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( Keiichi Takaya ) 경북대학교 중등교육연구소 2018 Asia Pacific Journal of Educational Research Vol.1 No.1
Caroline Pratt opened her Play School in New York’s Greenwich Village in 1914 with its unique curriculum featuring such unconventional activities as block building and field trips. The school continues to this day with its original principles and activities kept largely intact and has been highly regarded by many parents and educators; but it is also criticized for valuing child-centeredness at the expense of planning and structure. I will argue, however, that the school has a definite curriculum, and that the crucial part of it, the way Pratt conceptualized play as a means to assist children’s cognitive as well as social and emotional development, goes beyond the scope of child-centered education.
Nozawa, Takaya,Yoon, Sung-Chul,Maeda, Keiichi,Kozasa, Takashi,Nomoto, Ken'ichi,Langer, Norbert University of Chicago Press for the American Astro 2014 ASTROPHYSICAL JOURNAL LETTERS - Vol.787 No.2
We investigate the formation of dust in a stellar wind during the red-supergiant (RSG) phase of a very massive Population III star with a zero-age main sequence mass of 500 M-circle dot. We show that, in a carbon-rich wind with a constant velocity, carbon grains can form with a lognormal-like size distribution, and that all of the carbon available for dust formation finally condenses into dust for wide ranges of the mass-loss rate ((0.1-3) x 10(-3) M-circle dot yr(-1)) and wind velocity (1-100 km s(-1)). We also find that the acceleration of the wind, driven by newly formed dust, suppresses the grain growth but still allows more than half of the gas-phase carbon to finally be locked up in dust grains. These results indicate that, at most, 1.7 M-circle dot of carbon grains can form during the RSG phase of 500 M-circle dot Population III stars. Such a high dust yield could place very massive primordial stars as important sources of dust at the very early epoch of the universe if the initial mass function of Population III stars was top-heavy. We also briefly discuss a new formation scenario of carbon-rich ultra-metal-poor stars, considering feedback from very massive Population III stars.
Yoshihiko Ogawa,Masatoshi Sato,Takaya Yamashita,Ryuichi Nakano,Satoshi Mochizuki,Kei Kasahara,Hisakazu Yano,Keiichi Mikasa 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.1
Dear Editor, Intraabdominal infections are well-known sources of polymicrobial bacteremia [1, 2]. Anaerobes such as Bacteroides spp. and Clostridium spp. account for 30–50% of these cases [2-4]. However, a significant proportion of anaerobes remain unidentified. Lee et al [5] reported that the conventional identification method correctly identifies anaerobic bacteria only 79.4% to the genus level and 60.1% to the species level. Here, we report a case of polymicrobial bacteremia with three anaerobes in a patient with peritonitis following intestinal perforation. The anaerobes included Butyricimonas virosa and Brachyspira pilosicoli, both of which are difficult to identify by the conventional identification method
Hyperfractionated radiotherapy for re-irradiation of recurrent esophageal cancer
Kazuya Takeda,Haruo Matsushita,Rei Umezawa,Takaya Yamamoto,Yojiro Ishikawa,Noriyoshi Takahashi,Yu Suzuki,Keiichi Jingu 대한방사선종양학회 2021 Radiation Oncology Journal Vol.39 No.4
Purpose: Re-irradiation is a treatment option for recurrent esophageal cancer patients with a history of radiotherapy, but there is a risk of severe late adverse effects. This study focused on the efficacy and safety of re-irradiation using hyperfractionated radiotherapy. Materials and Methods: Twenty-six patients who underwent re-irradiation by the hyperfraction technique using twice-daily irradiation of 1.2 Gy per fraction for recurrent esophageal cancer were retrospectively included in this study. The overall survival period after the start of secondary radiotherapy and the occurrence of late adverse effects were investigated. Results: Of 26 patients, 21 (81%) received re-irradiation with definitive intention and 21 (81%) underwent concurrent chemotherapy. The median re-irradiation dose was 60 Gy in 50 fractions in 25 treatment days, and the median accumulated irradiation dose in equivalent dose in 2 Gy per fraction was 85.4 Gy with an α/β value of 3. The median interval between two courses of radiotherapy was 21.0 months. The median overall survival period was 15.8 months and the 1-year and 3-year overall survival rates were 64.3% and 28.3%, respectively. Higher dose of re-irradiation and concurrent chemotherapy significantly improved survival (p < 0.001 and p = 0.019, respectively). Severe late adverse effects with the Common Terminology Criteria for Adverse Events grade 3 or higher were observed in 5 (19.2%) patients, and 2 (7.7%) of them developed a grade 5 late adverse effect. Conclusion: High-dose re-irradiation using a hyperfractionated schedule with concurrent chemotherapy might be related to good prognosis, while the rate of late severe adverse effects is not high compared with the rates in past reports.