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Rational thinking on China`s economic circle
( Qi Ping Ren ),( Yan Zhao Gong ) 한국세무회계학회 2007 발표논문집 Vol.21 No.-
Chinas economic development a variety of economic circles have been form dorenvisaged and up to date the number of them has already reached 42 of them most famous are the three economic circles, In addition there are alse economic circles coastal city economic circle and the second-grade urban economic circles. under the large metropolitan area. Administrative institution segment is one of the most serious obstacles to regional economic development this happens not only in industry with high price and high profits, but also in infrastructures such as port airdrome, economic circles in china are composed of cities with different grades, different administrators and different functions although there are still various problems with the development of economic circles in china the development prospects are promising if essential action.
Qi, Guojia,Yuan, Ping,Qi, Miao,Hu, Xiuli,Shi, Shangpeng,Shi, Xiuquan Occupational Safety and Health Research Institute 2022 Safety and health at work Vol.13 No.3
Background: PTSD (Post-traumatic stress disorder, PTSD) had a great impact on health care workers during the COVID-19 (Corona Virus Disease 2019, COVID-19). Better knowledge of the prevalence of PTSD and its risk factors is a major public health problem. This study was conducted to assess the prevalence and important risk factors of PTSD among medical staff during the COVID-19. Methods: The databases were searched for studies published during the COVID-19, and a PRISMA (preferred reporting items for systematic review and meta-analysis) compliant systematic review (PROSPERO-CRD 42021278970) was carried out to identify articles from multiple databases reporting the prevalence of PTSD outcomes among medical staff. Proportion random effect analysis, I<sup>2</sup> statistic, quality assessment, subgroup analysis, and sensitivity analysis were carried out. Results: A total of 28 cross-sectional studies and the PTSD results of doctors and nurses were summarized from 14 and 27 studies: the prevalences were 31% (95% CI [confidence interval, CI]: 21%-40%) and 38% (95% CI: 30%-45%) in doctors and nurses, respectively. The results also showed seven risks (p < 0.05): long working hours, isolation wards, COVID-19 symptoms, nurses, women, fear of infection, and pre-existing mental illness. Two factors were of borderline significance: higher professional titles and married. Conclusion: Health care workers have a higher prevalence of PTSD during COVID-19. Health departments should provide targeted preventive measures for medical staff away from PTSD.
Tang, Qi-Ling,Guo, Ji-Quan,Wang, Qi-You,Lin, Hai-Shu,Yang, Zhou-Ping,Peng, Tong,Pan, Xue-Diao,Liu, Bing,Wang, Su-Jun,Zang, Lin-Quan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6
Curcumol is a sesquiterpene originally isolated from curcuma rhizomes, a component of herbal remedies commonly used in oriental medicine. Its beneficial pharmacological activities have attract significant interest recently. In this study, anti-cancer activity of curcumol was examined with both in vitro and in vivo models. It was found that curcumol exhibited time- and concentration-dependent anti-proliferative effects in SPC-A-1 human lung adenocarcinoma cells with cell cycle arrest in the G0/G1 phase while apoptosis-induction was also confirmed with flow cytometry and morphological analyses. Interestingly, curcumol did not display growth inhibition in MRC-5 human embryonic lung fibroblasts, suggesting the anti-proliferative effects of curcumol were specific to cancer cells. Anti-neoplastic effects of curcumol were also confirmed in tumor bearing mice. Curcumol (60 mg/ kg daily) significantly reduced tumor size without causing notable toxicity. In conclusion, curcumol appears a favorable anti-cancer candidate for further development.
3GPP LTE 액세스 시스템 검증을 위한 단말 시뮬레이터 설계
양치평 ( Qi-ping Yang ),차원수 ( Won-soo Cha ),김재우 ( Jae-woo Kim ),김태형 ( Tae-hyong Kim ) 한국정보처리학회 2008 한국정보처리학회 학술대회논문집 Vol.15 No.2
본 논문은 시스템의 안정성과 검증성, 설계 및 관리 용이성을 위해 SDL 언어 및 Pure-SDL 설계 접근기법을 이용하여 3GPP LTE 액세스 시스템 검증을 위한 단말 시뮬레이터를 설계 및 구현하였다. 설계된 시스템은 관리 효율성을 위해 블록 타입 및 공통 패키지 설계를 통한 다중 시스템 구조를 갖는다. 구현된 단말 시뮬레이터는 실제 3GPP LTE 액세스 시스템 검증에서 우수한 안정성을 보여주었다.
Enzymatic Synthesis of Theanine with L-glutamine-Zn(II) Complexes
Hao-Qi Wang,Zhong Yao,Zhi Zhou,Yun Sun,Ping Wei,Ping-Kai Ouyang 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.6
Theanine, a unique amino acid found in tea plants, has many important physiological functions. Theanine can be enzymatically synthesized via the γ-glutamyltranspeptidation reaction. In this study, we described a new method of theanine synthesis using the L-glutamine-Zn(II)(Zn(Gln)2) complex instead of glutamine as the donor,which successfully reduced the side autotranspeptidation reaction and led to higher yield of theanine. We prepared the Zn(Gln)2 complexes and showed that they are stable in liquid bulk under 9.0 pH. After using the Zn(Gln)2 in the γ-glutamyltranspeptidation reaction, we utilized HPLC and Mass spectrometry analysis to demonstrated that Zn(Gln)2was an more effective γ-glutamyl donor than glutamine. The autotranspeptidation reaction was restrained effectively. As a result, the theanine yield and the conversion rate for glutamine were vastly improved. In a reaction mixture containing 48 mM of Zn(Gln)2, 1.6 M ethylamine, and 0.5 U/mL GGT, the final concentration of theanine obtained was 61.3 mM after incubation at 37oC for three hours. The conversion rate for glutamine was 63.8%, which showed a 16.9% increase as compared to when using glutamine alone as the donor substrate.
은기평(YIN Qi-ping),진주파(CHEN Shu-bo) 부경대학교 인문사회과학연구소 2006 인문사회과학연구 Vol.6 No.-
"The road of literature" has recently become a pejorative term. Behind such a phenomenon lurks a prevalent assumption: that English education is a matter of ingesting information, of mastering technique, of acquiring facts and know-how, whereas literature is a soft option, an indulgence or a mere trimming to decorate the hard center of the market-oriented syllabus. In order to counter such a trend, we need first of all to address the following theoretical issues: What is the primary task of an English department in China? Is the teaching of English literature relevant to the Chinese market economy today? If yes, in what way is it relevant? How does one persuade a member of modern Chinese society that there is a profit in reading, say, Chaucer and Shakespeare in harkening to any non-Chinese and, "worse", non-modern non-Chinese voices? While re-examining those questions, we need to improve some of our teaching methods that are still prevalent today, in order to make sure that literature is given its due status in English teaching programmes.
Liu, Xiao-Qi,Jiang, Rong,Li, Si-Qi,Wang, Jing,Yi, Fa-Ping Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Prostate cancer is the most common cancer in men. In this study, we investigated immune responses of cytotoxic T lymphocytes (CTLs) against TRAMP-C2 prostate cancer cells after activation by dendritic cells (DCs) loaded with TRAMP-C2 freeze-thaw antigen and/or PEP-3 peptide in vitro. Bone marrow-derived DC from the bone marrow of the C57BL/6 were induced to mature by using the cytokine of rhGM-CSF and rhIL-4, and loaded with either the freeze-thaw antigen or PEP-3 peptide or both of them. Maturation of DCs was detected by flow cytometry. The killing efficiency of the CTLs on TRAMP-C2 cells were detected by flow cytometry, CCK8, colony formation, transwell migration, and wound-healing assay. The levels of the IFN-${\gamma}$, TNF-${\beta}$ and IL-12 were measured by enzyme-linked immunosorbent assay (ELISA). Compared with the unloaded DCs, the loaded DCs had significantly increased expression of several phenotypes related to DC maturation. CTLs activated by DCs loaded with freeze-thaw antigen and PEP-3 peptide had more evident cytotoxicity against TRAMP-C2 cells in vitro. The secretion levels of IFN-${\gamma}$, TNF-${\beta}$ and IL-12, secreted by DCs loaded with antigen and PEP-3 and interaction with T cells, were higher than in the other groups. Our results suggest that the CTLs activated by DCs loaded with TRAMP-C2 freeze-thaw antigen and PEP-3 peptide exert a remarkable killing efficiency against TRAMP-C2 cells in vitro.
Huang, Yue-Han,Chen, Zhen-Kun,Huang, Ka-Te,Li, Peng,He, Bin,Guo, Xu,Zhong, Jun-Qiao,Zhang, Qi-Yu,Shi, Hong-Qi,Song, Qi-Tong,Yu, Zheng-Ping,Shan, Yun-Feng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Aim: To study any correlation of LKB1 expression with prognosis in hepatocellular carcinoma (HCC) cases. Methods: A total of 70 HCC patients and 20 primary intrahepatic stone patients in the first affiliated hospital of Wenzhou Medical College were enrolled in this study. LKB1 expression was detected by immunohistochemistry. Patients were followed-up and prognostic factors were evaluated. Result: LKB1 expression was decreased in the HCC samples. Loss of LKB1 expression in HCC was significantly related to histologic grade (P=0.010), vascular invasion (P=0.025) and TMN stage (P=0.011). Patients showing negative LKB1 expression had a significantly shorter disease-free and overall survival than those with positive expression (P = 0.001, P=0.000, respectively). Multivariate Cox regression analysis indicated that LKB1 expression level was an independent factor of survival (P = 0.033). Conclusion: HCC patients with decreased expression LKB1 have a poor prognosis. The loss of LKB1 expression is correlated with a lower survival rate.