소양인처방(少陽人處方) 활용(活用)에 대한 임상적(臨床的) 연구(硏究)

구덕모,Goo, Deok-Mo 사상체질의학회 2005 사상체질의학회지 Vol.17 No.2

1. Objectives Due to a lack of detail guidelines for prescriptions to ordinary and pathological symptoms in ${\ulcorner}$DongyiSuseBowon${\lrcorner}$, doctors depend on their own decision when give a prescription. This study aimed to compare ordinary symptoms and pathological symptoms in regards to six prescriptions being applied to Soyangin to utilize them as guidelines in practices. 2. Methods Date were collected from September, 2003 to August, 2004 at the Sasang Constitutional clinic of Pohang Oriental Medicine Hospital. Patients were first asked to fill Out a questionnaire of symptoms that they had at the time of visiting. Data from 273 Soyangin patients whose chief complains got alleviated after taking the prescribed drug were analyzed to examine if there were differences in prescriptions according to ordinary or pathological symptoms complained. 3. Results and Conclusions 1. Hyungbangpaedog-san(Paedog) was given more to the patients having good digestive function than Hyungbangjihwang-tang(Hyungji) and Hyungbangdojeok-san (Dojeok) ; Dojeok was given for bloating symptom compared to Hyungbangsabaek-san(Sabaek). Yangkyuksanhwa-tang(Yangkyuk) and Dojeok were more like for patients with stomachache compared to Paedog. Doghwaljihwang-tang(Dogji) was prescribed to patients complaining frequent voiding compared to Sabaek while Sabaek was given for patients who prefer cold water and feel their body warm compared to other prescriptions. Yangkyuk and Dojeok were prescribed more likely to patients with feeling of suffocation than Sabaek. 2. In symptom comparisons between one prescription and the group of the rest of 5 prescriptions, Paedog was found to be prescribed when patients had good digestive function while Dojeok was given in symptoms cases of indigestion, bloating, constipation and dizziness. Sabaek was applied more for patients having tendency of preferring cold water and feeling of heat body as well as good digestive function. Hyungji was used for patients complaining a symptom of fatigue, in addition Yangkyuk was given to patients who were nervous, sensitive, or impatient when compared to Other prescriptions. Dogji was applied to frequent voiding, insomnia, tingling of extremities, backache or leg pain, or in case of tendency of catching a common cold.

사상체질방으로 간질환 후유증을 호소하는 소양인(少陽人) 치험 1례

구덕모 ( Deok Mo Goo ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.4

Objectives: The purpose of this case study is to report the improvement after Sasang Constitutional treatment to patient who has liver disease sequelae. Methods: This patient was treated by Soyangin`s Constitutional Medications according to the result of Sasang Constitutional diagnosis. We checked visual analog scale(VAS) to evaluate the symptoms of liver disease sequelae. Results: The general condition of the patient improved by the end of hospitalization. The visual analog scale(VAS) of general weakness dropped from 10 to 3. Other symptoms also showed improvement. Conclusions: This case study shows Sasang Constitutional treatment has effectiveness on liver disease sequelae.

수화기제탕(水火旣濟湯)이 주령별 흰쥐의 혈청과 테스토스테론에 미치는 영향

이정환,구덕모,안택원,Lee, Jung-Hwan,Goo, Deok-Mo,Ahn, Taek-Won 사상체질의학회 2010 사상체질의학회지 Vol.22 No.4

1. Objectives The purpose of this study is to investigate the effects of oral administration of distilled Suhwagije-tang in aging rats. 2. Methods The SD rats used in this experiment were 6, 48 and 68 weeks old. These groups were treated with distilled water(DW), 1% Vitamin C(Vit. C) and 50% Suhwagije-tang(SGT) distillate respectively, once a day for 4 weeks. Blood samples were taken from heart and the levels of various parameters in serum were analysed. 3. Results and Conclusions (1) At all concentration of SGT, survival rates of liver cells were higher than the control group. (2) The rate of which the 10W-SGT group gained weight was significantly higher than that of the control groups. (3) The levels of albumin in serum of 10W-SGT group were significantly increased in comparison to those of the DW group. The levels of ALP, total cholesterol and HDL-cholesterol in serum of 52W-SGT group were significantly decreased in comparison to those of the DW group. (4) The levels of testosterone in serum of SGT groups showed no significantly changes in comparison to those of the control groups. Testosterone levels were naturally decreased with advancing years, so 72W-DW group's testosterone level was significantly decreased in comparison to those of 10W-DW group's. In contrast, 72W-SGT group's level was the highest in comparison to those of the control groups and those of deviation from 10W, 52W and 72W in SGT groups was also smaller than control groups'. (5) The levels of glucose, total-bilirubin, ALT, AST, BUN, CRP, hs-CRP, homocystein, Na, K, Na/K ratio, Cl and Ca in serum of SGT groups showed no significantly changes in comparison to those of the control groups. These results suggest that oral administration of Suhwagije-tang distillate should be effective in promoting growth and preventing rapid decline of testosterone in aging rats does not cause any imbalance in liver, kidney and electrolyte.

그레이브스병으로 진단된 소음인의 팔물군자탕과 양약 병용 투약한 치험 1례

이승협,최애련,구덕모,Lee, Seung-Hyeob,Choi, Ae-Ryun,Goo, Deok-Mo 사상체질의학회 2010 사상체질의학회지 Vol.22 No.4

1. Objectives The purpose of this case is to report that Soeumin patient diagnosed as Grave's disease was treated with Palmulgunja-tang and antithyroid drugs in combination. 2. Methods From April 7, 2010 to June 30, 2010, we treated him with Palmulgunja-tang and antithyroid drugs. We took his weight, pulse and checked visual analog scale(VAS) to evaluate the symptoms of Grave's disease. 3. Results After treatment, this patient's thyroid function test were improved faster than with western medicine treatment only in 2009. The symptoms also were improved. 4. Conclusions This case study showed an efficient results by giving Sasang Constitutional treatment in treatment of Grave's disease.

자궁근종(子宮筋腫) 및 난소낭종(卵巢囊腫)으로 진단(診斷)받은 소양인(少陽人) 환자(患者) 치험예(治驗例)

이정환,박석준,구덕모,이상민,서은희,Lee, Jung-Hwan,Park, Suk-Joon,Goo, Deok-Mo,Lee, Sang-Min,Seo, Eun-Hee 사상체질의학회 2005 사상체질의학회지 Vol.17 No.1

1. Objectives Uterine myoma and Ovary cyst is a common disease in gynecologist. These disease can also be treated by Sasang constitutional medical diagnosis and treatment. 2. Methods In treatment of the patient who has Uterine myoma and Ovary cyst, we had diagnosed her as soyangin by their own characters and prescribed Gamijihwang-tang(加味地黃湯). 3. Results The scale of Uterine myoma and Ovary cyst reduced and the occured syndrome with that disease was diasppeared 4. Conclusions In conclusion, this paper shows that the treatment and healing process of Uterine myoma and Ovary cyst.

자세변화에 따른 현훈(眩暈)을 주소증으로 한 태음인(太陰人)환자 치험 3례

이정환,서은희,하진호,초재승,구덕모,Seo, Eun-Hee,Ha, Jin-Ho,Cho, Jae-Seung,Goo, Deok-Mo 사상체질의학회 2007 사상체질의학회지 Vol.19 No.1

1. Objectives These cases are to report that Taeumin patients suffering from positional vertigo treated by Constitutional medications. 2. Methods These patients were treated by Taeumin's Constitutional medications and acupuncture treatment according to the result of Sasang Constitutional diagnosis. We used Visual analogue scale(VAS) for the assessment of vertigo. 3. Results & Conclusions Three patients have been suffering from Positional Vertigo were treated by Taeumin's Constitutional medications(especially Taeumjowi-tang and Jowisungcheng-tang) and showed positive responses about their problems.

양격산화탕(凉隔散火湯)으로 호전(好轉)된 소양인(少陽人) 외전신경마비(外轉神經痲痺) 사시환자(斜視患者) 치험 1례

최애련,하진호,이정환,장우석,구덕모,Choi, Ae-Ryun,Ha, Jin-Ho,Lee, Jung-Hwan,Jang, Woo-Seok,Goo, Deok-Mo 사상체질의학회 2008 사상체질의학회지 Vol.20 No.3

1. Objectives The purpose of this case study is to evaluate the effects of Yangkyuksanhwa-tang which is based on Sasang Constitutional Medicine for strabismus of abducence nerve paralysis. 2. Methods This patient was created by Soyangin's Constitutional Medications according to the result of Sasang Constitutional diagnosis. We evaluated the abduction deficit that described how to use Scott and kraft. 3. Results & Conclusions This case study shows an efficient result of using Yangkyuksanhwa-tang in treatment of Strabismus of abducence nerve paralysis.

Allergy 비염 환자에서 분리된 Klebsiella pneumoniae 289에 대한 소음인(少陰人) 보중익기탕(補中益氣湯), 곽향정기산(藿香正氣散) 및 궁귀향소산(芎歸香蘇散)의 항균효과

서지용,서은희,박석준,구덕모,Suh, Ji-Yong,Seo, Eun-Hee,Park, Suk-Joon,Goo, Deok-Mo 사상체질의학회 2004 사상체질의학회지 Vol.16 No.3

1. Objectives Although the incidence of allergic rhinitis is increasing continually, Sasang Constitutional Medicine is showing favorable treatment outcomes. This study was aimed to test the antimicrobial effects of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san which are being applied to allergic rhinitis of Soeumin. 2. Methods Klebsiella pneumoniae 289 was extracted from allergic rhinitis patients. Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were boiled down and concentrated, and the substances obtained were tested for the effects on stability to temperature and pH and on antimicrobial activity 3. Results When measured the level of antimicrobial activity, the inhibition zones of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were found 11.42, 11.07, and 10.63mm, respectively. The levels of MIC were $15{\mu}{\ell}$, $20{\mu}{\ell}$, and $10{\mu}{\ell}$ in that order. The antimicrobial activities were increased 13.88% in Bojungikgi-tang, 16.63% in Gwakhyangjeonggi-san, and 10.72% in Gunggwihyangso-san. There was no influence of pH to antimicrobial activity of all three substances. 4. Conclusions Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san had a high level of antimicrobial activity to Klebsiella pneumoniae 289 even at a low concentration.

사상체질별 혈중 호모시스테인에 관한 연구

서은희,하진호,서영호,박석준,구덕모,이정환,Seo, Eun-Hee,Ha, Jin-Ho,Seo, Young-Ho,Park, Suk-Joon,Goo, Deok-Mo,Lee, Jung-Hwan 사상체질의학회 2006 사상체질의학회지 Vol.18 No.1

1. Objectives The purpose of this research is to find out the Constitutional difference between the amount of Plasma Homocysteine, Total cholesterol, and Triglyceride which are factor of Cerebrovascular disease. 2. Methods We enrolled 132 patients inexperienced Strokes who visited our hospital for a medical examination from April 26, 2004 to June 29, 2005 except patients whose body constitusions were undetermined according to QSCOII. This research investigated the Constitutional difference between the amount of Plasma Homocysteine, Total cholesterol and Triglyceride. 3. Results & Conclusions This research has shown that there is a statistical significance between the average amount of Plasma Homocystein level that is higher in Taeumin. But there is no significant difference between the average amount of Total Cholestrol and Triglyceride in Sasang Constitution.

사상체질에 따른 신체적, 심리적 특성의 연구

서은희,최애련,하진호,채한,김판준,구덕모,Seo, Eun-Hee,Choi, Ae-Ryun,Ha, Jin-Ho,Chae, Han,Kim, Pan-Joon,Goo, Deok-Mo 사상체질의학회 2009 사상체질의학회지 Vol.21 No.3

1. Objectives: The purpose of this study was to analyze the physical and psychological characteristics of each Sasang type groups which were classified by Sasang medicine specialist. 2. Methods: The subjects were 115 (85.2% of male) university students with $26.8\pm5.4$ yrs. of age and $12.9\pm1.7$ yrs. of education. We can get 30 of Soyang type, 39 of Taeeum type, 46 of Soeum type after the Sasang type classification. Their physical characteristics were measured with Bioelectrical Impedance Analysis (Inbody 720, Biospace, Seoul), and psychological characteristics with Temperament and Character Inventory (Maumsarang, Seoul). The general linear model (SPSS 12.0, SPSS Inc, Chicago) were used for the analysis with gender and age as covariance. 3. Results and Conclusions: Taeeum type group ($75.64\pm13.01$, $26.12\pm4.16$, $15.74\pm2.42$, $11.30\pm1.80$, $3.93\pm0.62$, $18.43\pm7.70$) showed significantly bigger weight, intra-cellular water, extra-cellular water, protein, mineral, body fat mass than Soeum type group ($61.32\pm8.56$, $22.54\pm3.87$, $13.70\pm2.15$, $9.74\pm1.68$, $3.35\pm0.51$, $10.79\pm3.97$). In obesity degree such as Body Mass Index and Waist-hip ratio, and circumference measures in chest, waist and hip, we found significant differences in the order of Taeeum>Soyang>Soeum. As a psychological perspectives Soyang type group ($41.90\pm13.32$) has higher NS (Novelty-Seeking) score than Soeum type group ($35.22\pm11.22$) with marginal significance (p=0.052). In sub-scale measurements Soeum type group ($10.61\pm3.69$) has significantly lower value than other two groups in P3 (Ambition). The results of present study showed that Taeeum type by specialist has same physical characteristics as previously reported QSCC II based studies. Temperament profile of each Sasang type group will serve as an important evidence for further study showing that the Sasang typology has biological basis.