http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Katsuya Endo ) (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
( Rintaro Moroi ),( Katsuya Endo ),( Katsutoshi Yamamoto ),( Takeo Naito ),( Motoyuki Onodera ),( Masatake Kuroha ),( Yoshitake Kanazawa ),( Tomoya Kimura ),( Yoichi Kakuta ),( Atsushi Masamune ),( Yo 대한장연구학회 2019 Intestinal Research Vol.17 No.1
Background/Aims: Few reports have described the long-term treatment outcomes of the anti-tumor necrosis factor-α anti body for Japanese Crohn’s disease (CD) patients. The aim of this study was to evaluate them and clarify the clinical factors that affect the long-term prognosis of the anti-tumor necrosis factor-α treatments. Methods: This was a retrospective, observational, single-center cohort study. Japanese CD patients treated with either infliximab or adalimumab as a first-line therapy were ana lyzed. The cumulative retention rates of the biologics, relapse-free survival, and surgery-free survival were analyzed using Ka plan-Meier methods. The clinical factors associated with the long-term outcomes were estimated by both the log-rank test and Cox proportional hazard model. Results: The cumulative retention rate was significantly higher in the group with a concomi tant elemental diet of ≥900 kcal/day, baseline C-reactive protein (CRP) levels <2.6 mg/dL, and baseline serum albumin levels ≥3.5 g/dL, respectively. The baseline serum albumin levels were also associated with both relapse-free and surgery-free survival. The lack of concomitant use of an elemental diet ≥900 kcal/day was identified as the only independent risk factor for the with drawal of the biologics. Conclusions: Baseline CRP levels and serum albumin levels could affect the long-term outcomes in CD patients. Concomitant elemental diet of ≥900 kcal/day could have a positive influence on clinical treatment course. (Intest Res 2019;17:94-106)
-
Environmentally Friendly Fabrication of Functional Nanocrystals on Surface-Modified Carbon Nanotubes
SunHyung Lee,Katsuya Teshima,Morinobu Endo,Shuji Oishi 한국표면공학회 2010 한국표면공학회 학술발표회 초록집 Vol.2010 No.11
The functionalization process of carbon nanotubes (CNTs) is required as a primary step in fabricating CNTs-supported composites. In this study, CNTs were treated using vacuum ultraviolet (VUV) in order to functionalize their sidewalls with functional groups. The functional groups were used as reaction sites of the various functional nanocrystals, such as platinum and nickel. Additionally, the functional nanocrystals/carbon nanotube composites were successfully fabricated using various synthesis methods. There were investigated that the composites applied to the catalyst in fuel cells and cathode material.
-
( Eiki Nomura ),( Yoshitaka Kinouchi ),( Tooru Shimosegawa ),( Sho Takagi ),( Hisashi Shiga ),( Nobuya Obana ),( Katsuya Endo ),( Nobuo Ueki ),( Kenichi Negoro ),( Seichi Takahashi ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Cronkhite-Canada syndrome (CCS) is a rare nonhereditary disorder with gastrointestinal (GI) polyposis, associated with ectodermal changes. GI polyps are generally accepted to be nonneoplastic in nature. However, GI malignancy have been described in some CCS patients. Methods: Two cases of CCS associated with GI cancer and membranous glomerulonephritis (MGN) were examined about clinicopathological features. Results: 〔Case 1〕 A 71-year-old man had GI polyposis. The skin of his legs showed brown pigmentation and his fingernails and toenails were atrophic. He had proteinuria and the biopsied specimen of the kidney revealed MGN. We made a diagnosis of CCS associated with MGN. Treatment with methylprednisolone and cyclosporine ameliorated the symptoms and the GI polyposis Colonoscopy after the treatment showed the regression of the polyposis and the histological examination of the remnant polyp after endoscopic resection showed well differentiated adenocarcinoma. Twelve months after the resection, he achieved remission and no recurrence of the polyposis was found. 〔Case 2〕 A 58-year-old man was admitted our hospital for the examination of the progression of anemia. HE was diagnosed as MGN at 24 years old and was under medical treatment. He had poor nutrition, with the typical clinical features of CCS. He had also taste disturbance. Radiologic, endoseopic and histological examinations confirmed CCS polyposis in the stomach, small intestine and colon. He was treated with prednisolone, oral zinc and tranexamic acid and was improved of the symptoms. Six months after the diagnosis, follow-up upper GI scopy showed no change of the diffuse polyposis of the stomach, whereas the histological findings of the biopsied specimens from the lower body polyp revealed to be an adenocarcinoma. He was performed a total gastrectomy. Conclusions: Although the frequency of malignant transformation is considered to be low in CCS, it has definite malignant potential and a close follow-up examination is recommended.
-
Basic Verification of β-D Glucan in Leukocyte-Rich Plasma for the Diagnosis of Deep Mycosis
Shimoyama Ken,Kan Shigenori,Takahashi Gaku,Morino Gota,Yamada Yasuhiko,Inoue Yoshihiro,Inada Katsuya,Endo Shigeatsu 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.1
Background: Currently, supplementary serological testing for β-D glucan (BDG) is often selected to diagnose deep mycosis in care covered by the health insurance in Japan. The Wako method used by our center has low sensitivity, and different studies have used different cut-off values due to factors that cause false positives and false negatives. One possible cause of false negatives is the use of platelet-rich plasma (PRP) as the sample material. Because phagocytic white blood cells (WBC) are precipitated by centrifugation and only plasma is measured, it seems unlikely that the actual amount of BDG is being measured when using PRP. Further, a frequent cause of false positives is contamination from blood products and gauze containing BDG. To resolve these issues, the blood cell separator, hydroxyethyl starch, is used to precipitate only the red blood cells to obtain leukocyte-rich plasma (LRP). We hypothesized that it might be possible to improve the diagnostic rate of deep mycosis by measuring the BDG content of plasma containing WBC and fungal components and by comparing the BDG content of PRP and LRP measured simultaneously. Materials and Methods: Healthy human blood, albumin-added blood, wrung-out gauze fluid-added blood, and fungal solution-added blood were prepared, and PRP and LRP were prepared using hydroxyethyl starch. The BDG content of each sample was measured using the Wako method and compared. In addition, PRP and LRP of fungal-added blood were Gramstained and examined under a microscope, and the number of WBCs and phagocytosed fungi was counted visually and compared. Results: Measuring the BDG content of LRP confirmed that there were no false positives with LRP, and in vitro experiments comparing albumin-added false-positive blood to fungal-added blood showed significant differences between PRP and LRP only in the fungal-added blood. Conclusion: Calculating the BDG-ratio (LRP/PRP) by measuring both LRP and PRP may eliminate false positives and false negatives of true deep mycosis and improve the diagnostic rate.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
