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      • KCI등재후보

        Energy-efficient Low-delay TDMA Scheduling Algorithm for Industrial Wireless Mesh Networks

        ( Yun Zuo ),( Zhihao Ling ),( Luming Liu ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.10

        Time division multiple access (TDMA) is a widely used media access control (MAC) technique that can provide collision-free and reliable communications, save energy and bound the delay of packets. In TDMA, energy saving is usually achieved by switching the nodes` radio off when such nodes are not engaged. However, the frequent switching of the radio`s state not only wastes energy, but also increases end-to-end delay. To achieve high energy efficiency and low delay, as well as to further minimize the number of time slots, a multi-objective TDMA scheduling problem for industrial wireless mesh networks is presented. A hybrid algorithm that combines genetic algorithm (GA) and simulated annealing (SA) algorithm is then proposed to solve the TDMA scheduling problem effectively. A number of critical techniques are also adopted to reduce energy consumption and to shorten end-to-end delay further. Simulation results with different kinds of networks demonstrate that the proposed algorithm outperforms traditional scheduling algorithms in terms of addressing the problems of energy consumption and end-to-end delay, thus satisfying the demands of industrial wireless mesh networks.

      • β-Elemene Induces Apoptosis in Human Renal-cell Carcinoma 786-0 Cells through Inhibition of MAPK/ERK and PI3K/Akt/mTOR Signalling Pathways

        Zhan, Yun-Hong,Liu, Jing,Qu, Xiu-Juan,Hou, Ke-Zuo,Wang, Ke-Feng,Liu, Yun-Peng,Wu, Bin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

        Background: Renal-cell carcinoma (RCC) is resistant to almost all chemotherapeutics and radiation therapy. ${\beta}$-Elemene, a promising anticancer drug extracted from a traditional Chinese medicine, has been shown to be effective against various tumors. In the present study, anti-tumor effects on RCC cells and the involved mechanisms were investigated. Methods: Human RCC 786-0 cells were treated with different concentrations of ${\beta}$-elemene, and cell viability and apoptosis were measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay and flow cytometry, respectively. Protein expression was assayed by western blotting. Autophagy was evaluated by transmission electron microscopy. Results: ${\beta}$-Elemene inhibited the viability of 786-0 cells in a dose- and time-dependent manner. The anti-tumor effect was associated with induction of apoptosis. Further study showed that ${\beta}$-elemene inhibited the MAPK/ERK as well as PI3K/Akt/mTOR signalling pathways. Moreover, robust autophagy was observed in cells treated with ${\beta}$-elemene. Combined treatment of ${\beta}$-elemene with autophagy inhibitors 3-methyladenine or chlorochine significantly enhanced the anti-tumor effects. Conclusions: Our data provide first evidence that ${\beta}$-elemene can inhibit the proliferation of RCC 786-0 cells by inducing apoptosis as well as protective autophagy. The anti-tumor effect was associated with the inhibition of MAPK/ERK and PI3K/Akt/mTOR signalling pathway. Inhibition of autophagy might be a useful way to enhance the anti-tumor effect of ${\beta}$-elemene on 786-0 cells.

      • SCISCIESCOPUS

        Propofol reverses oxidative stress-attenuated glutamate transporter EAAT3 activity: Evidence of protein kinase C involvement

        Yun, J.Y.,Park, K.S.,Kim, J.H.,Do, S.H.,Zuo, Z. North-Holland 2007 European journal of pharmacology Vol.565 No.1-3

        The authors investigated the effects of propofol on EAAT3 (excitatory amino acid transporter 3) activity under oxidative stress induced by tert-butyl hydroperoxide (t-BHP), and the mediation of these effects by protein kinase C (PKC). Rat EAAT3 was expressed in Xenopus oocytes and L-glutamate (30 μM)-induced membrane currents were measured using the two-electrode voltage clamp technique. Exposure of these oocytes to t-BHP (1-20 mM) for 10 min dose-dependently decreased EAAT3 activity, and t-BHP (5 mM) significantly decreased the V<SUB>max</SUB>, but not the K<SUB>m</SUB> of EAAT3 for glutamate, and propofol (1-100 μM) dose-dependently reversed this t-BHP-attenuated EAAT3 activity. Phorbol-12-myristate-13-acetate (a PKC activator), also abolished this t-BHP-induced reduction in EAAT3 activity, whereas staurosporine (a PKC inhibitor), significantly decreased EAAT3 activity. However, as compared with staurosporine or t-BHP alone, t-BHP and staurosporine in combination did not further reduce EAAT3 activity. A similar pattern was observed for chelerythrine (also a PKC inhibitor). In oocytes pretreated with combinations of t-BHP and PMA (or staurosporine), propofol failed to change EAAT3 activity. Our results suggest that propofol restores oxidative stress-reduced EAAT3 activity and that these effects of propofol may be PKC-mediated.

      • KCI등재

        One-Pot Preparation of Graphene-Based Polyaniline Conductive Nanocomposites for Anticorrosion Coatings

        Yun Zhao,Jiangquan Ma,Kun Chen,Chuandong Zhang,Chao Yao,Shixiang Zuo,Yong Kong 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.5

        Graphene-based polyaniline (PANI/RGO), used as conductive filler, was synthesized through a new one-pot emulsion polymerization technology. Graphene dispersion (RGO) was obtained by ultrasonically reducing graphene oxide (GO) in a hot sodium hydroxide solution in the absence of any toxic reductant, such as hydrazine hydrate. Sodium dodecyl benzene sulfonate (SDBS), in which RGO sheets were dispersed, was synthesized using dodecyl benzenesulfonic acid (DBSA) and NaOH. In this RGO/SDBS mixture, polyaniline (PANI), doped with multiple acids (HClDBSA), was then uniformly polymerized on the surface of the RGO sheets. The experimental results showed that this reaction improved the dispersion of the RGO in the PANI system, and increased the homogeneous distribution of the formed PANI particles on the RGO surface. The synthesized composite material (PANI/RGO) had good thermal stability, electrical conductivity (about 11.71 S · cm -1) and water dispersibility. Based on its excellent properties, the PANI/RGO was combined with waterborne epoxy resin to prepare anticorrosion coatings. The corrosion resistance of these coatings was studied using Tafel plots, along with other critical properties tested by the national standards. The results suggested that the surface resistivity of the coatings could be as high as 2.48 X 10 8 Ω with the addition around 3 wt.% of the PANI/RGO meeting good antistatic standards. In addition, the antistatic coatings had outstanding corrosion resistance, as well as tremendous physical and chemical properties.

      • Transferred inter-cell ischemic preconditioning-induced neuroprotection may be mediated by adenosine A1 receptors

        Yun, Jungyeon,Li, Jun,Zuo, Zhiyi Elsevier 2014 Brain research bulletin Vol.103 No.-

        <P>Ischemic preconditioning-induced neuroprotection is a well-known phenomenon. We hypothesize that this form of neuroprotection is transferable among the same type of cells. To test this hypothesis, human neuroblastoma SH-SY5Y cells were induced to become neuron-like cells. Primary rat cortical neuronal cultures were also used. These cells were subjected to various lengths of short oxygen-glucose deprivation (OGD, an in vitro simulation of ischemia) and then 1-h OGD. Some cells that were not exposed to a short episode of ischemia were incubated with culture medium from the cells that had 3- or 5-min OGD. Those cells were subjected to OGD for 1h at 1 or 24h after they were exposed to the medium. Cell injury was evaluated at 24h after the 1-h OGD by lactate dehydrogenase release assay. In another experiment, cells subjected to a 3-min OGD or exposed to the medium from cells that had a 3-min OGD were harvested at 30min after the OGD or the medium exposure for Western blotting of Akt, a prosurvival protein. Our study showed that a prior episode of ischemia lasting from 3 to 10min significantly reduced the 1-h OGD-induced cell injury. Medium from cells subjected to a 3-min OGD also induced acute and delayed phases of neuroprotection in OGD-na?ve human neuron-like cells and primary rat cortical neuronal cultures. Cells subjected to a 3-min OGD or incubated with the medium from cells exposed to a 3-min OGD had increased phosphorylated/activated Akt. The increased phosphorylated Akt and neuroprotection induced by medium transferring were inhibited by 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), an adenosine A1 receptor inhibitor. The 3-min OGD-induced neuroprotection was inhibited by LY294002, an Akt activation inhibitor. These results suggest that ischemic preconditioning-induced neuroprotection is transferable among the cells. Small molecules, such as adenosine, may mediate this effect.</P>

      • Photoactivation and inactivation of <i>Arabidopsis</i> cryptochrome 2

        Wang, Qin,Zuo, Zecheng,Wang, Xu,Gu, Lianfeng,Yoshizumi, Takeshi,Yang, Zhaohe,Yang, Liang,Liu, Qing,Liu, Wei,Han, Yun-Jeong,Kim, Jeong-Il,Liu, Bin,Wohlschlegel, James A.,Matsui, Minami,Oka, Yoshito,Lin American Association for the Advancement of Scienc 2016 Science Vol.354 No.6310

        <P>Cryptochromes are blue-light receptors that regulate development and the circadian clock in plants and animals. We found that Arabidopsis cryptochrome 2 (CRY2) undergoes blue light-dependent homodimerization to become physiologically active. We identified BIC1 (blue-light inhibitor of cryptochromes 1) as an inhibitor of plant cryptochromes that binds to CRY2 to suppress the blue light-dependent dimerization, photobody formation, phosphorylation, degradation, and physiological activities of CRY2. We hypothesize that regulated dimerization governs homeostasis of the active cryptochromes in plants and other evolutionary lineages.</P>

      • KCI등재후보

        Low-delay Node-disjoint Multi-path Routing using Complementary Trees for Industrial Wireless Sensor Networks

        ( Luming Liu ),( Zhihao Ling ),( Yun Zuo ) 한국인터넷정보학회 2011 KSII Transactions on Internet and Information Syst Vol.5 No.11

        Complementary trees are two spanning trees rooted at the sink node satisfying that any source node`s two paths to the sink node on the two trees are node-disjoint. Complementary trees routing strategy is a special node-disjoint multi-path routing approach. Several complementary trees routing algorithms have been proposed, in which path discovery methods based on depth first search (DFS) or Dijkstra`s algorithm are used to find a path for augmentation in each round of path augmentation step. In this paper, a novel path discovery method based on multi-tree-growing (MTG) is presented for the first time to our knowledge. Based on this path discovery method, a complementary trees routing algorithm is developed with objectives of low average path length on both spanning trees and low complexity. Measures are employed in our complementary trees routing algorithm to add a path with nodes near to the sink node in each round of path augmentation step. The simulation results demonstrate that our complementary trees routing algorithm can achieve low average path length on both spanning trees with low running time, suitable for wireless sensor networks in industrial scenarios.

      • KCI등재

        De novo assembly and characterization of antennal transcriptome reveal chemosensory system in Nysius ericae

        Ya-Nan Zhang,Xiu-Yun Zhu,Qian Zhang,Cai-Yun Yin,Zhi-PingDong,Ling-Hua Zuo,Dao-Gui Deng,Liang Sun,Xiao-Ming Li 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.4

        Chemosensory system plays important roles in insect behaviors, some key genes governing chemosensation can potentially be used as novel targets for pest control. Nysius ericae (Hemiptera: Lygaeidae) is a polyphagous insect pest found throughout Eurasia countries which causes damage to many important crops. Little is known about the chemosensory mechanisms of host location and mate choice in N. ericae at themolecular level. Here, we assembled the antennal transcriptome of N. ericae using Illumina sequencing technology. Analysis of the transcriptome data identified 148 candidate chemosensory genes, including 28 for odorant binding proteins (OBPs), 16 for chemosensory proteins (CSPs), 2 for sensory neuron membrane proteins (SNMPs), 83 odorant receptors (ORs), 12 ionotropic receptors (IRs), and 7 gustatory receptors (GRs). Our results greatly improve the gene inventory for N. ericae and provide valuable resources for analyzing the functions of some key genes. This information will aid in the development of better understanding of chemosensation in N. ericae, and indicate novel targets for managing its impact on agriculture. Chemosensory system plays important roles in insect behaviors, some key genes governing chemosensation can potentially be used as novel targets for pest control. Nysius ericae (Hemiptera: Lygaeidae) is a polyphagous insect pest found throughout Eurasia countries which causes damage to many important crops. Little is known about the chemosensory mechanisms of host location and mate choice in N. ericae at themolecular level. Here, we assembled the antennal transcriptome of N. ericae using Illumina sequencing technology. Analysis of the transcriptome data identified 148 candidate chemosensory genes, including 28 for odorant binding proteins (OBPs), 16 for chemosensory proteins (CSPs), 2 for sensory neuron membrane proteins (SNMPs), 83 odorant receptors (ORs), 12 ionotropic receptors (IRs), and 7 gustatory receptors (GRs). Our results greatly improve the gene inventory for N. ericae and provide valuable resources for analyzing the functions of some key genes. This information will aid in the development of better understanding of chemosensation in N. ericae, and indicate novel targets for managing its impact on agriculture.Chemosensory system plays important roles in insect behaviors, some key genes governing chemosensation can potentially be used as novel targets for pest control. Nysius ericae (Hemiptera: Lygaeidae) is a polyphagous insect pest found throughout Eurasia countries which causes damage to many important crops. Little is known about the chemosensory mechanisms of host location and mate choice in N. ericae at themolecular level. Here, we assembled the antennal transcriptome of N. ericae using Illumina sequencing technology. Analysis of the transcriptome data identified 148 candidate chemosensory genes, including 28 for odorant binding proteins (OBPs), 16 for chemosensory proteins (CSPs), 2 for sensory neuron membrane proteins (SNMPs), 83 odorant receptors (ORs), 12 ionotropic receptors (IRs), and 7 gustatory receptors (GRs). Our results greatly improve the gene inventory for N. ericae and provide valuable resources for analyzing the functions of some key genes. This information will aid in the development of better understanding of chemosensation in N. ericae, and indicate novel targets for managing its impact on agriculture.

      • KCI등재후보

        The Influence of Enjoyment Factors, Satisfaction, and Flow Experience on the Happiness of Chinese Dance Sports Participants

        Yongdi Wang,Ling Chen,Yun Liu,Junke Wang,Wang Zuo 아시아스포츠융합과학회 2023 Asia Pacific Journal of Applied Sport Sciences Vol.4 No.2

        PPURPOSE This research investigates the current experience and satisfaction of Chinese university students participating in dance sports by investigating the participation and enjoyment factors. We provide a theoretical basis for the further development of Chinese dance sports. METHODS In this study, the research hypothesis is discussed and the structural equation model (SEM) is established. The research assumes that engagement factors, satisfactions, and flow experience can have an impact on happiness, and Amos 26.0 is used for data analysis. A total of 400 valid questionnaires were recovered. RESULTS The factor loading of the SEM falls between 0.469 and 0.911, and the model fits well. The path coefficient reached a significant level, and flow experience had an impact on happiness, thereby supporting the hypothesis. CONCLUSION The results show that enjoyment factors, satisfaction, and flow experience have a positive effect on happiness, and enjoyment factors have a positive impact on university students’ satisfaction and flow experience.

      • KCI등재

        Simulation analysis and evaluation of decontamination effect of different abrasive jet process parameters on radioactively contaminated metal

        Zhong Lin,Deng Jian,Zuo Zhe-wen,Huang Can-yu,Chen Bo,Lei Lin,Lei Ze-yong,Lei Jie-heng,Zhao Mu,Hua Yun-fei 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.11

        A new method of numerical simulating prediction and decontamination effect evaluation for abrasive jet decontamination to radioactively contaminated metal is proposed. Based on the Computational Fluid Dynamics and Discrete Element Model (CFD-DEM) coupled simulation model, the motion patterns and distribution of abrasives can be predicted, and the decontamination effect can be evaluated by image processing and recognition technology. The impact of three key parameters (impact distance, inlet pressure, abrasive mass flow rate) on the decontamination effect is revealed. Moreover, here are experiments of reliability verification to decontamination effect and numerical simulation methods that has been conducted. The results show that: 60Co and other homogeneous solid solution radioactive pollutants can be removed by abrasive jet, and the average removal rate of Co exceeds 80%. It is reliable for the proposed numerical simulation and evaluation method because of the well goodness of fit between predicted value and actual values: The predicted values and actual values of the abrasive distribution diameter are Ф57 and Ф55; the total coverage rate is 26.42% and 23.50%; the average impact velocity is 81.73 m/s and 78.00 m/s. Further analysis shows that the impact distance has a significant impact on the distribution of abrasive particles on the target surface, the coverage rate of the core area increases at first, and then decreases with the increase of the impact distance of the nozzle, which reach a maximum of 14.44% at 300 mm. It is recommended to set the impact distance around 300 mm, because at this time the core area coverage of the abrasive is the largest and the impact velocity is stable at the highest speed of 81.94 m/s. The impact of the nozzle inlet pressure on the decontamination effect mainly affects the impact kinetic energy of the abrasive and has little impact on the distribution. The greater the inlet pressure, the greater the impact kinetic energy, and the stronger the decontamination ability of the abrasive. But in return, the energy consumption is higher, too. For the decontamination of radioactively contaminated metals, it is recommended to set the inlet pressure of the nozzle at around 0.6 MPa. Because most of the Co elements can be removed under this pressure. Increasing the mass and flow of abrasives appropriately can enhance the decontamination effectiveness. The total mass of abrasives per unit decontamination area is suggested to be 50 g because the core area coverage rate of the abrasive is relatively large under this condition; and the nozzle wear extent is acceptable

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