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      • 女性性 Hormone이 甲狀腺機能에 미치는 影響에 關한 實驗的 硏究

        嚴翼富 최신의학사 1969 最新醫學 Vol.12 No.8

        This study was designed to test thyroid function of adult female rats in 26 control group of regular sex cycle, and in 48 castrated group. Thyroid responsiveness to the stimulation with female sex hormone was also evaluated in 36 castrated group, and in 12 noncastrated group with their suppressed midbrain. Sex cycle was determined by vaginal smear and the suppression of midbrain was attained by administration of chloropromazine and phenobarbital. The following parameters were tested: I131 uptake, conversion ratio of serum I131 to PBI, and histological examination of the thyroid gland. The following results were obtained 1) In the control group, I131 uptake reached its maxium value (29. 0±0. 95%) in estrus, but minimum (23.0±0.74%) in diestrus. Conversion ratio and thyroid histology showed no cyclic change. 2) In the castrated group, both I131 uptake and conversion ratio decreased from the 14th castrated day. The former continued to decrease reaching its minimum value on the 35th or 42nd day, while the latter increased from the 35th day reaching its maximum value on the 42nd or 60th day. Thyroid histology began to show hypoplastic patterns from the 14th castrated day. 3) In the castrated group, with administration of female sex hormone a. with estrogen only, 1131 uptake increased without changes in conversion ratio or thyroid histology. b. with progesterone only, no changes in three parameters c. with conbination of estrogen and progesterone, 1131 uptake and conversion ratio increased without histological changes. 4) In the non-castrated group with suppressed midbrain, estrogen only was given. I1U1 uptake decreased within the value of control group, while conversion ratio and thyroid histology were unchanged.

      • KCI등재

        혈당의 태반통과에 관한 임상적 고찰

        엄익부(IB Um) 대한산부인과학회 1965 Obstetrics & Gynecology Science Vol.8 No.11

        Estimations of blood glucose were made by Somogyi-Nelson`s method on maternal and umbilical venous blood immediately after birth in 25 cases of normal full-term pregnancy and in 18 cases of preeclampsia, which were divided into two groups; the first group (15 cases of normal pregnancy & 10 cases of preeclampsia) without dextrose injection, the second group (10 cases of normal pregnancy & 8 cases of preeclampsia with injection of 50cc of 50% D/W 10-50 min. before delivery. the baby`s blood glucose at birth was found to be lower in cases of preeclampsia than in cases of normal pregnancy. (In cases of normal preg, mother; 102.2mg. fetus;89.7mg. In cases of preeclampsia, mother;98.5mg%, fetus;75.0mg%.) This supported the view that the placenta played a governing part in fetal carbohydrate metabolism and that the transfer of glucose was somewhat impaired through the placenta in preeclampsia cases. It was also shown that free and equal transfer of glucose through the placenta was obtained in cases of normal pregnancy and in cases of preeclampsia when maternal hyperglycemia was induced. (In cases of normal pregnancy, mother;196.0mg%, fetus;165.3mg%, In cases of preeclampsia, mother;200.5mg%, fetus;171.0mg%) This can`t be explained by the present therories of the transfer of glucose. But it is suggested that in pregnancies with impaired placental function, an adequate carbohydrate diet should be ensured; and hypoglycemia in the baby can be lessened by giving glucose intravenously to the mother during labor.

      • KCI등재

        임신제 10개월에 합병된 거대 Condylomata Acuminata의 1예 보고

        최낙성(NS Choi),엄익부(IB Um),정덕기(DK Chung),박행우(JW Park),박인서(IS Park) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.8

        A 20 year old primigravida complicated with huge condylomata acuminata in the vulvar region at the 10 month of pregnancy was surgically cured by excision of tumor masses and terminated in spontaneous delivery of a male baby weighing 2.7kg and her hospital course was uneventful.

      • KCI등재

        산부인과 영역에 있어서의 Haemaccel ( 혈장증량제 ) 사용경험

        나건영(KY Na),이동경(TK Lee),임원일(WI Im),오덕겸(DK Oh),엄익부(IB Um),고근익(KI Koh) 대한산부인과학회 1965 Obstetrics & Gynecology Science Vol.8 No.9

        Thirteen gynecelogical and obstetrical patients with massive bleeding caused by various reasons were treated by infusion of "HAEMACCEL". a new plasma volume expender, manufactured by Hoechst Pharmaceutical Company in Germany. Results of the follow-up observation were as follows; 1) Patients in shock state following more than 1000cc of bleeding could be reversed to conscious state within I hour after rapid infusion of 1000 cc to 1500 cc of "HAEMACCEL". Recovery from hypotension was also coincident. 2) On Patients with less than 500cc of bleeding, safty operations were carried out without any fall in blood pressure by infusion of "HAEMCCEL" alone as a measure of replacement of the lost blood volume. 3) No overloading signs were noted with infusion of 500 to 1000 cc of "HAEMACCEL" and same amount of whole blood. 4) The value of hemoglobin was not decreased as a result of hemodilution which was expected on infusion of "HAEMACCEL". 5) Leucocytosis, which was thought caused in response to foreign body reaction, diminished sligtly in general. No significant side reactions such as fever, urticaria, bleeding tendency, etc. were noticed. 6) No sequelae of "HAEMACCEL" infusion was present.

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