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      • Tracheobronchopathia Osteochlastica: A Study of 22 Patients from Serbia

        ( Jovan Javorac ),( Dejan Zivanovic ),( Miroslav Ilic ),( Ivan Kopitovic ),( Ana Milenkovic ),( Nevena Savic ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

        Background Tracheobronchopathia osteochalstica (TO) is an indolent and rare airway disorder with a favourable prognosis, characterized by the presence of submucosal cartilage or bone nodules in the wall of the laryngotracheobronchial tree, that can lead to its narrowing. The aim of this study was to determine the frequency of this disorder in the general population, as well as to obtain basic socio-demographic characteristics of patients and the clinical manifestations of TO. Methods Endoscopic findings of patients who underwent bronchoscopy at the Institute for Pulmonary Diseases of Vojvodina, Serbia from 01.01.2013 to 01.01.2021 were analyzed. For patients in whom the existence of TO was confirmed, individual sociodemographic data were collected and clinical parameters were analyzed. Results Analysis of 14.545 bronchoscopic findings showed that TO was presented in 22 patients (0.15%). Our sample consisted of predominantly males (68.2%), while the mean age was 70.12. Approximately one-third of patients (32%) had a previously established respiratory disease (COPD and asthma most usually). In most cases, TO was found as an accidental finding during bronchoscopy indicated for other reasons (lung carcinoma in 50% of cases, inflammatory diseases of lung in 32%, other reasons in 18%). The trachea (especially its lower two-thirds) was the most common site of TO (73% of patients). The most common pre-bronchoscopic symptoms were cough, shortness of breath and chest pain. No significant narrowing of the laryngotracheobronchial lumen was found in any of the patients. Thus, none of them was treated with specific therapy for TO but received only symptomatic therapy and therapy aimed at the underlying respiratory disease. Conclusion Tracheobronchopathia osteochlastica is a rare and usually an underdiagnosed disorder. Its recognition can be important in everyday clinical practice, due to significant respiratory symptoms and impaired quality of life in patients with TO, as well as potential difficulties during endotracheal intubation.

      • The COVID-19 Pandemic - Related Burnout and Distress among Healthcare Professionals Treating Patients with Respiratory Diseases in Serbia

        ( Dejan Zivanovic ),( Jovan Javorac ),( Jelena Blanusa ),( Svetlana Stojkov ),( Jasmina Knezevic ),( Ivan Kopitovic ),( Miroslav Ilic ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

        Background The COVID-19 pandemic put enormous pressure on healthcare systems and health workers around the world. With this study, we aimed to investigate the presence of burnout during the COVID-19 pandemic among healthcare professionals treating patients with respiratory diseases. Methods This research was conducted during the first wave of the COVID-19 pandemic in the Republic of Serbia, from April 23rd to May 8th 2020, among healthcare professionals from several facilities that treat pulmonary patients. The respondents were asked to complete a web-based questionnaire that included Copenhagen Burnout Inventory (CBI) and Four-Dimensional Symptom Questionnaire (4DSQ). Basic socio-demographic parameters were collected as well. Results This study included 44 respondents. Among them, 26 (59%) were physicians, while 18 (41%) were nurses. Females were predominantly represented in our sample (70.5%). The mean age of respondents was 40.2, ranging from 21 to 64 years. The average lenght of service in the healthcare system was 14.7 years. Only 8 of our respondents (18.2%) have not dealt with COVID-19 patients in their clinical work, while 22 (50%) were treating COVID-19 patients on a daily basis. The mean score of our respondents achieved on CBI was 51.08 (SD, 24.12). A low level of burnout experienced 20 (45.5%) of healthcare professionals, moderate 15 (34%), while a high level of burnout was presented in 9 (20.5%) of respondents. The mean value of the distress scale from 4DSQ was 21.02 (SD, 9.6), with 18 of respondents (41%) experiencing a low level of distress, 16 (36.4%) moderate, while 10 (22.6%) manifested a high level of distress. These Results are presented in Table 1. Conclusion Working during the pandemic exposed healthcare professionals from pulmonary institutions not only to the increased work load, but also to many emotional challenges, leading to higher levels of professional burnout and distress, as showed in our study.

      • Will There Be a Permanent Problem with Tuberculosis in Future Due to the Second Category of Patients in Serbia

        ( Miroslav Ilic ),( Ivan Kopitovic ),( Jovan Javorac ),( Darinka Kukavica ),( Nevena Savic ),( Danijela Vukosav ),( Nensi Lalic ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

        Background The second category of tuberculosis (TB) patients present a tremendous problem for each subsequent treatment of tuberculosis and for society. The possibility of the appearance of resistant forms among these patients is more certain nowadays. The aim of this study was to analyze the possible problems that influence the Results of therapy among patients who belong to the second category. Methods This research included a 16-year period (from 2005 to 2020) at the Institute for Pulmonary Diseases of Vojvodina (Serbia). The effects of treatment were evaluated using univariate and multivariate logistic regression analysis. Results There were 223 treated patients in the second category; 17.1% of them were without elementary school education. Almost 50% were unemployed, while every fifth patient was an alcoholic or socially disadvantaged (compared to newly registered p=0.029). In the group of 45-64 years of age, there were 2/3 (149) of patients. Every third patient was treated for TB in youth, while 12% were treated for TB in the previous year. Most patients in this category had previous TB treatment - once (195, 87.4%) or twice (23, 10.3%). Extended regimens were implemented in almost 23% of patients (compared to newly registered p=0.018), while interrupted treatment as an outcome was observed in 21.3% of patients (p=0.008). Independent predictors for belonging to the second category were patients with/without elementary school (RR 1.278; 95% CI (1.108 - 2.573); p=0.032) and patients with alcoholic abuse (RR 2.806; 95% CI (1.683-4.758); p=0.029). Multivariate analysis identified the level of education as an independent predictor for being in the second category. Conclusions Vulnerable populations who were previously treated for TB need continuous monitoring with the aim of preventing resistant forms of the disease.

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