기존의 연구들은 기술수용 모형과 문헌연구를 기반으로 요인을 추출하고 있어 고객의 직접적인 요구를 반영하는 데 한계가 있다. 본 연구는 모바일 쇼핑 앱 사용자들의 직접적인 요구사항을 도출하기 위하여 사용자 리뷰 토픽분석을 시행하여 고객만족도에 영향을 미치는 구체적이고 다양한 요인들을 도출하였다. 그리고 미국 고객만족도 지표 모형을 참조한 구조방정식 연구모형을 수립하여 도출된 요인들이 고객만족도에 미치는 중요도를 평가하고 고객만족도가 고객 불평과 고객충성도에 주는 영향을 실증 분석하였다. 본 연구에서 제안한 토픽분석과 구조방정식을 연계한 연구 프레임워크는 다른 모바일 서비스의 고객만족도 연구에도 적용될 수 있을 것으로 기대된다. Despite the rapid growth of the mobile shopping market, major market participants are continuing to suffer operating losses due to severe competition. To solve this problem, the mobile shopping market requires research to improve customer satisfaction and customer loyalty rather than excessive competition. However, the existing studies have limits to reflect the direct needs of customers because they extract the factors on the basis of the Technology Acceptance Model and the literature study. In this study, to reflect the direct requirements of users of mobile shopping Apps, we derived concretely and various factors influencing customer satisfaction through a topic analysis using user reviews. And then we assessed the importance of derived factors to customer satisfaction and analyzed the effects of customer satisfaction on customer complaints and customer loyalty on a structural equation model based on the American customer satisfaction index. We expect that our framework linking a topic analysis and a structural equation model is to be applicable to studies on the customer satisfaction of other mobile services.
김광국(Gwang-kook Kim) 한국기업법학회 2007 企業法硏究 Vol.21 No.4
This is a study on the liability of the insurer in the covered vehicle assignment clause. The rights and duties of the named insured may not be assigned to an assignee without the insurer's consent under the auto insurance standard policy in Korea, and the policy does not cover the loss of the accident which the assignee causes after the named insured has the covered vehicle over to the assignee. However, even though the assignee causes the accident after the named insured surrenders the covered vehicle over to the assignee, where the named insured has responsibility to compensate to the victim the bodily injury liability coverage should provide protection for the named insured. But in this case the other coverages such as the property damage liability coverage, the medical payments coverage and the insured auto damage coverage do not provide protection for the named insured and the assignee. This is because the named insured would not get any loss from the accident provided in the coverages after the named insured surrenders the covered vehicle over to the assignee. And the compulsory auto liability coverage provide protection for the assignee for 15 days after the named insured has the covered vehicle over. If a named insured shown in the declarations dies coverage will provided for the legal successor of the deceased person.
지역산업 육성 및 활성화를 위한 지방투자지원제도 개선방안 연구
김광국(Kim Kwang Kuk),백승기(Baek Seung Gi),황지욱(Hwang Jee Wook) 한국지역개발학회 2016 韓國地域開發學會誌 Vol.28 No.1
Local investment promotion subsidy (hereinafter, Subsidy) scheme, started in 2004 with the aim of supporting the relocation of the metropolitan area businesses has been expanded to newly-established and extended local area businesses. Its project budget also continues to increase. The aim of this study was to analyze the problems of its budget execution from the institutional aspects, and to find out how to improve the implementation of budget execution and how to rearrange its institutional framework. In the analysis of subsidy implementation performance, the 3 top issues could be identified as followed: largely the institution of the subsidy alone is not enough to induce or achieve the balanced regional development effectively; the effect of invigorating the local economy is very limited due to the businesses concentration in the metropolitan area; the regional bias of the subsidy volume fundamentally showed the limit of eliminating the regional unbalance. As the result of this analyzed evaluation on the subsidy execution and propulsion performance, the current subsidy support system for effectively supporting and promoting the local businesses and industries needs to be institutionally and methodically improved. First, based on the political principle of selection and concentration it is important to enhance the local businesses and to promote the indigenous local industry. Second, it is needed to scale up the volume of the subsidy budget considering the industrial needs and local economic circumstances. Third, the autonomy, security and surveillance of local government operating the subsidy have to be enhanced. And fourthly, based on the shortand long-term investment strategy the enhancement of the local investment is required.