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      • KCI등재

        Performance Improvement of Iterative Demodulation and Decoding for Spatially Coupling Data Transmission by Joint Sparse Graph

        ( Zhengxuan Liu ),( Guixia Kang ),( Zhongwei Si ),( Ningbo Zhang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

        Both low-density parity-check (LDPC) codes and the multiple access technique of spatially coupling data transmission (SCDT) can be expressed in bipartite graphs. To improve the performance of iterative demodulation and decoding for SCDT, a novel joint sparse graph (JSG) with SCDT and LDPC codes is constructed. Based on the JSG, an approach for iterative joint demodulation and decoding by belief propagation (BP) is presented as an exploration of the flooding schedule, and based on BP, density evolution equations are derived to analyze the performance of the iterative receiver. To accelerate the convergence speed and reduce the complexity of joint demodulation and decoding, a novel serial schedule is proposed. Numerical results show that the joint demodulation and decoding for SCDT based on JSG can significantly improve the system`s performance, while roughly half of the iterations can be saved by using the proposed serial schedule.

      • SCIESCOPUSKCI등재

        Performance Improvement of Iterative Demodulation and Decoding for Spatially Coupling Data Transmission by Joint Sparse Graph

        Liu, Zhengxuan,Kang, Guixia,Si, Zhongwei,Zhang, Ningbo Korean Society for Internet Information 2016 KSII Transactions on Internet and Information Syst Vol.10 No.12

        Both low-density parity-check (LDPC) codes and the multiple access technique of spatially coupling data transmission (SCDT) can be expressed in bipartite graphs. To improve the performance of iterative demodulation and decoding for SCDT, a novel joint sparse graph (JSG) with SCDT and LDPC codes is constructed. Based on the JSG, an approach for iterative joint demodulation and decoding by belief propagation (BP) is presented as an exploration of the flooding schedule, and based on BP, density evolution equations are derived to analyze the performance of the iterative receiver. To accelerate the convergence speed and reduce the complexity of joint demodulation and decoding, a novel serial schedule is proposed. Numerical results show that the joint demodulation and decoding for SCDT based on JSG can significantly improve the system's performance, while roughly half of the iterations can be saved by using the proposed serial schedule.

      • KCI등재

        Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets

        Zhengxuan Wang,Mingcai Liang,Bingxiao Liu,Lin Yang 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.6

        Oxidized low-density lipoprotein (ox-LDL) is an inducer of inflammation. To elucidate the link of depression of ox-LDL accumulation and anti-inflammatory function of rice protein (RP) whether dependent on methionine availability, growing and adult rats were fed RP and methionine-supplemented RP (RM) under cholesterol-enriched dietary condition. After two weeks feeding, RP and RMs exerted the anti-inflammatory effects through up-regulating IL-10, while RP and RMs significantly reduced ox-LDL levels and effectively suppressed the expressions of inflammatory mediators (COX-2, IL-1β, IL-6, TNF-α, iNOS). The anti-inflammatory molecular mechanism was to inhibit NF-κB activation and to simulate methionine sulfoxide reductase expression. Results showed, under cholesterol-enriched dietary condition, the anti-inflammatory action can be induced by RP and enhanced by methionine in growing and adult rats. The present study reveals a link of the decreased ox-LDL accumulation with the anti-inflammatory function of RP, which is dependent on methionine availability and independent of dietary cholesterol.

      • KCI등재

        L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats

        Wang Zhengxuan,Liang Mingcai,Li Hui,Liu Bingxiao,Yang Lin 한국영양학회 2022 Nutrition Research and Practice Vol.16 No.6

        BACKGROUND/OBJECTIVES 4-Hydroxy-2-nonenal (HNE) is a biomarker for oxidative stress to induce inflammation. Methionine is an essential sulfur-containing amino acid with antioxidative activity. On the other hand, the evidence on whether and how methionine can depress HNE-derived inflammation is lacking. In particular, the link between the regulation of the nuclear factor-κB (NF-κB) signaling pathway and methionine intake is unclear. This study examined the link between depression from HNE accumulation and the anti-inflammatory function of L-methionine in rats. MATERIALS/METHODS Male Wistar rats (3-week-old, weighing 70–80 g) were administered different levels of L-methionine orally at 215.0, 268.8, 322.5, and 430.0 mg/kg body weight for two weeks. The control group was fed commercial pellets. The hepatic HNE contents and the protein expression and mRNA levels of the inflammatory mediators were measured. The interleukin-10 (IL-10) and glutathione S-transferase (GST) levels were also estimated. RESULTS Compared to the control group, hepatic HNE levels were reduced significantly in all groups fed L-methionine, which were attributed to the stimulation of GST by L-methionine. With decreasing HNE levels, L-methionine inhibited the activation of NF-κB by up-regulating inhibitory κBα and depressing phosphoinositide 3 kinase/protein kinase B. The mRNA levels of the inflammatory mediators (cyclooxygenase-2, interleukin-1β, interleukin-6, inducible nitric oxide synthase, tumor necrotic factor alpha) were decreased significantly by L-methionine. In contrast, the protein expression of these inflammatory mediators was effectively down regulated by L-methionine. The anti-inflammatory action of L-methionine was also reflected by the up-regulation of IL-10. CONCLUSIONS This study revealed a link between the inhibition of HNE accumulation and the depression of inflammation in growing rats, which was attributed to L-methionine availability. The anti-inflammatory mechanism exerted by L-methionine was to inhibit NF-κB activation and to up-regulate GST.

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