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폐렴간균에 의한 감염성 대동맥류와 동반된 내인성 안내염
오세훈 ( Se Hoon Oh ),이미래 ( Mi Rae Lee ),백경란 ( Kyong Ran Peck ),강세웅 ( Se Woong Kang ),최연현 ( Yeon Hyeon Choe ),김영욱 ( Young Wook Kim ),김덕경 ( Duk Kyung Kim ) 대한내과학회 2010 대한내과학회지 Vol.78 No.3
A mycotic aneurysm is a localized, irreversible arterial dilatation resulting from destruction of the vessel wall by infection. Pathogens causing mycotic aneurysms include Gram-positive and -negative bacteria, mycobacteria, and fungi. Klebsiella pneumoniae is a common pathogen causing urinary tract infections, nosocomial pneumonia, soft tissue infection, pyogenic liver abscesses, and endophthalmitis, while mycotic aneurysms caused by K. pneumoniae are rare. Recently, the number of cases of endogenous K. pneumoniae endophthalmitis associated with K. pneumoniae-induced pyogenic liver abscesses has increased in Southern Asia, but there have been no reports of K. pneumoniae mycotic aneurysms accompanied by endophthalmitis. Here, we report the case of a man who had a K. pneumoniae mycotic aneurysm accompanied by endophthalmitis and, ultimately, lost sight in both eyes. The early diagnosis of associated endophthalmitis requires a high index of suspicion by the physician. (Korean J Med 78:357-363, 2010)
정송이,강재훈,강세웅,Song Ee Chung,Jae Hoon Kang,Se Woong Kang 대한안과학회 2007 대한안과학회지 Vol.48 No.2
Purpose: To evaluate the clinical results of photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC). Methods: A retrospective study in a clinical practice setting of eight eyes (eight patients) with chronic CSC. The point of dye leakage on the fluorescein angiogram (FA) was too close to the fovea to treat these patients with focal laser treatment. Additionally, choroidal vascular hyperpermeability was observed with indocyanine green angiogram (ICGA). Patients were treated with verteporfin PDT and evaluated for visual acuity, complications, change in centralmacular thickness with the optical coherence tomogram (OCT), and recurrence. Results: Pre-PDT visual acuity improved from 0.46 (0.04~0.7) to 0.82 (0.15~1.2) with an average of 15.2 months follow-up post-treatment (p=0.011). The mean central macular thickness also reduced from 283 ?m to 135.5 ?m. Central macular exudation resolved completely in all eyes. There was no recurrence after PDT. Conclusions: PDT with verteporfin appeared to be a beneficial treatment option for patients with chronic CSC.
유리체황반견인을 동반한 당뇨황반부종에 대한 삼중치료의 단기 효과
백종헌,정송이,강세웅,Jong Hun Bak,Song Ee Chung,Se Woong Kang 대한안과학회 2008 대한안과학회지 Vol.49 No.12
Purpose: To evaluate the short‐term effect and safety of a triple therapy on diabetic macular edema (DME) with vitreomacular traction. Methods: Twenty‐four eyes from 24 subjects, diagnosed with DME with vitreomacular traction, were subjected to vitrectomy. Intravitreal triamcinolone acetonide injection and macular laser photocoagulation were conducted sequentially at one and 14 days after vitrectomy. Best‐corrected visual acuity (BCVA) and central macular thickness (CMT) were recorded before surgery and at three and six months after triple therapy. Results: The mean (±standard deviation [SD]) logarithm of the minimum angle of resolution BCVAs before, three, and six months after the triple therapy were 0.77±0.38, 0.48±0.27, and 0.47±0.36, respectively. The mean (±SD) CMTs before, three, and six months after the triple therapy were 407.9±127.1 µm, 272.4±104.6 µm, and 263.5±131.2 µm, respectively. The changes in BCVA at three and six months from treatment were statistically significant. Macular thickness decreased significantly at 3 and 6 months postoperatively. Conclusions: Triple therapy is a good therapeutic option for diabetic macular edema with vitreomacular traction to improve visual acuity and macular thickness.