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      • KCI등재

        Study of the preparation and electrochemical performance of porous carbon derived from hypercrosslinked polymers

        Wu Lili,Wang Pitao,Chen Xinguo,Zhang Jianqiang,Luo Heming 한국탄소학회 2022 Carbon Letters Vol.32 No.3

        Hypercrosslinked polymers HCPs have been widely used as precursors to prepare porous carbon materials because of their highly ordered porous structure and large specific surface area. In this paper, we used a solvothermal method to prepare a hypercrosslinked polymer, and the HCPC-700-A was prepared using an activation method with the hypercrosslinked polymer as the precursor. The effects of different carbon–alkali ratios on the microstructure, composition and electrochemical properties of porous carbon HCP were studied. The results show that the surface of porous carbon HCPC-700-A presents a relatively regular geometric shape, and a large number of pore structures are mainly micro- and mesopores. The specific surface area is 2074.53 m2 g−1, and the average pore size is between 1.29 and 1.93 nm. Porous carbon HCPC-700-1:2 has excellent electrochemical performance in 1 M H2SO4, and the specific capacitance is up to 464.4 F g−1 at a current density of 1 A g−1. The specific capacitance decay rate is 29.72% when the current density is increased from 1 A g−1 to 8 A g−1. After 5000 cycles, the capacitance retention rate is 91.16% at a current density of 2 A g−1, showing excellent electrochemical performance, good cycle stability and perfect energy storage performance. This research provides new experimental ideas for HCPs in the electrochemical energy storage field.

      • KCI등재

        Genetic diversity and phylogenetic analysis of porcine reproductive and respiratory syndrome virus in southern China from 2007 to 2014

        Qiwen Wu,Zhili Li,Guanqun Zhang,Jianqiang Niu,Xiduo Zeng,Baoli Sun,Jingyun Ma 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.3

        Porcine reproductive and respiratory syndrome virus (PRRSV) has a high degree of genetic variation. In this study, we characterized the genetic variation and evolutionary relationships among circulating PRRSV strains in southern China. We analyzed 29 NSP2 strains and 150 ORF5 strains from clinical samples collected in southern China during 2007–2014. The alignment results showed that the nucleotide identity similarities of the two genes among these strains were 80.5%–99.7% and 80.9%–100%, respectively. Phylogenetic analysis based on the NSP2 gene showed that highly pathogenic (HP)-PRRSV was still the dominant virus in southern China from 2013 to 2014. Compared with reference strains CH-1a and VR-2332, the field strain 131101-GD-SHC, which shared high homology with JXA1-P170, had a novel 12 amino acid deletion at position 499-510. Phylogenetic analysis based on the ORF5 gene showed that HP-PRRSV, VR2332-like strains, and QYYZ-like strains were simultaneously circulating in southern China from 2007 to 2014, suggesting that, in recent years, the type 2 PRRSV was more diverse in southern China. In conclusion, mutations in the decoy epitope and primary neutralizing epitope could be markers of viral evolution and used to study evolutionary relationships among PRRSV strains in China.

      • KCI등재

        Mesoscopic investigation of frost crystal nucleation on cold surface based on the lattice-Boltzmann method

        Jianying Gong,Jianqiang Hou,Liangwei Yang,Weifeng Wu,Guojun Li,Tieyu Gao 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.4

        A lattice Boltzmann method (LBM) two-dimensional (2D) mesoscopic model is presented for studying the frost crystal nucleation process involved in liquid-solid phase change on a cold surface. In order to make the simulation more realistic, the actual frost crystal nucleus deformation process is considered in this model. The simulation results agree well with our experimental results. Detailed analysis was made on the dynamic behavior of liquid-solid phase change and heat transfer happening in the frost crystal nucleation process. Results are presented for the evolution law of frost crystal nucleus deformation, dynamic solid-liquid phase change process as well as the dynamic distribution of frost nucleus interior temperature during frost crystal nucleation. In addition, the occurrence of frost crystal nucleus deformation is explained by the theory of crystal growth. Finally, where and why the initial position of frost crystal growth happens is also revealed. Furthermore, the reason why the hydrophobic surface can delay the droplet freezing and why the frost growth is faster on the hydrophobic surface after the droplet is frozen is analyzed based on this model.

      • KCI등재

        COORDINATED COLLISION AVOIDANCE FOR CONNECTED VEHICLES USING RELATIVE KINETIC ENERGY DENSITY

        Manjiang Hu,Jian Wu,Hongmao Qin,Yougang Bian,Biao Xu,Qing Xu,Jugang He,Jianqiang Wang 한국자동차공학회 2017 International journal of automotive technology Vol.18 No.5

        Vehicular collision often leads to serious casualties and traffic congestion, and the consequences are worse for multiple-vehicle collision. Many previous works on collision avoidance have only focused on the case for two consecutive vehicles using on-board sensors, which ignored the influence on upstream traffic flow. This paper proposes a novel coordinated collision avoidance (CCA) strategy for connected vehicles, which has potential to avoid collision and smooth the braking behaviors of multiple vehicles, leading to an improvement of traffic smoothness. Specifically, model predictive control (MPC) framework is used to formulate the CCA into an optimization problem, where the objective is to minimize the total relative kinetic energy density (RKED) among connected vehicles. Monte Carlo simulations are used to demonstrate the effectiveness of proposed CCA strategy by comparison with other two strategies. Among all the three control strategies, the RKED based control strategy shows the best performance of collision avoidance, including the best crash prevention rates (99.2 % on dry asphalt road and 90.5 % on wet asphalt road) and the best control of distance headways between vehicles.

      • KCI등재SCOPUSSCIE

        The Role of RUNX1 in NF1-Related Tumors and Blood Disorders

        Na, Youjin,Huang, Gang,Wu, Jianqiang Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.2

        Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder. NF1 patients are predisposed to formation of several type solid tumors as well as to juvenile myelomonocytic leukemia. Loss of NF1 results in dysregulation of MAPK, PI3K and other signaling cascades, to promote cell proliferation and to inhibit cell apoptosis. The RUNX1 gene is associated with stem cell function in many tissues, and plays a key role in the fate of stem cells. Aberrant RUNX1 expression leads to context-dependent tumor development, in which RUNX1 may serve as a tumor suppressor or an oncogene in specific tissue contexts. The co-occurrence of mutation of NF1 and RUNX1 is detected rarely in several cancers and signaling downstream of RAS-MAPK can alter RUNX1 function. Whether aberrant RUNX1 expression contributes to NF1-related tumorigenesis is not fully understood. This review focuses on the role of RUNX1 in NF1-related tumors and blood disorders, and in sporadic cancers.

      • KCI등재

        The intrinsic relationship between color variation and performances of the deteriorated aviation lubrication oil

        Jun Ma,Shaojun Ruan,Jianqiang Hu,Yuanbao Sun,Yiwei Fei,Xufeng Jiang,Shibao Dong,Teng Chen,Nan Wu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.92 No.-

        Dose the blackened lubrication oil needs to be replaced forflying safety? Since there is very limited roomfor inaccurate assessment of oil quality due to strictflying safety standards, much aviation lubrication oilis disposed in advance long before their service life. More important, aircrafts still face the fatalchallenges from unpredictable lubrication oil deterioration. Color change is surely a significant signal to diagnose the quality of lubrication oils. Based on thecolorimeter, the color numbers of the testing lubrication oils are measured in this paper to identify thecolor variation degree of the oxidized lubrication oils. Then the molecular structures of the oxidizedlubrication oils are investigated tofind the intrinsic relationship between the oxidation products andcolor numbers. Based on key performances of the oxidized oil samples, the oil quality is undoubtfullydeteriorated which is coincident with the variation of color number. The color numbers of the usedaviation lubrication oils could provide an alternative way to readily and quickly measure the declinedegree and residual lifetime.

      • KCI등재

        Experimental Investigation on Critical Heat Flux in Bilaterally Heated Annulus with equal heat flux on both sides

        Gui Miao,Guo Junliang,Kong Huanjun,Wu Pan,Shan Jianqiang,Peng Yujiao 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.9

        A phenomenological study on CHF in a bilaterally heated annulus with equal heat flux on both sides was experimentally performed. The working fluid of the present test was R-134a. Variation characteristics of CHF and transition of CHF occurrence location were investigated under different pressure, mass flux and quality conditions. With the increase of critical thermodynamic quality, it was found that CHF first occurred on the outer surface of the annulus, then simultaneously occurred on both sides, and finally occurred on the inner surface at relatively high critical quality. After the CHF location transitioned to the inner rod, the sharp fall of CHF in the limiting critical quality region was observed. The critical quality corresponding to the CHF location transition decreased with the increase of mass flux and pressure. Besides, CHF in tube, internally heated, externally heated and bilaterally heated annuli were compared under the same hydraulic diameter conditions. The present study is conducive to improving the understanding of complicated CHF mechanism in bilaterally heated annulus, enriching the experimental database, and providing evidence for developing accurate CHF mechanism model for annuli.

      • KCI등재SCOPUSSCIE

        The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

        Yokota, Asumi,Huo, Li,Lan, Fengli,Wu, Jianqiang,Huang, Gang Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.2

        RUNX1 plays an important role in the regulation of normal hematopoiesis. RUNX1 mutations are frequently found and have been intensively studied in hematological malignancies. Germline mutations in RUNX1 cause familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML). Somatic mutations of RUNX1 are observed in various types of hematological malignancies, such as AML, acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS), myeloproliferative neoplasm (MPN), chronic myelomonocytic leukemia (CMML), and congenital bone marrow failure (CBMF). Here, we systematically review the clinical and molecular characteristics of RUNX1 mutations, the mechanisms of pathogenesis caused by RUNX1 mutations, and potential therapeutic strategies to target RUNX1-mutated cases of hematological malignancies.

      • KCI등재

        Molecular characterization and phylogenetic analysis of pseudorabies virus variants isolated from Guangdong province of southern China during 2013–2014

        Jindai Fan,Xiduo Zeng,Guanqun Zhang,Qiwen Wu,Jianqiang Niu,Baoli Sun,Qingmei Xie,Jingyun Ma 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.3

        Outbreaks of pseudorabies (PR) have occurred in southern China since late 2011, resulting in significant economic impacts on the swine industry. To identify the cause of PR outbreaks, especially among vaccinated pigs, 11 pseudorabies virus (PRV) field strains were isolated from Guangdong province during 2013–2014. Their major viral genes (gE, TK, gI, PK, gD, 11K, and 28K) were analyzed in this study. Insertions or deletions were observed in gD, gE, gI and PK genes compared with other PRV isolates from all over the world. Furthermore, sequence alignment showed that insertions in gD and gE were unique molecular characteristics of the new prevalent PRV strains in China. Phylogenetic analysis showed that our isolates were clustered in an independent branch together with other strains isolated from China in recent years, and that they showed a closer genetic relationship with earlier isolates from Asia. Our results suggest that these isolates are novel PRV variants with unique molecular signatures.

      • KCI등재

        Clinical Comparison of Proximal Gastrectomy With Double-Tract Reconstruction Versus Total Gastrectomy With Roux-en-Y Anastomosis for Siewert Type II/III Adenocarcinoma of the Esophagogastric Junction

        Ma Xiaoming,Zhao Mingzuo,Wang Jian,Pan Haixing,Wu Jianqiang,Xing Chungen 대한위암학회 2022 Journal of gastric cancer Vol.22 No.3

        Purpose The incidence of adenocarcinoma of the esophagogastric junction (AEG) has increased in recent years, and the optimal surgical strategy for AEG remains highly controversial. We aimed to evaluate the safety and efficacy of proximal gastrectomy with double-tract reconstruction (PG-DT) for the treatment of patients with AEG. Materials and Methods We retrospectively analyzed patients with Siewert type II/III AEG between January 2013 and July 2018. Clinicopathological characteristics, survival, surgical outcomes, quality of life (QOL), and nutritional status were compared between the PG-DT and total gastrectomy with Roux-en-Y anastomosis (TG-RY) groups. Results After propensity score matching, 33 patients in each group were analyzed. There were no statistical differences between the 2 groups in terms of disease-free survival and overall survival. The surgical option was not an independent prognostic factor based on the multivariate analysis. In addition, no differences were found in terms of surgical complications. There were no significant differences in QOL assessed by the Visick grade, Gastrointestinal Symptom Rating Scale, or endoscopic findings. Furthermore, the long-term nutritional advantage of the PG-DT group was significantly greater than that of the TG-RY group. Conclusions PG-DT is a safe and effective procedure for patients with local Siewert type II/III AEG, regardless of the TNM stage. Purpose The incidence of adenocarcinoma of the esophagogastric junction (AEG) has increased in recent years, and the optimal surgical strategy for AEG remains highly controversial. We aimed to evaluate the safety and efficacy of proximal gastrectomy with double-tract reconstruction (PG-DT) for the treatment of patients with AEG. Materials and Methods We retrospectively analyzed patients with Siewert type II/III AEG between January 2013 and July 2018. Clinicopathological characteristics, survival, surgical outcomes, quality of life (QOL), and nutritional status were compared between the PG-DT and total gastrectomy with Roux-en-Y anastomosis (TG-RY) groups. Results After propensity score matching, 33 patients in each group were analyzed. There were no statistical differences between the 2 groups in terms of disease-free survival and overall survival. The surgical option was not an independent prognostic factor based on the multivariate analysis. In addition, no differences were found in terms of surgical complications. There were no significant differences in QOL assessed by the Visick grade, Gastrointestinal Symptom Rating Scale, or endoscopic findings. Furthermore, the long-term nutritional advantage of the PG-DT group was significantly greater than that of the TG-RY group. Conclusions PG-DT is a safe and effective procedure for patients with local Siewert type II/III AEG, regardless of the TNM stage.

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